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Gloria Bartolo
United States
Keck Graduate Institute
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Obesity stigmatisation from obesity researchers
Extremely upsetting to hear. Hope obesity researchers are more aware and cautious of their bias.
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Obesity: ERAD linked to obesity
Amazing find for age-associated obesity.
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Obesity Policy Spotlight: Childhood Obesity
How do childhood obesity rates vary across different socioeconomic regions?
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Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents
It would be amazing to see the efficacy of these drugs in vivo
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In vitro activity of nitroxoline against clinical isolates of Candida species
This drug can inhibit angiogenesis, gram-negative, gram-positive, biofilms, AND candida species?? What else can it do?!
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Cathepsin B inhibitors: Further exploration of the nitroxoline core
Amazing work was done on studying the analogs of nitroxoline.
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Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria
Wow, amazing finding! Especially if further demonstrated in clinical development.
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Nitroxoline induces apoptosis and slows glioma growth in vivo
Is nitroxoline given via injections normally, or only approved for oral use in humans?
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Susceptibility of carbapenemase-producing Enterobacterales (CPE) to nitroxoline
Have preclinical trials started for this drug?
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Nitroxoline: repurposing its antimicrobial to antitumor application
Are there any specific cancers where nitroxoline is more effective against? Also, has nitroxoline ever reached clinical trials yet?
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Gas gangrene-associated gliding motility is regulated by the Clostridium perfringens CpAL/VirSR system
Such an amazing link found between gliding, virulence and theCpAL regulatory network. Fascinating!
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The EngCP endo α-N-acetylgalactosaminidase is a virulence factor involved in Clostridium perfringens gas gangrene infections
In mutant bacterial strains of the EngCP endoα-N-acetylgalactosaminidase, is their virulence attenuated as seen here?
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Inflammasome Activation Induced by Perfringolysin O of Clostridium perfringens and Its Involvement in the Progression of Gas Gangrene
Are all toxins produced by C. perfringens pore-forming?
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Combined therapy with gas gangrene antitoxin and recombinant human soluble thrombomodulin for Clostridium perfringens sepsis in a rat model
How often is the antitoxin given as a treatment for gas gamgrene?
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A Recombinant Probiotic, Lactobacillus casei, Expressing the Clostridium perfringens α-toxoid, as an Orally Vaccine Candidate Against Gas Gangrene and Necrotic Enteritis
Are any GELV vaccines currently approved globally?
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