Article
Gastroenterology & Hepatology
Maximilien Barret, Mathieu Pioche, Benoit Terris, Thierry Ponchon, Franck Cholet, Frank Zerbib, Edouard Chabrun, Marc Le Rhun, Emmanuel Coron, Marc Giovannini, Fabrice Caillol, Rene Laugier, Jeremie Jacques, Romain Legros, Christian Boustiere, Gabriel Rahmi, Elodie Metivier-Cesbron, Geoffroy Vanbiervliet, Paul Bauret, Jean Escourrou, Julien Branche, Lea Jilet, Hendy Abdoul, Nadira Kaddour, Sarah Leblanc, Michael Bensoussan, Frederic Prat, Stanislas Chaussade
Summary: This study found through a randomized trial that radiofrequency ablation therapy can moderately reduce the prevalence of low-grade dysplasia (LGD) in Barrett's esophagus over 3 years and decrease the risk of progression. The complication rate was highest after the first radiofrequency ablation treatment.
Article
Gastroenterology & Hepatology
Allon Kahn, Julia Crook, Michael G. Heckman, Mikolaj A. Wieczorek, Sarmed Sami, Diana Snyder, Siddharth Agarwal, Jose Santiago, Jacobo Ortiz Fernandez-Sordo, W. Keith Tan, Ramona Lansing, Kenneth K. Wang, Krish Ragunath, Massimiliano DiPietro, Herbert Wolfsen, Francisco Ramirez, David Fleischer, Cadman L. Leggett, Prasad G. Iyer
Summary: This study proposes optimal surveillance intervals after complete eradication of intestinal metaplasia (CE-IM) based on a multicenter international cohort, aiming to reduce the endoscopic burden for patients.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Oncology
Leonardo Henry Eusebi, Andrea Telese, Chiara Castellana, Rengin Melis Engin, Benjamin Norton, Apostolis Papaefthymiou, Rocco Maurizio Zagari, Rehan Haidry
Summary: Barrett's oesophagus is a pathological condition characterized by the replacement of normal oesophageal squamous mucosa with specialised, intestinal-type metaplasia, which is strongly associated with chronic gastro-oesophageal reflux. Accurate diagnosis is crucial for managing Barrett's oesophagus to identify patients at high risk of developing neoplasia and guide appropriate endoscopic therapy.
Article
Gastroenterology & Hepatology
Chetan Mittal, V. Raman Muthusamy, Violette C. Simon, Brian C. Brauer, Daniel K. Mullady, Thomas Hollander, Ian Sloan, Vladimir Kushnir, Dayna Early, Amit Rastogi, Hazem T. Hammad, Steven A. Edmundowicz, Samuel Han, Adarsh M. Thaker, Ezenwanyi Ezekwe, Sachin Wani, Mary J. Kwasny, Srinadh Komanduri
Summary: This study aimed to define the threshold of endoscopic eradication therapy (EET) sessions required to achieve complete eradication of intestinal metaplasia (CE-IM). The study found that in the majority of patients, three EET sessions can achieve CE-IM. Age and length of Barrett's esophagus were significant predictors of incomplete response.
Article
Gastroenterology & Hepatology
Linda S. Yang, Bronte A. Holt, Richard Williams, Richard Norris, Edward Tsoi, Georgina Cameron, Paul Desmond, Andrew C. F. Taylor
Summary: This study retrospectively analyzed patients with dysplastic Barrett's esophagus and found that buried Barrett's mucosa was identified in 7% of cases, even in treatment-naive patients. The proposed endoscopic features showed a diagnostic accuracy of 79% in patients with histologically confirmed disease. These features may predict the presence of buried Barrett's mucosa, which could contain dysplasia or neoplasia.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Tony He, Vijaya Sundararajan, Nicholas J. Clark, John Slavin, Edward H. Tsoi, Alexander J. Thompson, Bronte A. Holt, Paul V. Desmond, Andrew C. F. Taylor
Summary: Routine surveillance biopsy sampling of normal-appearing tubular esophageal neosquamous epithelium has no yield for detecting recurrent nondysplastic BE or dysplasia after CRIM. Dysplastic recurrences are predominantly visible and located in BE islands, while dysplastic recurrences at the gastroesophageal junction are less visible. Endoscopic features can help identify recurrent advanced dysplasia or neoplasia.
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Hiroyuki Aihara, Vladimir Kushnir, Gobind S. Anand, Lisa Cassani, Prabhleen Chahal, Sunil Dacha, Anna Duloy, Sahar Ghassemi, Christopher Huang, Thomas E. Kowalski, Emad Qayed, Sunil G. Sheth, C. Roberto Simons-Linares, Jason R. Taylor, Sarah B. Umar, Stacie A. F. Vela, Catharine M. Walsh, Renee L. Williams, Mihir S. Wagh
Summary: This document is part of a series prepared by the American Society for Gastrointestinal Endoscopy Training Committee, offering recommendations for a training curriculum focusing on endoscopic mucosal resection (EMR). It serves as an overview of favored techniques and a guide to resources for training directors, endoscopists, and trainees.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Surgery
Younghee Choe, Byung-Wook Kim, Tae Ho Kim, Jun-Won Chung, Jongwon Kim, Soo-Young Na, Joon Sung Kim
Summary: This study aimed to determine the optimal interval for surveillance gastroscopy after endoscopic resection for gastric neoplasia and investigate the risk factors for metachronous gastric neoplasia. A retrospective review of medical records identified 677 patients who underwent endoscopic resection, and it was found that severe atrophic gastritis was an independent risk factor for metachronous gastric adenocarcinoma.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Nutrition & Dietetics
Sabrina E. Wang, Allison Hodge, S. Ghazaleh Dashti, Suzanne C. Dixon-Suen, Natalia Castano-Rodriguez, Robert Thomas, Graham Giles, Alex Boussioutas, Bradley Kendall, Dallas R. English
Summary: This study found that diet is a potential modifiable risk factor for Barrett's oesophagus (BE), the precursor of oesophageal adenocarcinoma. Higher intakes of leafy vegetables, fruit, dietary fiber, and carotenoids were inversely associated with BE risk, while higher intakes of discretionary food and total fat were positively associated with BE risk. No association was found for meat, protein, dairy products, or diet scores.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Medicine, General & Internal
Adam G. Berman, W. Keith Tan, Maria O'Donovan, Florian Markowetz, Rebecca C. Fitzgerald
Summary: This study aimed to assess the diagnostic value of Cytosponge-TFF3 test in distinguishing clinically relevant Barrett's oesophagus from focal intestinal metaplasia pathologies, and to automate TFF3 counting using machine learning. The results showed that TFF3 counting could differentiate these two pathologies with high precision and accuracy. It could help minimize overdiagnosis of focal intestinal metaplasia pathologies with low cancer-associated risk.
Article
Gastroenterology & Hepatology
D. Chamil Codipilly, Lovekirat Dhaliwal, Meher Oberoi, Parth Gandhi, Michele L. Johnson, Ramona M. Lansing, W. Scott Harmsen, Kenneth K. Wang, Prasad G. Iyer
Summary: Endoscopic submucosal dissection (ESD) achieves higher complete remission rates of dysplasia in Barrett's esophagus patients compared to cap-assisted endoscopic mucosal resection (cEMR), although rates of complete remission of intestinal metaplasia (CRIM) at 2 years and complication rates are similar between the two groups.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Quinn S. Solfisburg, Sarmed S. Sami, Joel Gabre, Ali Soroush, Lovekirat Dhaliwal, Claire Beveridge, Zhezhen Jin, John M. Poneros, Gary W. Falk, Gregory G. Ginsberg, Kenneth K. Wang, Charles J. Lightdale, Prasad G. Iyer, Julian A. Abrams
Summary: Recurrence of intestinal metaplasia at the gastroesophageal junction (GEJIM) after endoscopic eradication of Barrett's esophagus (BE) is common, but not associated with an increased risk of subsequent dysplasia. Older age and longer initial BE length are independently associated with recurrence.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Alanna Ebigbo, Robert Mendel, Tobias Rueckert, Laurin Schuster, Andreas Probst, Johannes Manzeneder, Friederike Prinz, Matthias Mende, Ingo Steinbrueck, Siegbert Faiss, David Rauber, Luis A. de Souza, Joao P. Papa, Pierre H. Deprez, Tsuneo Oyama, Akiko Takahashi, Stefan Seewald, Prateek Sharma, Michael F. Byrne, Christoph Palm, Helmut Messmann
Summary: This study demonstrates the multicenter application of an AI-based system in predicting submucosal invasion in endoscopic images of Barrett's cancer. The AI system performed equally to international experts in differentiating between T1a and T1b cancer lesions, but further improvements and application are needed.
Article
Gastroenterology & Hepatology
Lady Katherine Mejia Perez, Dennis Yang, Peter Draganov, Salmaan Jawaid, Amitabh Chak, John Dumot, Omar Alaber, John J. Vargo, Sunguk Jang, Neal Mehta, Norio Fukami, Tiffany Chua, Moamen Gabr, Praneeth Kudaravalli, Hiroyuki Aihara, Fauze Maluf-Filho, Saowanee Ngamruengphong, Milad Pourmousavi Khoshknab, Amit Bhatt
Summary: The study compared the outcomes of endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) for early Barrett's esophagus neoplasia, finding that ESD had higher en bloc and R0 resection rates, lower recurrence/residual disease rates, and less need for repeat endoscopic treatments compared to EMR.
Article
Surgery
Cormac G. Magee, David Graham, Charles Gordon, Jason Dunn, Ian Penman, Robert Willert, Howard Smart, Jacobo Ortiz-Fernandez-Sordo, Krish Ragunath, Martin Everson, Durayd Alzoubaidi, Matthew Banks, Danielle Morris, Sarmed Sami, Allan J. Morris, Pradeep Bhandari, Ravi Narayanasamy, Massimiliano Di Pietro, Laurence B. Lovat, Rehan Haidry
Summary: The study demonstrates the efficacy of the 360 Express device in treating BE-related neoplasia by significantly reducing the length of lesions in a short period of time, but with a slightly higher risk of stricture formation compared to previous devices.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Marta Rodriguez-Carrasco, Eduardo Albeniz, Pradeep Bhandari, Torsten Beyna, Michael J. Bourke, Ahyeon Min, Philip W. Y. Chiu, Simon Chu, Hon Chi Yip, Pierre H. Deprez, Fabian Emura, Alessandro Repici, Noriko Suzuki, Naohisa Yahagi, Yoko Kubosawa, Cesare Hassan, Mario Dinis-Ribeiro
Summary: The lockdown period caused by the SARS-CoV-2 pandemic led to a substantial reduction in the number of endoscopic resections for neoplastic lesions. Nevertheless, based on clinical judgment, the planned median delay will not worsen the prognosis of the affected patients.
Editorial Material
Gastroenterology & Hepatology
Laurent Monino, Pierre H. Deprez, Tom G. Moreels
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Geoffroy Vanbiervliet, Marin Strijker, Marianna Arvanitakis, Arthur Aelvoet, Urban Arnelo, Torsten Beyna, Olivier Busch, Pierre H. Deprez, Lumir Kunovsky, Alberto Larghi, Gianpiero Manes, Alan Moss, Bertrand Napoleon, Manu Nayar, Enrique Perez-Cuadrado-Robles, Stefan Seewald, Marc Barthet, Jeanin E. van Hooft
Article
Gastroenterology & Hepatology
Geoffroy Vanbiervliet, Alan Moss, Marianna Arvanitakis, Urban Arnelo, Torsten Beyna, Olivier Busch, Pierre H. Deprez, Lumir Kunovsky, Alberto Larghi, Gianpiero Manes, Bertrand Napoleon, Kumanan Nalankilli, Manu Nayar, Enrique Perez-Cuadrado-Robles, Stefan Seewald, Marin Strijker, Marc Barthet, Jeanin E. van Hooft
Editorial Material
Gastroenterology & Hepatology
Laurent Monino, Rodrigo Garces-Duran, Pierre H. Deprez, Tom G. Moreels
Editorial Material
Gastroenterology & Hepatology
Carina Leal, Helene Dano, Leila Belkhir, Pierre H. Deprez
Article
Gastroenterology & Hepatology
Pierre H. Deprez, Leon M. G. Moons, Dermot O'Toole, Rodica Gincul, Andrada Seicean, Pedro Pimentel-Nunes, Gloria Fernandez-Esparrach, Marcin Polkowski, Michael Vieth, Ivan Borbath, Tom G. Moreels, Els Nieveen van Dijkum, Jean-Yves Blay, Jeanin E. van Hooft
Summary: This article provides recommendations for the characterization and management of subepithelial lesions (SELs), including the use of endoscopic ultrasonography (EUS) for characterization, tissue diagnosis for SELs with features suggestive of gastrointestinal stromal tumor (GIST), and surveillance strategies for SELs based on size and diagnosis.
Article
Gastroenterology & Hepatology
Camille Amadieu, Valentin Coste, Audrey M. Neyrinck, Victoria Thijssen, Quentin Leyrolle, Laure B. Bindels, Hubert Piessevaux, Peter Starkel, Philippe de Timary, Nathalie M. Delzenne, Sophie Leclercq
Summary: This study aims to evaluate the effects of supplementing alcohol-dependent patients with prebiotic fiber on gut microbiota and patient behavior. The results showed that prebiotics can modulate gut microbiota and improve social behavior, but had limited effects on other psychological and biological parameters.
Article
Gastroenterology & Hepatology
Florencia Carbone, Karen Van den Houte, Linde Besard, Celine Tack, Joris Arts, Philip Caenepeel, Hubert Piessevaux, Alain Vandenberghe, Christophe Matthys, Jessica Biesiekierski, Luc Capiau, Steven Ceulemans, Olivier Gernay, Lydia Jones, Sophie Maes, Christian Peetermans, Willem Raat, Jeroen Stubbe, Rudy Van Boxstael, Olivia Vandeput, Sophie Van Steenbergen, Lukas Van Oudenhove, Tim Vanuytsel, Michael Jones, Jan Tack
Summary: This study investigated the effects of a FODMAP-lowering diet application versus a spasmolytic agent in improving symptoms of IBS in primary care. The results showed that the FODMAP-lowering diet application was superior to the spasmolytic agent in improving IBS symptoms, suggesting it should be considered as the first-line treatment for IBS in primary care.
Article
Gastroenterology & Hepatology
Florencia Carbone, Alain Vandenberghe, Lieselot Holvoet, Hubert Piessevaux, Joris Arts, Philippe Caenepeel, Dirk Staessen, Philippe Vergauwe, Philippe Maldague, Thierry De Ronde, Fabien Wuestenberghs, Vincent Lamy, Veronique Lefebvre, Pascale Latour, Tim Vanuytsel, Michael Jones, Jan Tack
Summary: This study aimed to evaluate the therapeutic effect of itopride on functional dyspepsia. The results showed that itopride could improve symptoms, especially in patients with epigastric pain syndrome.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Review
Gastroenterology & Hepatology
Diogo Libanio, Pedro Pimentel-Nunes, Barbara Bastiaansen, Raf Bisschops, Michael. J. J. Bourke, Pierre. H. H. Deprez, Gianluca Esposito, Arnaud Lemmers, Philippe Leclercq, Roberta Maselli, Helmut Messmann, Oliver Pech, Mathieu Pioche, Michael Vieth, Bas L. A. M. Weusten, Lorenzo Fuccio, Pradeep Bhandari, Mario Dinis-Ribeiro
Summary: ESGE suggests conventional endoscopic submucosal dissection (ESD) for most esophageal and gastric lesions. Tunneling ESD is recommended for esophageal lesions involving more than two-thirds of the esophageal circumference. The pocket-creation method is recommended for colorectal ESD, especially without traction devices. The use of appropriate ESD knives, submucosal injection solutions, and traction methods is also recommended. Coagulation of visible vessels, post-procedure medication, and closure of ESD defects are recommended in specific situations.
Article
Gastroenterology & Hepatology
Mathilde Simonnot, Pierre H. Deprez, Mathieu Pioche, Eliane Albuisson, Timothee Wallenhorst, Fabrice Caillol, Stephane Koch, Emmanuel Coron, Isabelle Archambeaud, Jeremie Jacques, Paul Basile, Ludovic Caillo, Thibault Degand, Vincent Lepilliez, Philippe Grandval, Adrian Culetto, Geoffroy Vanbiervliet, Marine Camus Duboc, Olivier Gronier, Carina Leal, Jeremie Albouys, Jean-Baptiste Chevaux, Maximilien Barret, Marion Schaefer
Summary: The study aimed to evaluate the safety and efficacy of endoscopic resection for early esophageal neoplasia in patients with cirrhosis or portal hypertension. The results showed that endoscopic resection was effective and safe for these patients, and the choice of resection technique should be made in expert centers following European Society of Gastrointestinal Endoscopy guidelines.
Article
Gastroenterology & Hepatology
F. C. Della Casa, L. Monino, P. H. Deprez, A. Steyaert, Ph. Pendeville, H. Piessevaux, T. G. Moreels
Summary: The study aimed to track all adverse events (AE) during endoscopic procedures using voluntary reporting and retrospective data analysis. The results showed that while voluntary reporting of AE was unreliable, systematic registration of AE was feasible with some challenges and time-consuming process. Therefore, more practical methods are needed to obtain reliable and long-term data.
ACTA GASTRO-ENTEROLOGICA BELGICA
(2022)
Article
Gastroenterology & Hepatology
S. Kindt, H. Louis, H. De Schepper, J. Arts, P. Caenepeel, D. De Looze, A. Gerkens, T. Holvoet, P. Latour, T. Mahler, F. Mokaddem, S. Nullens, H. Piessevaux, P. Poortmans, G. Rasschaert, M. Surmont, H. Vafa, K. Van Malderen, T. Vanuytsel, F. Wuestenberghs, J. Tack
Summary: A Delphi consensus conducted by Belgian experts on irritable bowel syndrome (IBS) reached agreement on several key statements, such as the multifactorial etiology of IBS, the importance of subtyping based on stool pattern, and the necessity of a positive diagnosis relying on history and clinical examination. The consensus also highlighted the significance of patient education and management, as well as the appropriate use of lifestyle modification, spasmolytics, and specific treatments for diarrhea and constipation. However, faecal microbiota transplantation and gluten removal were considered to be restricted.
ACTA GASTRO-ENTEROLOGICA BELGICA
(2022)
Article
Gastroenterology & Hepatology
C. Dumont, F. Wuestenberghs, N. Lanthier, H. Piessevaux, G. Dahlqvist
Summary: Malnutrition is highly prevalent in hospitalized cirrhotic patients and is associated with poor outcomes. Malnutrition, low prognostic nutritional index, and low Braden scale are related to a worse prognosis in cirrhosis.
ACTA GASTRO-ENTEROLOGICA BELGICA
(2022)