Involvement of Endoplasmic Reticulum Stress in All-Trans-Retinal-Induced Retinal Pigment Epithelium Degeneration

All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis

(2014) Osamu Sawada et al.   EXPERIMENTAL EYE RESEARCH

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mild Endoplasmic Reticulum Stress Promotes Retinal Neovascularization via Induction of BiP/GRP78

(2013) Shinsuke Nakamura et al.   PLoS One

Asiatic acid protects primary neurons against C2-ceramide-induced apoptosis

(2012) Xiangnan Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction

(2012) Guorui Dou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reduction of All-trans-retinal in Vertebrate Rod Photoreceptors Requires the Combined Action of RDH8 and RDH12

(2012) Chunhe Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

All-TransRetinal Mediates Light-Induced Oxidation in Single Living Rod Photoreceptors†

(2012) Kosuke Masutomi et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

The endoplasmic reticulum is a target organelle for trivalent dimethylarsinic acid (DMAIII)-induced cytotoxicity

(2012) Hua Naranmandura et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondria Are the Main Target Organelle for Trivalent Monomethylarsonous Acid (MMAIII)-Induced Cytotoxicity

(2011) Hua Naranmandura et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mechanism of All-trans-retinal Toxicity with Implications for Stargardt Disease and Age-related Macular Degeneration

(2011) Yu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma

(2011) Gulab S. Zode et al.   JOURNAL OF CLINICAL INVESTIGATION

Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound  -phenylethyl isothiocyanate

(2010) Y. Hu et al.   BLOOD

Retinol dehydrogenases (RDHs) in the visual cycle

(2010) Ryan O. Parker et al.   EXPERIMENTAL EYE RESEARCH

ATF4 and the integrated stress response are induced by ethanol and cytochrome P450 2E1 in human hepatocytes

(2010) Laurent Magne et al.   JOURNAL OF HEPATOLOGY

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis

(2010) Samar H. Ibrahim et al.   JOURNAL OF HEPATOLOGY

Activation transcription factor-4 and the acute vascular response to injury

(2010) Kristine P. Malabanan et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Lead Induces the Expression of Endoplasmic Reticulum Chaperones GRP78 and GRP94 in Vascular Endothelial Cells via the JNK-AP-1 Pathway

(2010) Yasuhiro Shinkai et al.   TOXICOLOGICAL SCIENCES

The role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration

(2009) Robert S. Molday et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

ROS-driven Akt dephosphorylation at Ser-473 is involved in 4-HPR-mediated apoptosis in NB4 cells

(2009) Ji Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice

(2009) Akiko Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipid meets all-trans-retinal: the making of RPE bisretinoids

(2009) Janet R. Sparrow et al.   JOURNAL OF LIPID RESEARCH

Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells

(2008) Shikun He et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance

(2008) Akiko Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Ero1 and redox homeostasis in the endoplasmic reticulum

(2007) Carolyn S. Sevier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH