Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium

Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins

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Assurance of mitochondrial integrity and mammalian longevity by the p62–Keap1–Nrf2–Nqo1 cascade

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Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha

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Transcript Profiling Identifies Dynamic Gene Expression Patterns and an Important Role for Nrf2/Keap1 Pathway in the Developing Mouse Esophagus

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Long-term results of ablation with antireflux surgery for Barrett’s esophagus: a clinical and molecular biologic study

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Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins

(2011) Xin Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tight Junctions and Tissue Barriers

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Claudins: Control of Barrier Function and Regulation in Response to Oxidant Stress

(2011) Christian E. Overgaard et al.   ANTIOXIDANTS & REDOX SIGNALING

Bioavailability of Sulforaphane from Two Broccoli Sprout Beverages: Results of a Short-term, Cross-over Clinical Trial in Qidong, China

(2011) P. A. Egner et al.   Cancer Prevention Research

Durability of Radiofrequency Ablation in Barrett's Esophagus With Dysplasia

(2011) Nicholas J. Shaheen et al.   GASTROENTEROLOGY

Impact of Nrf2 on esophagus epithelium cornification

(2011) Christoph J. Wruck et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

ROS Quenching Potential of the Epidermal Cornified Cell Envelope

(2011) Wilbert P. Vermeij et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Acid modulates the squamous epithelial barrier function by modulating the localization of claudins in the superficial layers

(2011) Tadayuki Oshima et al.   LABORATORY INVESTIGATION

Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis

(2011) Cory L. Simpson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes

(2011) Pablo E. Pergola et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of the heme oxygenase-1 expression in esophagitis and esophageal cancer induced by different reflux experimental models and diethylnitrosamine

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The integrity of the esophageal mucosa. Balance between offensive and defensive mechanisms

(2010) Roy C. Orlando   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Select Heterozygous Keap1 Mutations Have a Dominant-Negative Effect on Wild-Type Keap1 In Vivo

(2010) T. Suzuki et al.   CANCER RESEARCH

Management of gastroesophageal reflux disease that does not respond well to proton pump inhibitors

(2010) Tiberiu Hershcovici et al.   CURRENT OPINION IN GASTROENTEROLOGY

After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult

(2010) Florencia Arredondo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Properties of the Neosquamous Epithelium After Radiofrequency Ablation of Barrett's Esophagus Containing Neoplasia

(2009) Roos E Pouw et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Metabolic Stress Evokes Decreases in Epithelial Barrier Function

(2009) Kimberley Lewis et al.   Annals of the New York Academy of Sciences

Evolving issues in the management of reflux disease?

(2009) Yuhong Yuan et al.   CURRENT OPINION IN GASTROENTEROLOGY

Acid and weakly acidic solutions impair mucosal integrity of distal exposed and proximal non-exposed human oesophagus

(2009) R. Farre et al.   GUT

Quercetin Enhances Intestinal Barrier Function through the Assembly of Zonnula Occludens-2, Occludin, and Claudin-1 and the Expression of Claudin-4 in Caco-2 Cells

(2009) Takuya Suzuki et al.   JOURNAL OF NUTRITION

Radiofrequency Ablation in Barrett's Esophagus with Dysplasia

(2009) Nicholas J. Shaheen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reactive nitrogen oxide species induce dilatation of the intercellular space of rat esophagus

(2009) H. Ito et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Oxidative stress induces gastric epithelial permeability through claudin-3

(2008) Kayo Hashimoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1

(2008) Claude A. Piantadosi et al.   CIRCULATION RESEARCH

Histopathology of Barrett’s esophagus after ablation and endoscopic mucosal resection therapy

(2008) R. Odze et al.   ENDOSCOPY

Effect of quercetin, flavonoids and α-tocopherol, an antioxidant vitamin on experimental reflux oesophagitis in rats

(2008) Chandana Venkateswara Rao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria

(2008) Shih-Ching Lo et al.   EXPERIMENTAL CELL RESEARCH

Mechanisms of heartburn

(2008) Daphne Ang et al.   Nature clinical practice. Gastroenterology & hepatology