Article
Medicine, General & Internal
Youssef Abdelmassih, Georges Azar, Sophie Bonnin, Claire Scemama Timsit, Vivien Vasseur, Richard F. Spaide, Francine Behar-Cohen, Martine Mauget-Faysse
Summary: ICGA and OCT findings revealed anomalies in retinal and choroidal vasculature in patients hospitalized for severe COVID infection, possibly related to the SARS-CoV2 virus.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Pharmacology & Pharmacy
Lei Jiao, Chaoran Lv, Hongling Zhang
Summary: This study explores the relationship between blood pressure variability (BPV) levels and the use of optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) to measure retinal microvasculature in hypertensive patients. The findings suggest that hypertensive retinopathy is associated with BPV and factors such as disease duration, age, and blood pressure variability affect retinal thickness and vascular density.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2023)
Article
Medicine, General & Internal
Aniruddha Agarwal, Sabia Handa, Alessandro Marchese, Salvatore Parrulli, Alessandro Invernizzi, Roel J. Erckens, Tos T. J. M. Berendschot, C. A. B. Webers, Reema Bansal, Vishali Gupta
Summary: This study analyzed OCT findings in PIC eyes suggestive of CNV, showing that quantitative and qualitative OCT analysis can help predict the presence of CNV in these eyes. Lesions with CNV+ had larger dimensions and distinct features compared to CNV- lesions.
FRONTIERS IN MEDICINE
(2021)
Article
Optics
Zhenhe Ma, Ning Ding, Zhen Li, Keliang Zhu, Ang Li, Zhanhong Lin, Yi Wang, Yuqian Zhao, Yao Yu, Jingmin Luan, Xin Zhu, Jian Liu
Summary: This article introduces a method to extract the photoacoustic (PA) signal from the contrast reduction in the interference spectrum obtained from spectral domain optical coherence tomography (SDOCT). The method utilizes the specular reflection on the water surface to achieve all-optical detection in a non-contact manner. By analyzing the phase changes in the interference spectrum induced by water surface vibration, the method enables quantification of the interference contrast reduction for PA imaging.
Article
Optics
Yuye Ling, Zhenxing Dong, Xueshen Li, Yu Gan, Yikai Su
Summary: With the advancement of light source technology, the A-line imaging rate of SS-OCT has significantly increased in the past three decades. However, the bandwidths of data acquisition, transfer, and storage have become major limitations in modern SS-OCT system design. To address this, a novel design paradigm is proposed where the sub-sampling pattern for interferogram acquisition is jointly optimized with the reconstruction algorithm. This method achieves high data compression ratios without impairing image quality, making it a potential solution for the data issue in SS-OCT.
Article
Optics
Tanbin Shao, Kecheng Yang, Min Xia, Wenping Guo
Summary: In this study, an enhanced dispersion-encoded full-range spectral interferometry technique is proposed and validated for improving measurement accuracy in samples with significant depth, inclination, and roughness. By removing the direct current and preserving data with good phase continuity, the accuracy of phase compensation is improved. The proposed technique extends the depth measurement range and achieves high axial measurement precision.
Review
Biochemistry & Molecular Biology
Luca Scuderi, Serena Fragiotta, Mariachiara Di Pippo, Solmaz Abdolrahimzadeh
Summary: Diabetic choroidopathy refers to the accumulation of PAS-positive material in the tissue of diabetic eyes. Inflammation and activation of neutrophils are crucial factors in the impairment of choriocapillaris. The presence of diabetic choroidopathy in vivo has been confirmed with multimodal imaging, which provides important qualitative and quantitative features to characterize the involvement of choroid.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Medicine, General & Internal
Lisa Toto, Maria Ludovica Ruggeri, Federica Evangelista, Chiara Trivigno, Rossella D'Aloisio, Chiara De Nicola, Pasquale Viggiano, Emanuele Doronzo, Marta Di Nicola, Annamaria Porreca, Rodolfo Mastropasqua
Summary: This study investigates the parameters of optical coherence tomography (OCT) and OCT angiography (OCTA) in patients with neovascular age-related macular degeneration (nAMD) and macular neovascularization (MNV) types 1, 2, and 3. The results showed significant differences in CVI, CMT, and ORCCFA between MNV 1 and the other two groups. CVI was significantly different between MNV 1 and healthy controls and between MNV 1 and MNV 2. ORCCFA and CMT were significantly different between MNV 1 and MNV 2. There was no statistically significant difference in subfoveal choroidal thickness (SFCT) among the three groups.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Chen Huang, Keren Xie, Yuhan Zhang, Mingchao Li, Songtao Yuan, Qiang Chen
Summary: The proposed fusion method combining SD-OCT and OCTA images is more effective for CNV visualization, providing a satisfying visual effect by integrating complementary information from multimodal images.
Article
Engineering, Electrical & Electronic
Prabhav Gaur, Andrew Grieco, Yeshaiahu Fainman
Summary: This article presents a method to improve the performance of spectral domain optical coherence tomography by using phase modulators and delay lines as filters, scanning multiple channels and combining them in a digital computer.
IEEE PHOTONICS JOURNAL
(2023)
Article
Chemistry, Analytical
Hong-Yan Zheng, Bo-Liang Chen, Hsiao-Yen Lu, Shih-Hsiang Hsu, Masanori Takabayashi
Summary: A chip-based SD-OCT system utilizes a MZDC structure and an echelle grating for improving signal-to-noise ratios, wavelength response, axial resolution, and sensitivity.
Article
Multidisciplinary Sciences
Lei Shao, Ling Xiao Zhou, Liang Xu, Wen Bin Wei
Summary: The Beijing Eye Study 2011 found that in cases of hypertension, patients with hypertensive retinopathy had significantly thicker subfoveal choroidal thickness, which was significantly associated with the stage of hypertensive retinopathy. However, subfoveal choroidal thickness was not significantly associated with diastolic blood pressure, history of hypertension, or years of hypertension.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Haidong Li, Lifeng Chen, Meng'ai Wu, Bin Zheng
Summary: This study investigated the characteristics of cystic retinal tufts (CRTs) using widefield spectral-domain optical coherence tomography. The results showed that CRTs exhibited hyperreflective irregular elevated lesions with internal hyporeflective cystoid cavities on SD-OCT images. Widefield SD-OCT imaging provides detailed anatomical information and may guide clinical treatment.
Article
Optics
Dong Yang, Zhongming Yang, Yanfeng Zhang
Summary: This paper proposes and demonstrates a nano-displacement measurement system based on WSI-OAM, which features compact size and easy alignment. It achieves high accuracy and linearity with a resolution of 0.1 nm and an uncertainty of 0.013 nm for measuring nanoscale displacements.
Article
Multidisciplinary Sciences
Min-Su Kim, Ki-Yup Nam, Young Hoon Hwang, Min-Woo Lee, Woo-Hyuk Lee, Hyung-Bin Lim, Jung-Yeul Kim
Summary: It was found that Weiss ring located near the optic disc can affect the measurement of peripapillary retinal nerve fiber layer (pRNFL) thickness, especially in the inferior quadrant and average values. Therefore, it is important to consider the presence of Weiss ring when analyzing pRNFL thickness.
SCIENTIFIC REPORTS
(2022)
Review
Cardiac & Cardiovascular Systems
Mitsuaki Isobe, Koichi Amano, Yoshihiro Arimura, Akihiro Ishizu, Shuichi Ito, Shinya Kaname, Shigeto Kobayashi, Yoshinori Komagata, Issei Komuro, Kimihiro Komori, Kei Takahashi, Kazuo Tanemoto, Hitoshi Hasegawa, Masayoshi Harigai, Shouichi Fujimoto, Tatsuhiko Miyazaki, Tetsuro Miyata, Hidehiro Yamada, Akitoshi Yoshida, Takashi Wada, Yoshinori Inoue, Haruhito A. Uchida, Hideki Ota, Takahiro Okazaki, Mitsuho Onimaru, Tamihiro Kawakami, Reiko Kinouchi, Atsushi Kurata, Hisanori Kosuge, Ken-ei Sada, Kunihiro Shigematsu, Eiichi Suematsu, Eijun Sueyoshi, Takahiko Sugihara, Hitoshi Sugiyama, Mitsuhiro Takeno, Naoto Tamura, Michi Tsutsumino, Hiroaki Dobashi, Yoshikazu Nakaoka, Kenji Nagasaka, Yasuhiro Maejima, Hajime Yoshifuji, Yoshiko Watanabe, Shoichi Ozaki, Takeshi Kimura, Hiroshi Shigematsu, Keiko Yamauchi-Takihara, Toyoaki Murohara, Shin-ichi Momomura
CIRCULATION JOURNAL
(2020)
Article
Ophthalmology
Takafumi Yoshioka, Youngseok Song, Motofumi Kawai, Tomofumi Tani, Kengo Takahashi, Satoshi Ishiko, Fabio Lavinsky, Gadi Wollstein, Hiroshi Ishikawa, Joel S. Schuman, Akitoshi Yoshida
Summary: In NTG eyes with single-hemifield damage, the RBF was significantly reduced in the damaged hemisphere compared with the normal one. The RBF decreased in the normal and damaged hemispheres of NTG eyes compared with the healthy hemisphere independent from RNFLT.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Medicine, General & Internal
Kengo Takahashi, Youngseok Song, Kenji Sogawa, Takafumi Yoshioka, Tomofumi Tani, Satoshi Ishiko, Akitoshi Yoshida
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Multidisciplinary Sciences
Reiko Kinouchi, Satoshi Ishiko, Kazuomi Hanada, Hiroki Hayashi, Daiki Mikami, Akitoshi Yoshida
Summary: The study found that self-reported diabetes mellitus was a significant risk factor for retinal vascular events in both men and women, while higher systolic blood pressure and lower frequency of meat consumption were associated with the events in men. In women, self-reported hypertension was linked to retinal vascular events, but not with systolic blood pressure. Women with hypertension may require extra care beyond blood pressure management.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Satoshi Ishiko, Hiroyuki Kagokawa, Noriko Nishikawa, Youngseok Song, Kazuhiro Sugawara, Hiroaki Nakagawa, Yuichiro Kawamura, Akitoshi Yoshida
Summary: The study found that after Japan implemented a low-pressure education policy, the correlation between ophthalmic indicators and high myopia significantly decreased, and the prevalence rate of high myopia also decreased significantly. Compared to the enforcement of high-pressure education, there were significant differences in ophthalmic indicators and the prevalence rate of high myopia under the two educational approaches.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Mitsuru Otsubo, Reiko Kinouchi, Takayuki Kamiya, Akitoshi Yoshida
Summary: Two cases of taxane-related cystoid macular edema were successfully treated with topical dorzolamide, leading to the resolution of edema and improvement in visual acuity without any side effects. This treatment option appears to be safe and effective for patients with taxane-related cystoid macular edema.
JOURNAL OF MEDICAL CASE REPORTS
(2021)
Article
Chemistry, Medicinal
Miki Sato-Akushichi, Shinji Ono, Gerd Klose, Youngseok Song
Summary: This study evaluated the changes in choroidal volume and thickness after PDT treatment in patients with chronic CSC, showing a significant decrease in choroidal volume in the non-irradiated area after treatment. The algorithm provided on the ARI Network allows for quantitative and qualitative evaluation of choroidal changes.
Article
Medicine, General & Internal
Miki Sato-Akushichi, Reiko Kinouchi, Naoko Kawai, Kenichiro Nomura
Summary: This case presents optic neuropathy with hypertrophic pachymeningitis related to antineutrophil cytoplasmic antibody-associated vasculitis, suspected to be drug related. The patient experienced good visual recovery after quitting the drug and receiving immunosuppressive therapy with systemic steroids. This highlights the importance of considering antineutrophil cytoplasmic antibody-associated vasculitis related to antithyroid drugs as a differential diagnosis for optic neuropathy in Graves' patients.
JOURNAL OF MEDICAL CASE REPORTS
(2021)
Article
Chemistry, Medicinal
Miki Sato-Akushichi, Shinji Ono, Tatsuro Taneda, Gerd Klose, Asuka Sasamori, Youngseok Song
Summary: This paper evaluates the one-year treatment outcome of full or reduced photodynamic therapy (PDT) and anti-vascular endothelial growth factor (VEGF) combination therapy for pachychoroid neovasculopathy (PNV). The results showed that both full and reduced treatment reduced central retinal thickness and central choroidal thickness, and these improvements were maintained for one year after the initial combination therapy. The recurrence rate was similar between full and reduced treatment. One shot of anti-VEGF and full or reduced PDT combination therapy had similar efficacy in treating PNV. More prospective, large-scale, and long-term studies are needed to determine a better treatment for PNV.
Correction
Chemistry, Medicinal
Miki Sato-Akushichi, Shinji Ono, Gerd Klose, Youngseok Song
Article
Ophthalmology
Rui Fushitsu, Akihiro Ishibazawa, Masataka Murono, Reiko Kinouchi
Summary: This study retrospectively reviewed the outcomes of intravenous corticosteroid pulse treatment in patients with acute VKH disease. The majority of patients showed good visual outcomes, including those with persistent or worsening inflammation. Pre-existing conditions explained the low visual outcomes in most eyes.
INTERNATIONAL OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Miki Sato-Akushichi, Reiko Kinouchi, Satoshi Ishiko, Kazuomi Hanada, Hiroki Hayashi, Daiki Mikami, Shinji Ono, Yasuo Yanagi
Summary: This study aimed to investigate the prevalence and 5-year changes of soft drusen, pseudodrusen, and pachydrusen in a Japanese population. The results showed that the prevalence of pachydrusen was higher than that of soft drusen and pseudodrusen combined, and pachydrusen may regress over time without causing retinal pigment epithelium atrophy.
OPHTHALMOLOGY SCIENCE
(2021)
Letter
Dermatology
Mai Ueda-Komatsu, Mari Kishibe, Mizue Fujii, Reiko Kinouchi, Akemi Ishida-Yamamoto
EUROPEAN JOURNAL OF DERMATOLOGY
(2021)
Article
Ophthalmology
Youngseok Song, Yih-Chung Tham, Crystal Chong, Ricardo Ong, Beau J. Fenner, Kai Xiong Cheong, Kengo Takahashi, Janice Marie Jordan-Yu, Kelvin Yi Chong Teo, Anna C. S. Tan, Ching-Yu Cheng, Tien Yin Wong, Usha Chakravarthy, Yasuo Yanagi, Gemmy Chui Ming Cheung
Summary: This study aimed to describe the distribution and determinants of choroidal thickness in a population study based on spectral-domain (SD)-OCT measurements. Results showed that subfoveal choroidal thickness is influenced by age, gender, and ethnicity along with regional differences even within individual eyes. These findings may serve as a reference for future studies.
OPHTHALMOLOGY RETINA
(2021)
Article
Ophthalmology
Takanari Wada, Youngseok Song, Tsuneaki Oomae, Kenji Sogawa, Takafumi Yoshioka, Seigo Nakabayashi, Kengo Takahashi, Tomofumi Tani, Akihiro Ishibazawa, Satoshi Ishiko, Akitoshi Yoshida
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2020)