C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2

The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation

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C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling

(2012) Junxian Lim et al.   FASEB JOURNAL

C5L2 receptor disruption enhances the development of diet-induced insulin resistance in mice

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C5a Receptor-Dependent Cell Activation by Physiological Concentrations of Desarginated C5a: Insights from a Novel Label-Free Cellular Assay

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Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

New insights for C5a and C5a receptors in sepsis

(2012) Chunguang Yan et al.   Frontiers in Immunology

G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand?

(2011) Henry F Vischer et al.   BRITISH JOURNAL OF PHARMACOLOGY

The C5a Receptor (C5aR) C5L2 Is a Modulator of C5aR-mediated Signal Transduction

(2010) Claire E. Bamberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Critical Role for C5L2 in the Pathogenesis of Experimental Allergic Asthma

(2010) X. Zhang et al.   JOURNAL OF IMMUNOLOGY

Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

(2010) Laura Albizu et al.   Nature Chemical Biology

Building a new conceptual framework for receptor heteromers

(2009) Sergi Ferré et al.   Nature Chemical Biology

Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2

(2008) Hyun Lee et al.   IMMUNOLOGY AND CELL BIOLOGY

The human complement fragment receptor, C5L2, is a recycling decoy receptor

(2008) Anne-Marie Scola et al.   MOLECULAR IMMUNOLOGY

Functional roles for C5a receptors in sepsis

(2008) Daniel Rittirsch et al.   NATURE MEDICINE

Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors

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