PI3K-Akt-mTOR and MAPK signaling pathways in polycystic ovarian syndrome, uterine leiomyomas and endometriosis: an update

Estrogen Receptor-αgene (T/C) Pvu II Polymorphism in Endometriosis and Uterine Fibroids

(2013) Sujatha Govindan et al.   DISEASE MARKERS

Reactive Oxygen Species Controls Endometriosis Progression

(2009) Charlotte Ngô et al.   AMERICAN JOURNAL OF PATHOLOGY

Reactive Oxygen Species Mediate Mitogenic Growth Factor Signaling Pathways in Human Leiomyoma Smooth Muscle Cells1

(2009) Fernando S. Mesquita et al.   BIOLOGY OF REPRODUCTION

Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway

(2009) J. S. Crabtree et al.   CANCER RESEARCH

Human Uterine Smooth Muscle and Leiomyoma Cells Differ in Their Rapid 17β-Estradiol Signaling: Implications for Proliferation

(2009) Erica N. Nierth-Simpson et al.   ENDOCRINOLOGY

Increased Mitogen-Activated Protein Kinase Kinase/Extracellularly Regulated Kinase Activity in Human Endometrial Stromal Fibroblasts of Women with Endometriosis Reduces 3′,5′-Cyclic Adenosine 5′-Monophosphate Inhibition of Cyclin D1

(2009) Michael C. Velarde et al.   ENDOCRINOLOGY

Metformin Inhibits Aromatase via an Extracellular Signal-Regulated Kinase-Mediated Pathway

(2009) Suman Rice et al.   ENDOCRINOLOGY

Induction of insulin resistance by phosphatidylinositol-3-kinase inhibitor in porcine granulosa cells

(2009) Miaoe Yan et al.   FERTILITY AND STERILITY

Changes related to phosphatidylinositol 3-kinase/Akt signaling in leiomyomas: possible involvement of glycogen synthase kinase 3α and cyclin D2 in the pathophysiology

(2009) Laila Karra et al.   FERTILITY AND STERILITY

Involvement of Akt, Ras and cell cycle regulators in the potential development of endometrial hyperplasia in women with polycystic ovarian syndrome

(2009) A. Villavicencio et al.   GYNECOLOGIC ONCOLOGY

Metformin is a potent inhibitor of endometrial cancer cell proliferation—implications for a novel treatment strategy

(2009) Leigh A. Cantrell et al.   GYNECOLOGIC ONCOLOGY

Phosphatidylinositol 3-kinase p85  regulatory subunit gene Met326Ile polymorphism in women with polycystic ovary syndrome

(2009) J. J. Kim et al.   HUMAN REPRODUCTION

Expression of selected tumor suppressor and oncogenes in endometrium of women with endometriosis

(2009) P. Laudanski et al.   HUMAN REPRODUCTION

Progestins Activate the AKT Pathway in Leiomyoma Cells and Promote Survival

(2009) Anna V. Hoekstra et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Insulin Attenuates the Insulin-Like Growth Factor-I (IGF-I)-Akt Pathway, not IGF-I-Extracellularly Regulated Kinase Pathway, in Luteinized Granulosa Cells with an Increase in PTEN

(2009) Akira Iwase et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

17βE2 promotes cell proliferation in endometriosis by decreasing PTEN via NFκB-dependent pathway

(2009) Hui Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Induces Apoptosis of Human Endometriotic Cells through Suppression of ERK1/2, AKT, NFκB, and β-Catenin Pathways and Activation of Intrinsic Apoptotic Mechanisms

(2009) Sakhila K. Banu et al.   MOLECULAR ENDOCRINOLOGY

Endometriotic stromal cells lose the ability to regulate cell-survival signaling in endometrial epithelial cells in vitro

(2009) H. Zhang et al.   MOLECULAR HUMAN REPRODUCTION

Effect of Testosterone on Insulin Stimulated IRS1 Ser Phosphorylation in Primary Rat Myotubes—A Potential Model for PCOS-Related Insulin Resistance

(2009) Michael C. Allemand et al.   PLoS One

Differential regulation of Akt phosphorylation in endometriosis

(2009) Ozgur Cinar et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Luteinizing hormone-induced Akt phosphorylation and androgen production are modulated by MAP Kinase in bovine theca cells

(2009) Shin Fukuda et al.   Journal of Ovarian Research

Insulin resistance in polycystic ovary syndrome is associated with defective regulation of ERK1/2 by insulin in skeletal musclein vivo

(2008) Madhurima Rajkhowa et al.   BIOCHEMICAL JOURNAL

First Evidence of Genetic Association Between AKT2 and Polycystic Ovary Syndrome

(2008) M. O. Goodarzi et al.   DIABETES CARE

Expression of insulin-like growth factors (IGFs) and IGF signaling: molecular complexity in uterine leiomyomas

(2008) Lan Peng et al.   FERTILITY AND STERILITY

Effects of metformin and ethinyl estradiol-cyproterone acetate on clinical, endocrine and metabolic factors in women with polycystic ovary syndrome

(2008) Jie Wu et al.   GYNECOLOGICAL ENDOCRINOLOGY

A low concentration of genistein induces estrogen receptor-alpha and insulin-like growth factor-I receptor interactions and proliferation in uterine leiomyoma cells

(2008) X. Di et al.   HUMAN REPRODUCTION

Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA), a candidate gene for polycystic ovary syndrome

(2008) M.O. Goodarzi et al.   HUMAN REPRODUCTION

Unknown

(2008) Linda Yu et al.   MOLECULAR MEDICINE

Pioglitazone Enhances Mitochondrial Biogenesis and Ribosomal Protein Biosynthesis in Skeletal Muscle in Polycystic Ovary Syndrome

(2008) Vibe Skov et al.   PLoS One

Serial analysis of gene expression reveals differential expression between endometriosis and normal endometrium. Possible roles for AXL and SHC1 in the pathogenesis of endometriosis

(2008) Hiroshi Honda et al.   Reproductive Biology and Endocrinology

Estrogen receptor alpha (ERα) phospho-serine-118 is highly expressed in human uterine leiomyomas compared to matched myometrium

(2008) Tonia L. Hermon et al.   VIRCHOWS ARCHIV

Ovulatory Response to Treatment of Polycystic Ovary Syndrome Is Associated with a Polymorphism in theSTK11Gene

(2007) Richard S. Legro et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM