The significance of the complement system for the pathogenesis of age-related macular degeneration — current evidence and translation into clinical application
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Title
The significance of the complement system for the pathogenesis of age-related macular degeneration — current evidence and translation into clinical application
Authors
Keywords
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Journal
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
Volume 249, Issue 2, Pages 163-174
Publisher
Springer Nature
Online
2010-12-02
DOI
10.1007/s00417-010-1568-6
References
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Note: Only part of the references are listed.- Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina
- (2010) Simon J. Clark et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The molecular genetic basis of age-related macular degeneration: an overview
- (2010) Saritha Katta et al. JOURNAL OF GENETICS
- Quantitative Proteomics: Comparison of the Macular Bruch Membrane/Choroid Complex from Age-related Macular Degeneration and Normal Eyes
- (2010) Xianglin Yuan et al. MOLECULAR & CELLULAR PROTEOMICS
- A Hapten Generated from an Oxidation Fragment of Docosahexaenoic Acid Is Sufficient to Initiate Age-Related Macular Degeneration
- (2010) Joe G. Hollyfield et al. MOLECULAR NEUROBIOLOGY
- Three Major Loci Involved in Age-Related Macular Degeneration Are Also Associated with Polypoidal Choroidal Vasculopathy
- (2010) Luiz H. Lima et al. OPHTHALMOLOGY
- Progression of Geographic Atrophy and Genotype in Age-Related Macular Degeneration
- (2010) Michael L. Klein et al. OPHTHALMOLOGY
- Structure-Function Correlation of the Human Central Retina
- (2010) Peter Charbel Issa et al. PLoS One
- Comprehensive Analysis of Complement Factor H and LOC387715/ARMS2/HTRA1 Variants With Respect to Phenotype in Advanced Age-Related Macular Degeneration
- (2009) Michael T. Andreoli et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Unraveling a Multifactorial Late-Onset Disease: From Genetic Susceptibility to Disease Mechanisms for Age-Related Macular Degeneration
- (2009) Anand Swaroop et al. Annual Review of Genomics and Human Genetics
- Complement and its role in innate and adaptive immune responses
- (2009) Jason R Dunkelberger et al. CELL RESEARCH
- Support for the involvement of complement factor I in age-related macular degeneration
- (2009) Sarah Ennis et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Genetic control of the alternative pathway of complement in humans and age-related macular degeneration
- (2009) Laura A. Hecker et al. HUMAN MOLECULAR GENETICS
- The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity
- (2009) A. Tortajada et al. HUMAN MOLECULAR GENETICS
- Complement and immune defense: From innate immunity to human diseases
- (2009) Peter F. Zipfel IMMUNOLOGY LETTERS
- Rapid and Sensitive Method for Detection of Y402, H402, I62, and V62 Variants of Complement Factor H in Human Plasma Samples Using Mass Spectrometry
- (2009) U. Kelly et al. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
- Oxidative Stress Renders Retinal Pigment Epithelial Cells Susceptible to Complement-mediated Injury
- (2009) Joshua M. Thurman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The spectrum of phenotypes caused by variants in the CFH gene
- (2009) Camiel J.F. Boon et al. MOLECULAR IMMUNOLOGY
- Therapeutic potential of complement modulation
- (2009) Eric Wagner et al. NATURE REVIEWS DRUG DISCOVERY
- Coding Variant I62V in the Complement Factor H Gene Is Strongly Associated with Polypoidal Choroidal Vasculopathy
- (2009) Naoshi Kondo et al. OPHTHALMOLOGY
- Complement Factor H Y402H and C-Reactive Protein Polymorphism and Photodynamic Therapy Response in Age-Related Macular Degeneration
- (2009) Xuefeng Feng et al. OPHTHALMOLOGY
- Changes in Retinal Pigment Epithelium Related to Cigarette Smoke: Possible Relevance to Smoking as a Risk Factor for Age-Related Macular Degeneration
- (2009) Ai Ling Wang et al. PLoS One
- CFH, C3 and ARMS2 Are Significant Risk Loci for Susceptibility but Not for Disease Progression of Geographic Atrophy Due to AMD
- (2009) Hendrik P. N. Scholl et al. PLoS One
- Polypoidal choroidal vasculopathy and neovascular age-related macular degeneration: Same or different disease?
- (2009) Augustinus Laude et al. PROGRESS IN RETINAL AND EYE RESEARCH
- The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
- (2009) Don H. Anderson et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Combined Effects of Complement Factor H Genotypes, Fish Consumption, and Inflammatory Markers on Long-Term Risk for Age-related Macular Degeneration in a Cohort
- (2008) J. J. Wang et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Basal Laminar Drusen Caused by Compound Heterozygous Variants in the CFH Gene
- (2008) Camiel J.F. Boon et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Dietary ω-3 Fatty Acid and Fish Intake in the Primary Prevention of Age-Related Macular Degeneration
- (2008) Elaine W-T. Chong ARCHIVES OF OPHTHALMOLOGY
- Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab
- (2008) A Y Lee et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Variation near complement factor I is associated with risk of advanced AMD
- (2008) Jesen A Fagerness et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Up-regulation of complement factor B in retinal pigment epithelial cells is accompanied by complement activation in the aged retina
- (2008) Mei Chen et al. EXPERIMENTAL EYE RESEARCH
- Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to photodynamic therapy
- (2008) M A Brantley et al. EYE
- C3 R102G polymorphism increases risk of age-related macular degeneration
- (2008) K. L. Spencer et al. HUMAN MOLECULAR GENETICS
- Gene-environment interaction in progression of AMD: the CFH gene, smoking and exposure to chronic infection
- (2008) P. N. Baird et al. HUMAN MOLECULAR GENETICS
- Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss
- (2008) P J Francis et al. JOURNAL OF MEDICAL GENETICS
- Age-related macular degeneration
- (2008) Hanna R Coleman et al. LANCET
- Age-Related Macular Degeneration
- (2008) Rama D. Jager et al. NEW ENGLAND JOURNAL OF MEDICINE
- Age-related Macular Degeneration and Complement Activation–related Diseases
- (2008) Dorothea Nitsch et al. OPHTHALMOLOGY
- CFH and LOC387715/ARMS2 Genotypes and Treatment with Antioxidants and Zinc for Age-Related Macular Degeneration
- (2008) Michael L. Klein et al. OPHTHALMOLOGY
- The Aged Retinal Pigment Epithelium/Choroid: A Potential Substratum for the Pathogenesis of Age-Related Macular Degeneration
- (2008) Huiyi Chen et al. PLoS One
- C2 and CFB Genes in Age-Related Maculopathy and Joint Action with CFH and LOC387715 Genes
- (2008) Johanna Jakobsdottir et al. PLoS One
- Systemic Complement Activation in Age-Related Macular Degeneration
- (2008) Hendrik P. N. Scholl et al. PLoS One
- Molecular pathology of age-related macular degeneration
- (2008) Xiaoyan Ding et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Familial aggregation of age-related macular degeneration in the Utah population
- (2008) Ling Luo et al. VISION RESEARCH
- Peripheral Reticular Pigmentary Change Is Associated with Complement Factor H Polymorphism (Y402H) in Age-Related Macular Degeneration
- (2007) R. Keith Shuler et al. OPHTHALMOLOGY
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