Microwave-assisted hydrolysis of phosphonate diesters: an efficient protocol for the preparation of phosphonic acids

The clinical potential of the acyclic (and cyclic) nucleoside phosphonates. The magic of the phosphonate bond

(2011) Erik De Clercq   BIOCHEMICAL PHARMACOLOGY

Synthesis and antiviral activity of N9-[3-fluoro-2-(phosphonomethoxy)propyl] analogues derived from N6-substituted adenines and 2,6-diaminopurines

(2011) Ondřej Baszczyňski et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: Evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine–guanine–(xanthine) phosphoribosyltransferases

(2011) Michal Česnek et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Review on Modern Advances of Chemical Methods for the Introduction of a Phosphonic Acid Group

(2011) Charles S. Demmer et al.   CHEMICAL REVIEWS

6-Oxopurine Phosphoribosyltransferase: A Target for the Development of Antimalarial Drugs

(2011) John de Jersey et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities

(2011) Petr Jansa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Efficient and ‘green’ microwave-assisted synthesis of haloalkylphosphonates via the Michaelis–Arbuzov reaction

(2011) Petr Jansa et al.   GREEN CHEMISTRY

A critical assessment of the greenness and energy efficiency of microwave-assisted organic synthesis

(2011) Jonathan D. Moseley et al.   GREEN CHEMISTRY

Synthesis of 3,3-Bis(diethylphosphono)-1-(3H)-isobenzofuranone and Its Chemical Properties

(2011) Viacheslav N. Zemlianoy et al.   PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS

An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids

(2011) Petr Jansa et al.   TETRAHEDRON

An efficient oxa-Michael addition to diethyl vinylphosphonate under mild reaction conditions

(2011) Ondřej Baszczyňski et al.   RSC Advances

Structural-based design and synthesis of novel 9-deazaguanine derivatives having a phosphate mimic as multi-substrate analogue inhibitors for mammalian PNPs

(2010) Sadao Hikishima et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase

(2010) Joris W. De Schutter et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure–activity relationships of tulipalines, tuliposides, and related compounds as inhibitors of MurA

(2010) Thomas Mendgen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Properties of a Novel Type of Acyclic Nucleoside Phosphonates: 2-(Purin-9-yl)ethoxyphenylphosphonic Acids

(2010) Dana Hocková et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis, Chiral High Performance Liquid Chromatographic Resolution and Enantiospecific Activity of a Potent New Geranylgeranyl Transferase Inhibitor, 2-Hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic Acid

(2010) Charles E. McKenna et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Virtual Screening Hit Reveals New Possibilities for Developing Group III Metabotropic Glutamate Receptor Agonists

(2010) Chelliah Selvam et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective Rh-Catalyzed Hydrogenation of 3-Aryl-4-phosphonobutenoates with aP-Stereogenic BoPhoz-Type Ligand

(2010) Zheng-Chao Duan et al.   JOURNAL OF ORGANIC CHEMISTRY

Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position

(2009) Marcela Krečmerová et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chiral analysis of anti-acquired immunodeficiency syndrome drug, 9-(R)-[2-(phosphonomethoxy)propyl]adenine (tenofovir), and related antiviral acyclic nucleoside phosphonates by CE using β-CD as chiral selector

(2009) Veronika Šolínová et al.   ELECTROPHORESIS

Methyl 4-toluenesulfonyloxymethylphosphonate, a new and versatile reagent for the convenient synthesis of phosphonate-containing compounds

(2009) Ivana Kóšiová et al.   TETRAHEDRON LETTERS

Microwave dielectric heating in synthetic organic chemistry

(2008) C. Oliver Kappe   CHEMICAL SOCIETY REVIEWS

Acyclic nucleoside bisphosphonates: Synthesis and properties of chiral 2-amino-4,6-bis[(phosphonomethoxy)alkoxy]pyrimidines

(2008) Petra Doláková et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Prodrugs of Phosphates and Phosphonates

(2008) Scott J. Hecker et al.   JOURNAL OF MEDICINAL CHEMISTRY