PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis
出版年份 2018 全文链接
标题
PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 8, Pages 2317
出版商
MDPI AG
发表日期
2018-08-07
DOI
10.3390/ijms19082317
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Mitochondrial quality control in AMD: does mitophagy play a pivotal role?
- (2018) Juha M. T. Hyttinen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Distinct CD40L receptors mediate inflammasome activation and secretion of IL-1β and MCP-1 in cultured human retinal pigment epithelial cells
- (2018) Zong-Mei Bian et al. EXPERIMENTAL EYE RESEARCH
- Pgc-1αrepression and high-fat diet induce age-related macular degeneration-like phenotypes in mice
- (2018) Meng Zhang et al. Disease Models & Mechanisms
- Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration
- (2018) Cassandra Kosmidou et al. Scientific Reports
- Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?
- (2017) Janusz Blasiak et al. Oxidative Medicine and Cellular Longevity
- Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage
- (2017) Sonali Nashine et al. Cell Death & Disease
- Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration
- (2017) Deborah A. Ferrington et al. Redox Biology
- Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
- (2017) Viktor I. Korolchuk et al. EBioMedicine
- Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration
- (2016) Kai Kaarniranta et al. CELL BIOLOGY AND TOXICOLOGY
- Inflammation and its role in age-related macular degeneration
- (2016) Anu Kauppinen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Morphological and Functional Characteristic of Senescent Cancer Cells
- (2016) Ewa Sikora et al. CURRENT DRUG TARGETS
- Induction of oxidative and nitrosative stresses in human retinal pigment epithelial cells by all-trans-retinal
- (2016) Xue Zhu et al. EXPERIMENTAL CELL RESEARCH
- Increased retinal mtDNA damage in the CFH variant associated with age-related macular degeneration
- (2016) Deborah A. Ferrington et al. EXPERIMENTAL EYE RESEARCH
- Repressed SIRT1/PGC-1α pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration
- (2016) Nady Golestaneh et al. Journal of Translational Medicine
- Regulation of Mitochondrial Biogenesis and Its Intersection with Inflammatory Responses
- (2015) Anne D. Cherry et al. ANTIOXIDANTS & REDOX SIGNALING
- The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo
- (2015) Petra Sabine Eisele et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PINK1/Parkin-mediated mitophagy in mammalian cells
- (2015) Akinori Eiyama et al. CURRENT OPINION IN CELL BIOLOGY
- Promoter-specific regulation ofPPARGC1Agene expression in human skeletal muscle
- (2015) Daniil V Popov et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
- (2015) Murilo F. Roggia et al. PLoS One
- PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases
- (2015) Shiqin Xiong et al. Cell Reports
- Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
- (2014) Sayak K Mitter et al. Autophagy
- Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling
- (2014) Mallika Valapala et al. Autophagy
- Guidelines for the management of neovascular age-related macular degeneration by the European Society of Retina Specialists (EURETINA)
- (2014) Ursula Schmidt-Erfurth et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis
- (2014) Osamu Sawada et al. EXPERIMENTAL EYE RESEARCH
- Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue
- (2014) JIAN-ZHENG ZHANG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart
- (2014) Thomas K. Sin et al. JOURNAL OF PHYSIOLOGY-LONDON
- Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
- (2014) C. Franceschi et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Involvement of Endoplasmic Reticulum Stress in All-Trans-Retinal-Induced Retinal Pigment Epithelium Degeneration
- (2014) Jie Li et al. TOXICOLOGICAL SCIENCES
- Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Is a Central Negative Regulator of Vascular Senescence
- (2013) Shiqin Xiong et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration
- (2013) Kai Kaarniranta et al. Autophagy
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- A Role for Peroxisome Proliferator-Activated Receptor γ Coactivator-1 in the Control of Mitochondrial Dynamics During Postnatal Cardiac Growth
- (2013) Ola J. Martin et al. CIRCULATION RESEARCH
- The role of SIRT1 in ocular aging
- (2013) Tatsuya Mimura et al. EXPERIMENTAL EYE RESEARCH
- Peroxisome Proliferator-activated Receptor γ Co-activator 1-α as a Critical Co-activator of the Murine Hepatic Oxidative Stress Response and Mitochondrial Biogenesis inStaphylococcus aureusSepsis
- (2013) Anne D. Cherry et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA Sequence Variants in PPARGC1A, a Gene Encoding a Coactivator of the ω-3 LCPUFA Sensing PPAR-RXR Transcription Complex, Are Associated with NV AMD and AMD-Associated Loci in Genes of Complement and VEGF Signaling Pathways
- (2013) John Paul SanGiovanni et al. PLoS One
- PGC-1α Regulates Normal and Pathological Angiogenesis in the Retina
- (2012) Magali Saint-Geniez et al. AMERICAN JOURNAL OF PATHOLOGY
- Intense Physiological Light Upregulates Vascular Endothelial Growth Factor and Enhances Choroidal Neovascularization via Peroxisome Proliferator-Activated Receptor γ Coactivator-1α in Mice
- (2012) Takashi Ueta et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Mitochondrial Dysfunction in Retinal Diseases
- (2012) Megha Barot et al. CURRENT EYE RESEARCH
- Genetic Variability in DNA Repair Proteins in Age-Related Macular Degeneration
- (2012) Janusz Blasiak et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- RPE cell senescence: A key contributor to age-related macular degeneration
- (2012) Michael R. Kozlowski MEDICAL HYPOTHESES
- Angiotensin II Requires Zinc and Downregulation of the Zinc Transporters ZnT3 and ZnT10 to Induce Senescence of Vascular Smooth Muscle Cells
- (2012) Nikolay Patrushev et al. PLoS One
- PGC-1α Determines Light Damage Susceptibility of the Murine Retina
- (2012) Anna Egger et al. PLoS One
- Peroxisomal Localization and Circadian Regulation of Ubiquitin-Specific Protease 2
- (2012) Matthew M. Molusky et al. PLoS One
- Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis
- (2011) Pablo J Fernandez-Marcos et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
- (2011) Joo-Ho Shin et al. CELL
- Enhanced retinal pigment epithelium regeneration after injury in MRL/MpJ mice
- (2011) Huiming Xia et al. EXPERIMENTAL EYE RESEARCH
- Uncoupling proteins and the control of mitochondrial reactive oxygen species production
- (2011) Ryan J. Mailloux et al. FREE RADICAL BIOLOGY AND MEDICINE
- PGC-1α, a Key Modulator of p53, Promotes Cell Survival upon Metabolic Stress
- (2011) Nirmalya Sen et al. MOLECULAR CELL
- Telomere dysfunction induces metabolic and mitochondrial compromise
- (2011) Ergün Sahin et al. NATURE
- The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
- (2011) Maria M. Mihaylova et al. NATURE CELL BIOLOGY
- PGC-1α at the intersection of bioenergetics regulation and neuron function: From Huntington's disease to Parkinson's disease and beyond
- (2011) Taiji Tsunemi et al. PROGRESS IN NEUROBIOLOGY
- The bisretinoids of retinal pigment epithelium
- (2011) Janet R. Sparrow et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Impact of cellular senescence signature on ageing research
- (2010) Ewa Sikora et al. AGEING RESEARCH REVIEWS
- Mitochondrial ROS Generation and Its Regulation: Mechanisms Involved in H2O2 Signaling
- (2010) Michel Rigoulet et al. ANTIOXIDANTS & REDOX SIGNALING
- DNA damage and repair in age-related macular degeneration
- (2010) Janusz Blasiak Frontiers in Bioscience-Landmark
- Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells
- (2010) Lu Zhu et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia
- (2009) Weiping Qin et al. ARCHIVES OF NEUROLOGY
- Identification and characterization of an alternative promoter of the human PGC-1α gene
- (2009) Toyo Yoshioka et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications
- (2009) Jin-Qiang Chen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging
- (2009) Dao-Fu Dai et al. CIRCULATION
- PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
- (2009) Carles Cantó et al. CURRENT OPINION IN LIPIDOLOGY
- PGC-1α/β induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders
- (2009) Sarika Srivastava et al. HUMAN MOLECULAR GENETICS
- Alternative mRNA Splicing Produces a Novel Biologically Active Short Isoform of PGC-1α
- (2009) Yubin Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice
- (2009) Akiko Maeda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Isoform-Specific Increases in Murine Skeletal Muscle Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α (PGC-1α) mRNA in Response to β2-Adrenergic Receptor Activation and Exercise
- (2008) Shinji Miura et al. ENDOCRINOLOGY
- SCFCdc4 acts antagonistically to the PGC-1 transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis
- (2008) B. L. Olson et al. GENES & DEVELOPMENT
- A PGC-1α-O-GlcNAc Transferase Complex Regulates FoxO Transcription Factor Activity in Response to Glucose
- (2008) Michael P. Housley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PGC-1-related Coactivator Complexes with HCF-1 and NRF-2β in Mediating NRF-2(GABP)-dependent Respiratory Gene Expression
- (2008) Kristel Vercauteren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cellular senescence and organismal aging
- (2008) Jessie C. Jeyapalan et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Sirt1 protects against high-fat diet-induced metabolic damage
- (2008) P. T. Pfluger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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