Article
Endocrinology & Metabolism
Xiaofang Li, Yan'e Gao, Juanzi Shi, Wenhao Shi, Haiyan Bai
Summary: In the comparison of endometrial preparation methods for single euploid frozen blastocyst transfers, natural cycles (NC) were associated with a higher live birth rate and lower total pregnancy loss compared to hormone replacement treatment (HRT). Despite the convenience of HRT, choosing NC as the endometrial preparation method may lead to a higher chance of live birth.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Ana Raquel Neves, Samuel Santos-Ribeiro, Sandra Garcia-Martinez, Marta Devesa, Sergio R. Soares, Juan Antonio Garcia-Velasco, Nicolas Garrido, Nikolaos P. Polyzos
Summary: The study found that in a freeze-all approach, there was no significant difference in euploidy rate and cumulative live birth rate between PGT-A cycles with and without late-follicular progesterone elevation.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Article
Endocrinology & Metabolism
Xinhong Yang, Zhiqin Bu, Linli Hu
Summary: The study found that in the first HRT cycle, frozen-thawed blastocyst transfer on the sixth day of progesterone administration is associated with a higher live birth rate compared to transfer on the seventh day, especially among patients under 35 years old, D5 blastocyst transfer, and/or high-quality blastocyst transfer.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Obstetrics & Gynecology
Jaimin S. Shah, Denis A. Vaughan, Laura E. Dodge, Angela Leung, Ann Korkidakis, Denny Sakkas, David A. Ryley, Alan S. Penzias, Thomas L. Toth
Summary: This study aimed to investigate the relationship between endometrial compaction and live birth rates in euploid frozen embryo transfer cycles. The results showed that there was no correlation between endometrial compaction and live birth rates in single euploid FET cycles.
HUMAN REPRODUCTION
(2022)
Article
Endocrinology & Metabolism
Rui Jia, Yuanyuan Liu, Rulan Jiang, Xuli Zhu, Liang Zhou, Peipei Chen, Mingya Cao, Zhiming Zhao
Summary: This study aimed to determine the optimal number of oocytes retrieved for patients with PCOS undergoing IVF to achieve the best CLBR and live birth after fresh embryo transfer. The study found that the number of oocytes retrieved was an independent protective factor for CLBR, with a higher CLBR observed when the number of oocytes retrieved was 15 or more. Patients with 7-16 oocytes retrieved had a greater chance of live birth after fresh embryo transfer.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Jihui Ai, Lei Jin, Yu Zheng, Peiwen Yang, Bo Huang, Xiyuan Dong
Summary: The blastocyst expansion stage, ICM grade, and TE grade are all associated with pregnancy outcomes. ICM grade is the strongest predictor of live birth. A blastocyst with stage 4-5, ICM grade A, and TE grade A/B should be given priority for single embryo transfer.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Rulan Jiang, Mingya Cao, Haomeng Hao, Rui Jia, Peipei Chen, Yuanyuan Liu, Zhiming Zhao
Summary: The follicular output rate (FORT) has significant effects on the cumulative clinical pregnancy rate (CCPR) and cumulative live birth rate (CLBR) in polycystic ovary syndrome (PCOS) patients undergoing in vitro fertilization (IVF) treatment. A higher FORT is beneficial for achieving better pregnancy outcomes, especially for patients with polycystic ovarian morphology, ovulation disorder, or hyperandrogenic manifestations.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Elisabet Clua, Ignacio Rodriguez, Gemma Arroyo, Annalisa Racca, Francisca Martinez, Nikolaos P. Polyzos
Summary: In recipients of donated oocytes, blastocyst-stage embryo transfer leads to higher clinical pregnancy rates, live birth rates, shorter time to pregnancy, and lower costs compared to cleavage-stage embryo transfer.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Obstetrics & Gynecology
Meng Wang, Lei Jin, Juanzi Shi, Yundong Mao, Cuilian Zhang, Rui Huang, Xiaoyan Liang
Summary: This study aimed to assess the effects of estradiol (E2) levels on trigger day on cumulative live birth rates (CLBRs) and pregnancy outcomes after fresh and frozen-thawed embryo transfer (FET). The results showed that CLBR increased by 10% for every 1000 pg/mL increase in E2 when E2 was <5500 pg/mL. When E2 levels were between 5500 and 13,281 pg/mL, CLBR increased by 1.8% for every 1000 pg/mL increase in E2. CLBR decreased by 3% for every 1000 pg/mL increase in E2 when E2 was >13,281 pg/mL. The live birth rate in FET cycles was highest in the group with E2 >= 5000 pg/mL.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Endocrinology & Metabolism
Xian Wu, Wen-jie Zhou, Bu-fang Xu, Qian Chen, Lan Xia, Shen Zhao, Hui-hui Xu, Ai-jun Zhang, Zhi-hong Niu
Summary: The study suggests that single good-quality blastocyst transfer is recommended for women of all ages. When good-quality cleavage embryos are available, the choice of single or double embryo transfer with good- or average-quality embryo should depend on the age of women. Double embryo transfer with the highest possible grade of embryos is recommended for women aged >= 40 years.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Junwei Zhang, Zhen Li, Lijun Sun, Yichun Guan, Mingze Du
Summary: The study compared the outcomes of different endometrial preparation methods for frozen embryo transfer (FET) cycles in patients with abnormal ovulation. It found that the low hormone replacement therapy (L-FET) regimen had a higher live birth rate and lower miscarriage rate compared to hormone replacement therapy (HRT) for these patients, with similar neonatal outcomes between the two groups.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Obstetrics & Gynecology
Adrija Kumar Datta, Stuart Campbell, Nirmal Felix, Jasdev Singh Harbhajan Singh, Geeta Nargund
Summary: For women with uncompromised ovarian reserve undergoing mild stimulation IVF, optimizing live birth rate (LBR) per cycle and cumulative LBR (CLBR) is achieved with 9 oocytes or 4 embryos for fresh transfers, and 12 oocytes or 9 embryos for predicted normal responders, while safeguarding against ovarian hyperstimulation syndrome (OHSS).
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Article
Obstetrics & Gynecology
Isabel Beshar, Jasmyn K. Johal, Brindha Bavan, Amin A. Milki
Summary: The study found that withholding doxycycline did not reduce the success rates of natural cycle frozen embryo transfers, indicating that the risks associated with antibiotics may outweigh the benefits in this context.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Jie Wang, Zhenyu Diao, Junshun Fang, Lihua Zhu, Zhipeng Xu, Fei Lin, Ningyuan Zhang, Linjun Chen
Summary: This retrospective study suggests that the day 3 embryo cell number has an influence on the clinical pregnancy and live birth rates of day 5 single blastocyst transfer in frozen embryo transfer (FET) cycles. As the day 3 embryo cell number increases, the clinical pregnancy and live birth rates also increase, especially when fair- and poor-quality blastocysts are transferred.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Endocrinology & Metabolism
Yiyang Luo, Shan Liu, Hui Su, Lin Hua, Haiying Ren, Minghui Liu, Yuting Wan, Huanhuan Li, Yuan Li
Summary: Serum LH levels have an impact on the live birth rate during ovarian stimulation cycles and after embryo transfers, with low LH levels associated with a decreased live birth rate after fresh embryo transfers.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Acoustics
Stefano Guerriero, MariaAngela Pascual, Silvia Ajossa, Manuela Neri, Monica Pilloni, Betlem Graupera, Ignacio Rodriguez, Juan Luis Alcazar
Summary: The study reveals that the reproducibility of ultrasonographic findings of rectosigmoid endometriosis among different level of expertise is moderate to very good for intra-observer agreement and fair to very good for inter-observer agreement. The typical US sign of rectosigmoid endometriosis is reasonably recognizable in stored 3D volumes by observers with varying levels of expertise.
JOURNAL OF ULTRASOUND IN MEDICINE
(2022)
Review
Obstetrics & Gynecology
Irene Garcia-Garcia, Juan Luis Alcazar, Ignacio Rodriguez, Maria Angela Pascual, Amparo Garcia-Tejedor, Stefano Guerriero
Summary: The study aimed to determine the pooled recurrence rate of benign adnexal masses/cysts after transvaginal ultrasound-guided aspiration. The results showed that aspiration with sclerotherapy had a lower recurrence rate compared to aspiration without sclerotherapy in a selected population. However, the heterogeneity of the studies and the lack of randomized controlled trials should be taken into consideration.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Elisabet Clua, Ignacio Rodriguez, Gemma Arroyo, Annalisa Racca, Francisca Martinez, Nikolaos P. Polyzos
Summary: In recipients of donated oocytes, blastocyst-stage embryo transfer leads to higher clinical pregnancy rates, live birth rates, shorter time to pregnancy, and lower costs compared to cleavage-stage embryo transfer.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Obstetrics & Gynecology
P. Garcia-Alfaro, I Rodriguez, F. R. Perez-Lopez
Summary: Handgrip strength (HGS) and dynapenia were not associated with hyperhomocysteinemia. Plasma homocysteine levels were significantly correlated with age, GFR, and creatinine.
Article
Genetics & Heredity
Lluc Coll, Monica Parriego, Beatriz Carrasco, Ignacio Rodriguez, Montserrat Boada, Buenaventura Coroleu, Nikolaos P. Polyzos, Francesca Vidal, Anna Veiga
Summary: The prevalence of embryo mosaicism in preimplantation genetic testing for aneuploidy (PGT-A) cycles is not significantly associated with the trophectoderm biopsy technique or the time to tubing. As long as standardized high quality procedures are followed, the specific approach to trophectoderm biopsy does not increase the generation of artefactual mosaicism. The study suggests that minimizing blastocyst manipulation should be the goal during biopsy procedures.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2022)
Article
Obstetrics & Gynecology
Marta Claramonte Nieto, Raquel Mula Used, Cristina Castellet Roig, Ignacio Rodriguez, Alberto Rodriguez Melcon, Bernat Serra Zantop, Pilar Prats Rodriguez
Summary: This study found that maternal age of 40 years or older is associated with an increased risk of cesarean section after induced labor at term. The main indication for cesarean delivery in older women was failed induction. However, no other adverse maternal or neonatal outcomes were found to be associated with age.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
(2022)
Article
Obstetrics & Gynecology
Pascual Garcia-Alfaro, Sandra Garcia, Ignacio Rodriguez, Luciana Bergamaschi, Faustino R. Perez-Lopez
Summary: This study aimed to evaluate the endogenous hormonal factors related to dominant handgrip strength in postmenopausal women. The results showed that there was no significant association between endogenous hormones and handgrip strength in postmenopausal women.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2023)
Article
Pathology
Manuel Sanchez-Prieto, Laura Perdomo, Berta Cortes, Ignacio Rodriguez, Pilar Prats, Alberto Rodriguez-Melcon, Pere Barri-Soldevila, Bernat Serra, Gerard Albaiges
Summary: This study evaluated the obstetrical outcomes, ultrasonographic characteristics, and final diagnosis of fetal megacystis (FM). The results showed that most FM cases were detected in the second trimester, and the majority of pregnancies were electively terminated. FM was often associated with other ultrasound abnormalities, with the most common being umbilical cord cyst. About 44% of FM cases had an identifiable cause.
FETAL AND PEDIATRIC PATHOLOGY
(2023)
Article
Endocrinology & Metabolism
A. Racca, M. Alvarez, S. Garcia Martinez, I. Rodriguez, I. Gonzalez-Foruria, N. P. Polyzos, B. Coroleu
Summary: The main objective of this study is to determine the optimal trade-off progesterone (P4) values on the day of embryo transfer (ET), identify low P4-human chorionic gonadotropin (hCG), and establish whether P4 supplementation started on the hCG day can increase the success rate of the frozen embryo transfer (FET) cycle.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Acoustics
G. Albaiges, I. Papastefanou, I. Rodriguez, P. Prats, M. Echevarria, M. A. Rodriguez, A. Rodriguez Melcon
Summary: This study examines the external validity of the new Fetal Medicine Foundation (FMF) competing-risks model for predicting small-for-gestational-age (SGA) neonates in midgestation. The study finds that the model performs well in a large independent Spanish population.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Chemistry, Physical
Claudia Vazquez Sanz, Ignacio Rodriguez, Francisco Forriol, Elena Tejado, Francisco J. Lopez-Valdes
Summary: In this study, the relationship between the mechanical properties and chemical composition of bone with age in bovine and ovine animals was investigated. Compositional analysis and nanoindentation analysis were performed on bone tissue samples. The results showed significant differences in calcium content and elastic modulus between species, but no differences within each species with development. A multiple linear regression model found several significant relationships between the elastic modulus, the decrease in phosphorus and carbon content, animal species, and development.
Article
Chemistry, Multidisciplinary
Ignacio Rodriguez, Jose Luis Izquierdo-Garcia, Ehsan Yazdanparast, David Castejon, Jesus Ruiz-Cabello
Summary: Magnetic resonance imaging (MRI) is a valuable diagnostic tool for providing detailed information about the human body. Accurate computation of relaxation time mapping is critical for clinical diagnosis and treatment planning. This article compares the performance of different algorithms, showing that the RD-NLS algorithm outperforms others in computing relaxation times in MRI, particularly for T1 maps.
APPLIED SCIENCES-BASEL
(2023)
Review
Biochemistry & Molecular Biology
Pilar Alonso-Moreno, Ignacio Rodriguez, Jose Luis Izquierdo-Garcia
Summary: Nuclear magnetic resonance (NMR)-based metabolomics is a valuable tool for identifying biomarkers and understanding metabolic changes in diseases. However, the high cost and size of traditional NMR spectrometers limit its clinical use. Benchtop NMR, a compact and low-cost alternative, has shown promise in reproducibly detecting metabolite changes associated with diseases. Further research is needed to optimize benchtop NMR for clinical applications and discover additional biomarkers for disease monitoring. Overall, benchtop NMR has the potential to revolutionize metabolomics in clinical practice.
Article
Medicine, General & Internal
Jean L. L. Browne, Maria Angela Pascual, Jorge Perez, Sulimar Salazar, Beatriz Valero, Ignacio Rodriguez, Dario Cassina, Juan Luis Alcazar, Stefano Guerriero, Betlem Graupera
Summary: This study compares the BI-RADS classification with pathology results and the results of processing images through the AI algorithm KOIOS DS(TM). The findings show that the KOIOS algorithm has a higher ratio of positive biopsies in the BI-RADS 4, 5, and 6 categories, and can help avoid unnecessary biopsies in the BI-RADS 3 category.
Article
Medicine, General & Internal
Noemie Sachs-Guedj, Buenaventura Coroleu, Maria Angela Pascual, Ignacio Rodriguez, Nikolaos Polyzos
Summary: The presence of adenomyosis has a significant negative impact on the clinical outcomes of patients undergoing frozen embryo transfer (FET), leading to higher miscarriage rates, lower clinical pregnancy rates, and lower live birth rates. The use of GnRH agonist pre-treatment does not appear to improve clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
