Pgc-1αrepression and high-fat diet induce age-related macular degeneration-like phenotypes in mice

Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

(2017) Nady Golestaneh et al.   Cell Death & Disease

Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage

(2017) Sonali Nashine et al.   Cell Death & Disease

Functional Deficits Precede Structural Lesions in Mice With High-Fat Diet–Induced Diabetic Retinopathy

(2016) Rithwick Rajagopal et al.   DIABETES

An easy, rapid method to isolate RPE cell protein from the mouse eye

(2016) Hong Wei et al.   EXPERIMENTAL EYE RESEARCH

High-resolution contrast-enhanced optical coherence tomography in mice retinae

(2016) Debasish Sen et al.   JOURNAL OF BIOMEDICAL OPTICS

Repressed SIRT1/PGC-1α pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration

(2016) Nady Golestaneh et al.   Journal of Translational Medicine

Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: A novel culture model for dry AMD

(2016) David M. Rabin et al.   Aging-US

Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscle

(2015) Anna Vainshtein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Investigating Mitochondria as a Target for Treating Age-Related Macular Degeneration

(2015) M. R. Terluk et al.   JOURNAL OF NEUROSCIENCE

Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy

(2015) S. Scott Whitmore et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD

(2014) Sayak K Mitter et al.   Autophagy

Choriocapillaris breakdown precedes retinal degeneration in age-related macular degeneration

(2014) Antje Biesemeier et al.   NEUROBIOLOGY OF AGING

DNA Sequence Variants in PPARGC1A, a Gene Encoding a Coactivator of the ω-3 LCPUFA Sensing PPAR-RXR Transcription Complex, Are Associated with NV AMD and AMD-Associated Loci in Genes of Complement and VEGF Signaling Pathways

(2013) John Paul SanGiovanni et al.   PLoS One

PGC-1α Regulates Normal and Pathological Angiogenesis in the Retina

(2012) Magali Saint-Geniez et al.   AMERICAN JOURNAL OF PATHOLOGY

Novel method for the rapid isolation of RPE cells specifically for RNA extraction and analysis

(2012) Cynthia Xin-Zhao Wang et al.   EXPERIMENTAL EYE RESEARCH

Animal models of age related macular degeneration

(2012) Mark E. Pennesi et al.   MOLECULAR ASPECTS OF MEDICINE

Understanding age-related macular degeneration (AMD): Relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex

(2012) Imran Bhutto et al.   MOLECULAR ASPECTS OF MEDICINE

PGC-1α Determines Light Damage Susceptibility of the Murine Retina

(2012) Anna Egger et al.   PLoS One

Impact of PGC-1α on the topology and rate of superoxide production by the mitochondrial electron transport chain

(2011) Shane Austin et al.   FREE RADICAL BIOLOGY AND MEDICINE

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

Genome-wide Coactivation Analysis of PGC-1α Identifies BAF60a as a Regulator of Hepatic Lipid Metabolism

(2008) Siming Li et al.   Cell Metabolism