C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment

The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation

(2013) Markus Bosmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2

(2013) Daniel E Croker et al.   IMMUNOLOGY AND CELL BIOLOGY

Inflammatory Responses Induced by Lipopolysaccharide Are Amplified in Primary Human Monocytes but Suppressed in Macrophages by Complement Protein C5a

(2013) V. Seow et al.   JOURNAL OF IMMUNOLOGY

Disruption of the Complement Anaphylatoxin Receptor C5L2 Exacerbates Inflammation in Allergic Contact Dermatitis

(2013) R. Wang et al.   JOURNAL OF IMMUNOLOGY

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway

(2012) Qi Cao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

C5L2 and C5aR interaction in adipocytes and macrophages: Insights into adipoimmunology

(2012) Pegah Poursharifi et al.   CELLULAR SIGNALLING

C5L2: a controversial receptor of complement anaphylatoxin, C5a

(2012) Rui Li et al.   FASEB JOURNAL

C5a Receptor-Dependent Cell Activation by Physiological Concentrations of Desarginated C5a: Insights from a Novel Label-Free Cellular Assay

(2012) E. S. Reis et al.   JOURNAL OF IMMUNOLOGY

G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand?

(2011) Henry F Vischer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Beta-arrestin 2 negatively regulates sepsis-induced inflammation

(2010) Hongkuan Fan et al.   IMMUNOLOGY

The C5a Receptor (C5aR) C5L2 Is a Modulator of C5aR-mediated Signal Transduction

(2010) Claire E. Bamberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

(2010) Laura Albizu et al.   Nature Chemical Biology

C3a and C5a Are Chemotactic Factors for Human Mesenchymal Stem Cells, Which Cause Prolonged ERK1/2 Phosphorylation

(2009) I. U. Schraufstatter et al.   JOURNAL OF IMMUNOLOGY

The human complement fragment receptor, C5L2, is a recycling decoy receptor

(2008) Anne-Marie Scola et al.   MOLECULAR IMMUNOLOGY

Functional roles for C5a receptors in sepsis

(2008) Daniel Rittirsch et al.   NATURE MEDICINE