Non-Synonymous Single Nucleotide Polymorphisms in the P2X Receptor Genes: Association with Diseases, Impact on Receptor Functions and Potential Use as Diagnosis Biomarkers
出版年份 2014 全文链接
标题
Non-Synonymous Single Nucleotide Polymorphisms in the P2X Receptor Genes: Association with Diseases, Impact on Receptor Functions and Potential Use as Diagnosis Biomarkers
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 15, Issue 8, Pages 13344-13371
出版商
MDPI AG
发表日期
2014-07-30
DOI
10.3390/ijms150813344
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Gain and Loss of Function of P2X7 Receptors: Mechanisms, Pharmacology and Relevance to Diabetic Neuropathic Pain
- (2014) Daniel Ursu et al. Molecular Pain
- Lack of Association of P2RX7 Gene rs2230912 Polymorphism with Mood Disorders: A Meta-Analysis
- (2014) Wen-Ping Feng et al. PLoS One
- Inherent Dynamics of Head Domain Correlates with ATP-Recognition of P2X4 Receptors: Insights Gained from Molecular Simulations
- (2014) Li-Dong Huang et al. PLoS One
- Variations in inflammation-related genes may be associated with childhood febrile seizure susceptibility
- (2014) Hedley C.A. Emsley et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- P2X7 Gene Polymorphisms and Risk Assessment for Pulmonary Tuberculosis in Asian Indians
- (2013) Venkatasubramanian Sambasivan et al. DISEASE MARKERS
- A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age-related macular degeneration
- (2013) Ben J. Gu et al. FASEB JOURNAL
- A novel P2RX2 mutation in an Italian family affected by autosomal dominant nonsyndromic hearing loss
- (2013) Flavio Faletra et al. GENE
- Mutation of the ATP-gated P2X2 receptor leads to progressive hearing loss and increased susceptibility to noise
- (2013) D. Yan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATP-gated ion channels mediate adaptation to elevated sound levels
- (2013) G. D. Housley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insights into the Molecular Mechanisms Underlying Mammalian P2X7 Receptor Functions and Contributions in Diseases, Revealed by Structural Modeling and Single Nucleotide Polymorphisms
- (2013) Lin-Hua Jiang et al. Frontiers in Pharmacology
- ATP activates P2X receptors to mediate gap junctional coupling in the cochlea
- (2012) Yan Zhu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The P2X7 loss-of-function Glu496Ala polymorphism affects ex vivo cytokine release and protects against the cytotoxic effects of high ATP-levels
- (2012) Anke Wesselius et al. BMC IMMUNOLOGY
- The His155Tyr (489C>T) single nucleotide polymorphism of P2RX7 gene confers an enhanced function of P2X7 receptor in immune cells from patients with rheumatoid arthritis
- (2012) Liliana Portales-Cervantes et al. CELLULAR IMMUNOLOGY
- Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures
- (2012) Niklas R Jørgensen et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women
- (2012) Alison Gartland et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Molecular mechanism of ATP binding and ion channel activation in P2X receptors
- (2012) Motoyuki Hattori et al. NATURE
- Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity
- (2012) Robert E Sorge et al. NATURE MEDICINE
- Neuromodulation by Extracellular ATP and P2X Receptors in the CNS
- (2012) Baljit S. Khakh et al. NEURON
- Functional polymorphisms in the P2X7 receptor gene are associated with osteoporosis
- (2012) L. B. Husted et al. OSTEOPOROSIS INTERNATIONAL
- Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients
- (2012) A. Wesselius et al. OSTEOPOROSIS INTERNATIONAL
- A Common Missense Variant in the ATP Receptor P2X7 Is Associated with Reduced Risk of Cardiovascular Events
- (2012) Olof Gidlöf et al. PLoS One
- Moving through the gate in ATP-activated P2X receptors
- (2012) Ruotian Jiang et al. TRENDS IN BIOCHEMICAL SCIENCES
- Pharmacological properties of the rhesus macaque monkey P2X7 receptor
- (2011) Helen J Bradley et al. BRITISH JOURNAL OF PHARMACOLOGY
- Gain-of-function of P2X7 receptor gene variants in multiple sclerosis
- (2011) Olatz Oyanguren-Desez et al. CELL CALCIUM
- P2RX7 genotype association in severe sepsis identified by a novel Multi-Individual Array for rapid screening and replication of risk SNPs
- (2011) J. Geistlinger et al. CLINICA CHIMICA ACTA
- A Loss-of-Function Polymorphism in the Human P2X4 Receptor Is Associated With Increased Pulse Pressure
- (2011) Leanne Stokes et al. HYPERTENSION
- P2X7 receptor gene polymorphism analysis in rheumatoid arthritis
- (2011) A. Al-Shukaili et al. International Journal of Immunogenetics
- Residues 155 and 348 Contribute to the Determination of P2X7Receptor Function via Distinct Mechanisms Revealed by Single-nucleotide Polymorphisms
- (2011) Helen J. Bradley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Visualization of flow-induced ATP release and triggering of Ca2+ waves at caveolae in vascular endothelial cells
- (2011) K. Yamamoto et al. JOURNAL OF CELL SCIENCE
- P2X7 Is a Scavenger Receptor for Apoptotic Cells in the Absence of Its Ligand, Extracellular ATP
- (2011) B. J. Gu et al. JOURNAL OF IMMUNOLOGY
- Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
- (2011) NATURE GENETICS
- Structural interpretation of P2X receptor mutagenesis studies on drug action
- (2010) Richard J Evans BRITISH JOURNAL OF PHARMACOLOGY
- Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion
- (2010) Leanne Stokes et al. FASEB JOURNAL
- Evidence for associations between the purinergic receptor P2X7 (P2RX7) and toxoplasmosis
- (2010) S E Jamieson et al. GENES AND IMMUNITY
- The diagnosis of osteoporosis
- (2010) John A. Kanis et al. JOURNAL OF BONE AND MINERAL RESEARCH
- P2X7 Receptor-Mediated Killing of an Intracellular Parasite, Toxoplasma gondii, by Human and Murine Macrophages
- (2010) M. P. Lees et al. JOURNAL OF IMMUNOLOGY
- Why prevent, diagnose and treat congenital toxoplasmosis?
- (2010) Rima McLeod et al. MEMORIAS DO INSTITUTO OSWALDO CRUZ
- ATP-mediated potassium recycling in the cochlear supporting cells
- (2010) Yan Zhu et al. Purinergic Signalling
- New structure enlivens interest in P2X receptors
- (2010) Liam E. Browne et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- P2RX7: A bipolar and unipolar disorder candidate susceptibility gene?
- (2009) Elaine K. Green et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Variation inP2RX7candidate gene (rs2230912) is not associated with bipolar I disorder and unipolar major depression in four European samples
- (2009) Maria Grigoroiu-Serbanescu et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Genetics of age-related macular degeneration
- (2009) Andrew YC Ting et al. CURRENT OPINION IN OPHTHALMOLOGY
- Polar Residues in the Second Transmembrane Domain of the Rat P2X2 Receptor That Affect Spontaneous Gating, Unitary Conductance, and Rectification
- (2009) L. Cao et al. JOURNAL OF NEUROSCIENCE
- The P2X7 Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore
- (2009) M. Monif et al. JOURNAL OF NEUROSCIENCE
- Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions
- (2009) Sébastien Roger et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Crystal structure of the ATP-gated P2X4 ion channel in the closed state
- (2009) Toshimitsu Kawate et al. NATURE
- Association between depression and the Gln460Arg polymorphism of P2RX7 Gene: A dimensional approach
- (2008) Krisztina Hejjas et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Signaling at Purinergic P2X Receptors
- (2008) Annmarie Surprenant et al. Annual Review of Physiology
- P2X7 receptor as sensitive flow sensor for ERK activation in osteoblasts
- (2008) Hisashi Okumura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibition of P2X7 receptors by divalent cations: old action and new insight
- (2008) Lin-Hua Jiang EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- Lack of association between polymorphisms in the P2X7gene and tuberculosis in a Chinese Han population
- (2008) Jing Xiao et al. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
- P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis
- (2008) Nattapon Panupinthu et al. JOURNAL OF CELL BIOLOGY
- Opposite Effects of Zinc on Human and Rat P2X2 Receptors
- (2008) R. K. Tittle et al. JOURNAL OF NEUROSCIENCE
- Case–control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders
- (2008) A McQuillin et al. MOLECULAR PSYCHIATRY
- Whole-genome association study of bipolar disorder
- (2008) P Sklar et al. MOLECULAR PSYCHIATRY
- Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
- (2008) Manuel A R Ferreira et al. NATURE GENETICS
- ATP activates P2x receptors and requires extracellular Ca++ participation to modify outer hair cell nonlinear capacitance
- (2008) Ning Yu et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Activation of P2X7 receptors in glial satellite cells reduces pain through downregulation of P2X3 receptors in nociceptive neurons
- (2008) Y. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- P2X7gene polymorphisms do not appear to be a susceptibility gene locus in sporadic cases of systemic lupus erythematosus
- (2008) S. L. Forchap et al. TISSUE ANTIGENS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More