Article
Neurosciences
Aleksandra Parka, Christiane Volbracht, Benjamin Hall, Jesper F. Bastlund, Maiken Nedergaard, Bettina Laursen, Paolo Botta, Florence Sotty
Summary: This study evaluated the association between visual function and tau pathology in a mouse model. The results showed that changes in visual evoked potential responses were observed in young mice with early tau pathology before neurodegeneration. These functional alterations were positively correlated with pathological tau levels.
JOURNAL OF ALZHEIMERS DISEASE
(2023)
Article
Engineering, Biomedical
Haoyin Xu, Sheng-Hsiou Hsu, Masaki Nakanishi, Yufan Lin, Tzyy-Ping Jung, Gert Cauwenberghs
Summary: Visual stimuli design in brain-computer interfaces based on visual evoked potentials (VEPs) plays a crucial role. This study comprehensively compared different combinations of stimulus parameters and their impact on decoding accuracy and subject comfort. The results revealed a trade-off relationship between decoding accuracy and subjective comfort level, with code-modulated VEPs (c-VEPs) being recommended for achieving reliable decoding accuracy while maintaining a reasonable level of comfortability.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Article
Psychology, Developmental
Paige M. Siper, Mikaela A. Rowe, Sylvia B. Guillory, Audrey A. Rouhandeh, Julia L. George-Jones, Teresa Tavassoli, Stacey Lurie, Jessica Zweifach, Jordana Weissman, Jennifer Foss-Feig, Danielle Halpern, M. Pilar Trelles, Maureen S. Mulhern, Chloe Brittenham, James Gordon, Vance Zemon, Joseph D. Buxbaum, Alexander Kolevzon
Summary: This study examined excitatory and inhibitory postsynaptic activity in children with Phelan-McDermid syndrome (PMS) using visual evoked potentials (VEPs) and explored the association with genetic factors. The results showed distinct VEP waveform abnormalities in children with PMS, which might reflect underlying glutamatergic deficits associated with deletion size. VEPs offer a noninvasive measure that holds promise for clinical trials in PMS and ASD.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2022)
Article
Biochemistry & Molecular Biology
Nan Su, Weiqi Zhang, Nicole Eter, Peter Heiduschka, Mingyue Zhang
Summary: Schizophrenia is associated with abnormalities in visual processes, and abnormal Nrg1 expression has been observed in clinical studies. This study investigated the effects of Nrg1 overexpression on visual function in transgenic mice. The results showed that Nrg1 overexpression changed visual function, suggesting its potential as a biomarker for psychiatric disorders and a tool for diagnosis in psychiatry.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biology
Jingjing Zang, Matthias Gesemann, Jennifer Keim, Marijana Samardzija, Christian Grimm, Stephan C. F. Neuhauss
Summary: The study found that the circadian rhythm influences the expression and function of visual transduction cascade regulators in diurnal zebrafish and nocturnal mice, impacting their visual abilities and photoresponse kinetics. Additionally, the rhythmicity of these regulators persists in continuous darkness and is disrupted by an inverted light cycle and constant light exposure.
Article
Clinical Neurology
Satoshi Kawajiri, Makoto Isozaki, Osamu Komori, Shinsuke Yamada, Yorhifumi Higashino, Takahiro Yamauchi, Ayumi Akazawa, Masamune Kidoguchi, Munetaka Yomo, Toshiaki Kodera, Hidetaka Arishma, Kousuke Awara, Masaru Inatani, Kenichiro Kikuta
Summary: This study found that intraoperative neuromonitoring with VEP can predict deterioration of visual function after direct clipping of the paraclinoid ICA aneurysm.
Article
Clinical Neurology
Thomas J. Covey, Daniel Golan, Glen M. Doniger, Robert Sergott, Myassar Zarif, Jared Srinivasan, Barbara Bumstead, Jeffrey Wilken, Marijean Buhse, Samson Mebrahtu, Mark Gudesblatt
Summary: This study found a significant association between prolonged VEP latency and poorer cognitive performance in people with multiple sclerosis, indicating that delayed VEP latency is an index of general neural inefficiency.
JOURNAL OF NEUROLOGY
(2021)
Article
Ophthalmology
Shuting Liu, Kangjian Xiang, Qiannan Lei, Suo Qiu, Mengqing Xiang, Kangxin Jin
Summary: Visual evoked potential (VEP) is commonly used to evaluate visual acuity. This study established a new invasive procedure for VEP recording in mice and compared VEP parameters recorded under different conditions. The results show that VEP is greatly influenced by electrode locations and the difference between day and night. The newly established VEP procedure is reliable and stable, and is particularly useful for detecting loss of retinal ganglion cells (RGCs) in mouse models.
EXPERIMENTAL EYE RESEARCH
(2022)
Article
Medicine, Research & Experimental
Lays Fernanda Nunes Dourado, Lucas Gomes Oliveira, Carolina Nunes da Silva, Cibele Rodrigues Toledo, Silvia Ligorio Fialho, Rodrigo Jorge, Armando Silva-Cunha Junior
Summary: The study demonstrates that ketamine is safe for intravitreal use up to a dose of 0.118 mmol.L-1. It shows particular efficiency in protecting the retina from ischemic injury, reducing cell death, and promoting recovery of retinal function within safe dosage range.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Ophthalmology
Merry Septemi Ekayanti, Corry Novita Mahama, Denny Jefferson Ngantung
Summary: The study aimed to obtain normative values of VEP latency and amplitude parameters in Indonesian adults and investigate their relationship with factors such as height, weight, BMI, head circumference, and visual acuity. Results showed that gender and age can affect P100 amplitude but not latency, while height, weight, BMI, head circumference, and visual acuity have no impact on P100 latency and amplitude.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Medicine, General & Internal
Gianluca Coppola, Cherubino Di Lorenzo, Davide Di Lenola, Mariano Serrao, Francesco Pierelli, Vincenzo Parisi
Summary: In patients with migraine, VEP recordings after photostress show dynamic changes and recovery depending on the migraine cycle. The percentage decrease in VEP amplitudes after photostress is lower in migraine patients compared to healthy volunteers, and is negatively correlated with the number of days since the last attack and positively correlated with attack frequency.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Clinical Neurology
Zachary T. Olmsted, Justin W. Silverstein, Evan H. Einstein, Jayne Sowulewski, Priscilla Nelson, John A. Boockvar, Randy S. D'Amico
Summary: Flash visual evoked potentials (fVEPs) provide a method to assess visual system functioning during tumor resection, but due to technical limitations, it has been underutilized in intraoperative neurophysiological monitoring. This review highlights the evolution of fVEPs as a monitoring technique and the importance of technological and intraoperative improvements.
NEUROSURGICAL REVIEW
(2023)
Article
Clinical Neurology
Ning Qiao, Xiaocui Yang, Chuzhong Li, Guofo Ma, Jie Kang, Chunhui Liu, Lei Cao, Yazhuo Zhang, Songbai Gui
Summary: Intraoperative VEP monitoring during EEES for craniopharyngioma can effectively predict postoperative visual changes in adult patients. Tight adhesion and larger tumor volume are strong predictors of postoperative visual impairment.
JOURNAL OF NEUROSURGERY
(2021)
Article
Clinical Neurology
Harshal A. Shah, Sabrina L. Begley, Prashin Unadkat, Kaitlin Kelly Hugo, Michael Schulder
Summary: Background: VEP recording is traditionally thought to be unreliable, but DC-VEPs may offer a solution by providing more accurate information. This study evaluated the obtainability and prognostic utility of DC-VEPs in predicting postoperative visual function deterioration in brain tumor patients.
JOURNAL OF CLINICAL NEUROSCIENCE
(2023)
Article
Construction & Building Technology
Songtao Hu, Mengyuan He, Guodan Liu, Mingli Lu, Ping Liang, Feng Liu
Summary: The study found that subjective feelings and pattern reversal visual evoked potential of personnel change with illuminance levels, reaching the lowest values at 700 lux. Fuzzy entropy analysis revealed a strong correlation between subjective voting and the visual nervous system. The research provides a method for evaluating the recommended illumination comfort zone.
BUILDING AND ENVIRONMENT
(2021)