A shift from N-glycolyl- to N-acetyl-sialic acid in the GM3 ganglioside impairs tumor development in mouse lymphocytic leukemia cells

NGcGM3/VSSP vaccine as treatment for melanoma patients

(2013) Kirenia Pérez et al.   Human Vaccines & Immunotherapeutics

Engineering the Binding Site of an Antibody against N-Glycolyl GM3: From Functional Mapping to Novel Anti-ganglioside Specificities

(2012) Gertrudis Rojas et al.   ACS Chemical Biology

Detection of N-glycolyated gangliosides in non-small-cell lung cancer using GMR8 monoclonal antibody

(2012) Nobuyoshi Hayashi et al.   CANCER SCIENCE

Glycans as targets for therapeutic antitumor antibodies

(2012) Catherine Rabu et al.   Future Oncology

Metabolism of Vertebrate Amino Sugars withN-Glycolyl Groups

(2012) Kalyan Banda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lonely killers

(2012) Yuniel Fernández-Marrero et al.   mAbs

N-Glycolyl GM3 ganglioside immunoexpression in oral mucosal melanomas of Chinese

(2012) Y Zhong et al.   ORAL DISEASES

Immune response to racotumomab in a child with relapsed neuroblastoma

(2012) C. Sampor et al.   Frontiers in Oncology

Preclinical evaluation of racotumomab, an anti-idiotype monoclonal antibody to N-glycolyl-containing gangliosides, with or without chemotherapy in a mouse model of non-small cell lung cancer

(2012) Valeria I. Segatori et al.   Frontiers in Oncology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Gangliosides and the multiscale modulation of membrane structure

(2011) Laura Cantù et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Detection of N-Glycolyl GM3 Ganglioside in Neuroectodermal Tumors by Immunohistochemistry: An Attractive Vaccine Target for Aggressive Pediatric Cancer

(2011) Alejandra M. Scursoni et al.   Clinical & Developmental Immunology

Immunology in the clinic review series; focus on cancer: glycolipids as targets for tumour immunotherapy

(2011) L. G. Durrant et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

A cytotoxic humanized anti-ganglioside antibody produced in a murine cell line defective of N-glycolylated-glycoconjugates

(2011) Yuniel Fernández-Marrero et al.   IMMUNOBIOLOGY

A Glycosphingolipid/Caveolin-1 Signaling Complex Inhibits Motility of Human Ovarian Carcinoma Cells

(2011) Alessandro Prinetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody

(2011) Yuniel Fernández-Marrero et al.   MOLECULAR IMMUNOLOGY

mMass3: A Cross-Platform Software Environment for Precise Analysis of Mass Spectrometric Data

(2010) Martin Strohalm et al.   ANALYTICAL CHEMISTRY

Heterophilic NeuGcGM3 ganglioside cancer vaccine in advanced melanoma patients: Results of a phase Ib/IIa study

(2010) Marta Osorio et al.   CANCER BIOLOGY & THERAPY

NGcGM3 Ganglioside: A Privileged Target for Cancer Vaccines

(2010) Luis E. Fernandez et al.   Clinical & Developmental Immunology

Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acidN-glycolylneuraminic acid

(2010) Rachel E. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipids and Membrane Lateral Organization

(2010) Sandro Sonnino et al.   Frontiers in Physiology

Tissue micro array analysis of ganglioside N-glycolyl GM3 expression and signal transducer and activator of transcription (STAT)-3 activation in relation to dendritic cell infiltration and microvessel density in non-small cell lung cancer

(2009) Hester van Cruijsen et al.   BMC CANCER

De-N-acetyl GM3 Promotes Melanoma Cell Migration and Invasion through Urokinase Plasminogen Activator Receptor Signaling-Dependent MMP-2 Activation

(2009) J.-W. Liu et al.   CANCER RESEARCH

Gangliosides in cell recognition and membrane protein regulation

(2009) Pablo HH Lopez et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Direct validation of NGcGM3 ganglioside as a new target for cancer immunotherapy

(2009) Mayrel Labrada et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Altered sphingolipid metabolism induced by tumor hypoxia - New vistas in glycolipid tumor markers

(2009) Jun Yin et al.   FEBS LETTERS

Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility

(2009) Sen-itiroh Hakomori   FEBS LETTERS

GM3 synthase overexpression results in reduced cell motility and in caveolin-1 upregulation in human ovarian carcinoma cells

(2009) A. Prinetti et al.   GLYCOBIOLOGY

The immunogenicity of L1210 lymphoma clones correlates with their ability to function as antigen-presenting cells

(2009) Kelly A. Cycon et al.   IMMUNOLOGY

Exogenous incorporation of neugc-rich mucin augments n-glycolyl sialic acid content and promotes malignant phenotype in mouse tumor cell lines

(2009) Mariano R Gabri et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Detection and Characterization of N-Glycolyated Gangliosides in Wilms Tumor by Immunohistochemistry

(2009) Alejandra M. Scursoni et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

Glycosphingolipid behaviour in complex membranes

(2008) Alessandro Prinetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 through the increase of ganglioside GM3

(2008) C Tringali et al.   CELL DEATH AND DIFFERENTIATION

Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: Potential implications for disease

(2008) V. Padler-Karavani et al.   GLYCOBIOLOGY

Multiple changes in sialic acid biology during human evolution

(2008) Ajit Varki   GLYCOCONJUGATE JOURNAL

Differential influence of the tumour-specific non-human sialic acid containing GM3 ganglioside on CD4+CD25- effector and naturally occurring CD4+CD25+ regulatory T cells function

(2008) J. de Leon et al.   INTERNATIONAL IMMUNOLOGY

Anti-ganglioside antibody-induced tumor cell death by loss of membrane integrity

(2008) L. Roque-Navarro et al.   MOLECULAR CANCER THERAPEUTICS

Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression

(2008) M. Hedlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA