Senescence-Induced Oxidative Stress Causes Endothelial Dysfunction

Adult-onset, short-term dietary restriction reduces cell senescence in mice

(2016) Chunfang Wang et al.   Aging-US

Disturbed Flow Promotes Endothelial Senescence via a p53-Dependent Pathway

(2014) Christina M. Warboys et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

In Vivo and In Vitro Analysis of Age-Associated Changes and Somatic Cellular Senescence in Renal Epithelial Cells

(2014) Birgit Berkenkamp et al.   PLoS One

Defining vascular aging and cardiovascular risk

(2012) Stéphane Laurent   JOURNAL OF HYPERTENSION

Cellular Senescence Limits Regenerative Capacity and Allograft Survival

(2012) H. Braun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

(2012) Marzia Fumagalli et al.   NATURE CELL BIOLOGY

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

(2012) Graeme Hewitt et al.   Nature Communications

Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging

(2011) Amy L. Sindler et al.   AGING CELL

Is cellular senescence important in pediatric kidney disease?

(2011) Christoph Jacobi et al.   PEDIATRIC NEPHROLOGY

Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress

(2010) Catarina Rippe et al.   AGING CELL

Expression of Chr9p21 genes CDKN2B (p15INK4b), CDKN2A (p16INK4a, p14ARF) and MTAP in human atherosclerotic plaque

(2010) Lesca Miriam Holdt et al.   ATHEROSCLEROSIS

Structural modifications in the arterial wall during physiological aging and as a result of diabetes mellitus in a mouse model: Are the changes comparable?

(2010) G. Prévost et al.   DIABETES & METABOLISM

Quantitative assessment of markers for cell senescence

(2010) Conor Lawless et al.   EXPERIMENTAL GERONTOLOGY

Ataxia Telangiectasia Mutated (ATM)-mediated DNA Damage Response in Oxidative Stress-induced Vascular Endothelial Cell Senescence

(2010) Hong Zhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Vascular Aging: New Perspectives

(2010) Z. Ungvari et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

Mitochondrial Telomerase Reverse Transcriptase Binds to and Protects Mitochondrial DNA and Function From Damage

(2009) Judith Haendeler et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Gender differences in age-related endothelial function in the murine aorta

(2009) Yasuhiro Takenouchi et al.   ATHEROSCLEROSIS

Telomere Shortening Reduces Regenerative Capacity after Acute Kidney Injury

(2009) J. H. Westhoff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Telomere biology in cardiovascular disease: the TERC-/- mouse as a model for heart failure and ageing

(2008) L. S.M. Wong et al.   CARDIOVASCULAR RESEARCH

Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction

(2008) Philip Wenzel et al.   CARDIOVASCULAR RESEARCH

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress

(2008) S. Ahmed et al.   JOURNAL OF CELL SCIENCE