An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest

Hemostatic Effects of a Novel Estradiol-Based Oral Contraceptive

(2013) Christine Klipping et al.   Drugs in research & development

Effective treatment of heavy and/or prolonged menstrual bleeding without organic cause: pooled analysis of two multinational, randomised, double-blind, placebo-controlled trials of oestradiol valerate and dienogest

(2012) Ian S. Fraser et al.   EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE

Metabolic and Haemostatic Effects of Estradiol Valerate/Dienogest, a Novel Oral Contraceptive

(2011) Wolfgang Junge et al.   CLINICAL DRUG INVESTIGATION

Inhibition of ovulation by NOMAC/E2, a novel monophasic oral contraceptive combining nomegestrol acetate and 17β-oestradiol: A double-blind, randomised, dose-finding pilot study

(2011) Nathalie Chabbert-Buffet et al.   EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE

Comparison of a 24-day and a 21-day pill regimen for the novel combined oral contraceptive, nomegestrol acetate and 17 -estradiol (NOMAC/E2): a double-blind, randomized study

(2011) S. Christin-Maitre et al.   HUMAN REPRODUCTION

Haemostatic effects of a new combined oral contraceptive, nomegestrol acetate/17β-estradiol, compared with those of levonorgestrel/ethinyl estradiol

(2011) Martine Alhenc-Gelas et al.   THROMBOSIS AND HAEMOSTASIS

Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol on ovarian function in comparison to a monophasic combined oral contraceptive containing drospirenone and ethinylestradiol

(2010) Ingrid J. M. Duijkers et al.   EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE

Bleeding pattern and cycle control with an estradiol-based oral contraceptive: a seven-cycle, randomized comparative trial of estradiol valerate/dienogest and ethinyl estradiol/levonorgestrel

(2009) Hans-Joachim Ahrendt et al.   CONTRACEPTION

Pharmacokinetics of an oral contraceptive containing oestradiol valerate and dienogest

(2009) Susan Zeun et al.   EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE

Efficacy and safety of a novel oral contraceptive based on oestradiol (oestradiol valerate/dienogest): A Phase III trial

(2009) Santiago Palacios et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Ovulation inhibition with four variations of a four-phasic estradiol valerate/dienogest combined oral contraceptive: results of two prospective, randomized, open-label studies

(2008) Jan Endrikat et al.   CONTRACEPTION

Suppression of ovarian activity with a drospirenone-containing oral contraceptive in a 24/4 regimen

(2008) Christine Klipping et al.   CONTRACEPTION

Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile

(2007) Shinichi Sasagawa et al.   STEROIDS