Traumatic white matter injury and glial activation: From basic science to clinics

Delayed Increases in Microvascular Pathology after Experimental Traumatic Brain Injury Are Associated with Prolonged Inflammation, Blood–Brain Barrier Disruption, and Progressive White Matter Damage

(2014) Olena Y. Glushakova et al.   JOURNAL OF NEUROTRAUMA

Blast neurotrauma impairs working memory and disrupts prefrontal myo-inositol levels in rats

(2014) Venkata Siva Sai Sujith Sajja et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A Better Characterization of Spinal Cord Damage in Multiple Sclerosis: A Diffusional Kurtosis Imaging Study

(2013) E. Raz et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Delayed Complications From Exposure to Improvised Explosive Devices

(2013) Peter J. Cawley   ANNALS OF INTERNAL MEDICINE

Chronic neuropathological and neurobehavioral changes in a repetitive mild traumatic brain injury model

(2013) Benoit C. Mouzon et al.   ANNALS OF NEUROLOGY

Inflammation and white matter degeneration persist for years after a single traumatic brain injury

(2013) Victoria E. Johnson et al.   BRAIN

Moderate–severe traumatic brain injury causes delayed loss of white matter integrity: Evidence of fornix deterioration in the chronic stage of injury

(2013) Areeba Adnan et al.   BRAIN INJURY

White Matter Integrity Following Traumatic Brain Injury: The Association with Severity of Injury and Cognitive Functioning

(2013) Gershon Spitz et al.   BRAIN TOPOGRAPHY

Myelin loss and oligodendrocyte pathology in white matter tracts following traumatic brain injury in the rat

(2013) J. Flygt et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Rapid Accumulation of Endogenous Tau Oligomers in a Rat Model of Traumatic Brain Injury

(2013) Bridget E. Hawkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Corpus Callosum Integrity and Neuropsychological Performance After Traumatic Brain Injury

(2013) Patricia M. Arenth et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

Treatment with an anti-CD11d integrin antibody reduces neuroinflammation and improves outcome in a rat model of repeated concussion

(2013) Sandy R Shultz et al.   Journal of Neuroinflammation

The p38  MAPK Regulates Microglial Responsiveness to Diffuse Traumatic Brain Injury

(2013) A. D. Bachstetter et al.   JOURNAL OF NEUROSCIENCE

Effects of blast-induced neurotrauma on the nucleus accumbens

(2013) Venkata Siva Sai Sujith Sajja et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Inflammatory Consequences in a Rodent Model of Mild Traumatic Brain Injury

(2013) J. Regino Perez-Polo et al.   JOURNAL OF NEUROTRAUMA

Working Memory and Corpus Callosum Microstructural Integrity after Pediatric Traumatic Brain Injury: A Diffusion Tensor Tractography Study

(2013) Amery Treble et al.   JOURNAL OF NEUROTRAUMA

Non-Gaussian diffusion MRI assessment of brain microstructure in mild cognitive impairment and Alzheimer’s disease

(2013) Maria F. Falangola et al.   MAGNETIC RESONANCE IMAGING

Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation

(2013) Sophia Bardehle et al.   NATURE NEUROSCIENCE

Blast induces oxidative stress, inflammation, neuronal loss and subsequent short-term memory impairment in rats

(2013) H.J. Cho et al.   NEUROSCIENCE

Cingulum injury in patients with diffuse axonal injury: A diffusion tensor imaging study

(2013) Sung Ho Jang et al.   NEUROSCIENCE LETTERS

Characterizing Brain Structures and Remodeling after TBI Based on Information Content, Diffusion Entropy

(2013) Niloufar Fozouni et al.   PLoS One

Combining Biochemical and Imaging Markers to Improve Diagnosis and Characterization of Mild Traumatic Brain Injury in the Acute Setting: Results from a Pilot Study

(2013) Zhifeng Kou et al.   PLoS One

Amyloid-β Peptides and Tau Protein as Biomarkers in Cerebrospinal and Interstitial Fluid Following Traumatic Brain Injury: A Review of Experimental and Clinical Studies

(2013) Parmenion P. Tsitsopoulos et al.   Frontiers in Neurology

Cognitive Impairment in Mild Traumatic Brain Injury: A Longitudinal Diffusional Kurtosis and Perfusion Imaging Study

(2012) E.J. Grossman et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

White Matter Abnormalities in Veterans With Mild Traumatic Brain Injury

(2012) Ricardo E. Jorge et al.   AMERICAN JOURNAL OF PSYCHIATRY

Assessment of White Matter Injury and Outcome in Severe Brain Trauma

(2012) Damien Galanaud et al.   ANESTHESIOLOGY

Treatment of neurological injury with thymosin β4

(2012) Daniel C. Morris et al.   Annals of the New York Academy of Sciences

Computational Modeling of Axonal Microtubule Bundles under Tension

(2012) Stephen J. Peter et al.   BIOPHYSICAL JOURNAL

Atomic Force Microscopy Reveals Important Differences in Axonal Resistance to Injury

(2012) Margaret H. Magdesian et al.   BIOPHYSICAL JOURNAL

Robust detection of traumatic axonal injury in individual mild traumatic brain injury patients: Intersubject variation, change over time and bidirectional changes in anisotropy

(2012) Michael L. Lipton et al.   Brain Imaging and Behavior

Microglia activation along the corticospinal tract following traumatic brain injury in the rat: A neuroanatomical study

(2012) David M. Jacobowitz et al.   BRAIN RESEARCH

Mechanisms of calpain mediated proteolysis of voltage gated sodium channel α-subunits following in vitro dynamic stretch injury

(2012) Catherine R. von Reyn et al.   JOURNAL OF NEUROCHEMISTRY

Evaluation of age-related changes in translocator protein (TSPO) in human brain using 11C-[R]-PK11195 PET

(2012) Ajay Kumar et al.   Journal of Neuroinflammation

An in vitro injury model for SH-SY5Y neuroblastoma cells: Effect of strain and strain rate

(2012) Maciej Skotak et al.   JOURNAL OF NEUROSCIENCE METHODS

In Vitro Stretch Injury Induces Time- and Severity-Dependent Alterations of STEP Phosphorylation and Proteolysis in Neurons

(2012) Mahlet N. Mesfin et al.   JOURNAL OF NEUROTRAUMA

Blast-induced moderate neurotrauma (BINT) elicits early complement activation and tumor necrosis factor alpha (TNFα) release in a rat brain

(2012) Jurandir J. Dalle Lucca et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neuroinflammation and Synaptic Loss

(2012) Jagadeesh S. Rao et al.   NEUROCHEMICAL RESEARCH

Review: The long-term consequences of microglial activation following acute traumatic brain injury

(2012) C. Smith   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Altered gene expression in cultured microglia in response to simulated blast overpressure: Possible role of pulse duration

(2012) Michael J. Kane et al.   NEUROSCIENCE LETTERS

Diffusion tensor imaging detects axonal injury in a mouse model of repetitive closed-skull traumatic brain injury

(2012) Rachel E. Bennett et al.   NEUROSCIENCE LETTERS

Blast-induced neurotrauma leads to neurochemical changes and neuronal degeneration in the rat hippocampus

(2012) Venkata Siva Sai Sujith Sajja et al.   NMR IN BIOMEDICINE

Mild traumatic brain injury: a risk factor for neurodegeneration

(2012) Brandon E Gavett et al.   Alzheimers Research & Therapy

Assessment of the Effects of Acute and Repeated Exposure to Blast Overpressure in Rodents: Toward a Greater Understanding of Blast and the Potential Ramifications for Injury in Humans Exposed to Blast

(2012) Stephen Thomas Ahlers et al.   Frontiers in Neurology

Patient-Tailored Connectomics Visualization for the Assessment of White Matter Atrophy in Traumatic Brain Injury

(2012) Andrei Irimia et al.   Frontiers in Neurology

The usefulness of S100B, NSE, GFAP, NF-H, secretagogin and Hsp70 as a predictive biomarker of outcome in children with traumatic brain injury

(2011) Jiří Žurek et al.   ACTA NEUROCHIRURGICA

Mild Neurotrauma Indicates a Range-Specific Pressure Response to Low Level Shock Wave Exposure

(2011) Pamela J. VandeVord et al.   ANNALS OF BIOMEDICAL ENGINEERING

Inflammation after trauma: Microglial activation and traumatic brain injury

(2011) Anil F. Ramlackhansingh et al.   ANNALS OF NEUROLOGY

Targeting reactive astrogliosis by novel biotechnological strategies

(2011) Anna Maria Colangelo et al.   BIOTECHNOLOGY ADVANCES

Enhancing remyelination in disease--can we wrap it up?

(2011) M. R. Kotter et al.   BRAIN

The contribution of gliosis to diffusion tensor anisotropy and tractography following traumatic brain injury: validation in the rat using Fourier analysis of stained tissue sections

(2011) Matthew D. Budde et al.   BRAIN

Quantification of increased cellularity during inflammatory demyelination

(2011) Yong Wang et al.   BRAIN

Selective CDK Inhibitor Limits Neuroinflammation and Progressive Neurodegeneration after Brain Trauma

(2011) Shruti V Kabadi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Increased cerebral (R)-[11C]PK11195 uptake and glutamate release in a rat model of traumatic brain injury: a longitudinal pilot study

(2011) Hedy Folkersma et al.   Journal of Neuroinflammation

A Mouse Model of Blast Injury to Brain: Initial Pathological, Neuropathological, and Behavioral Characterization

(2011) Vassilis E. Koliatsos et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Repetitive Closed-Skull Traumatic Brain Injury in Mice Causes Persistent Multifocal Axonal Injury and Microglial Reactivity

(2011) Yoshitsugu Shitaka et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mild Stretch-Induced Injury Increases Susceptibility to Interleukin-1β-Induced Release of Matrix Metalloproteinase-9 from Astrocytes

(2011) Hantamalala Ralay Ranaivo et al.   JOURNAL OF NEUROTRAUMA

Thalamus and Cognitive Impairment in Mild Traumatic Brain Injury: A Diffusional Kurtosis Imaging Study

(2011) Elan J. Grossman et al.   JOURNAL OF NEUROTRAUMA

Widespread and Prolonged Increase in (R)-11C-PK11195 Binding After Traumatic Brain Injury

(2011) H. Folkersma et al.   JOURNAL OF NUCLEAR MEDICINE

Subject-specific changes in brain white matter on diffusion tensor imaging after sports-related concussion

(2011) Jeffrey J. Bazarian et al.   MAGNETIC RESONANCE IMAGING

Association of CSF Biomarkers and Secondary Insults Following Severe Traumatic Brain Injury

(2011) Deborah M. Stein et al.   Neurocritical Care

Diffusion kurtosis as an in vivo imaging marker for reactive astrogliosis in traumatic brain injury

(2011) Jiachen Zhuo et al.   NEUROIMAGE

Longitudinal changes of structural connectivity in traumatic axonal injury

(2011) J. Y. Wang et al.   NEUROLOGY

Oligodendrocyte vulnerability following traumatic brain injury in rats

(2011) George Lotocki et al.   NEUROSCIENCE LETTERS

MRI evaluation of axonal reorganization after bone marrow stromal cell treatment of traumatic brain injury

(2011) Quan Jiang et al.   NMR IN BIOMEDICINE

Relationship of Serum and Cerebrospinal Fluid Biomarkers With Intracranial Hypertension and Cerebral Hypoperfusion After Severe Traumatic Brain Injury

(2011) Deborah M. Stein et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Secondary insults following traumatic brain injury enhance complement activation in the human brain and release of the tissue damage marker S100B

(2010) Bo-Michael Bellander et al.   ACTA NEUROCHIRURGICA

In vitrocomparison of sputtered iridium oxide and platinum-coated neural implantable microelectrode arrays

(2010) S Negi et al.   Biomedical Materials

Ubiquitin C-terminal hydrolase-L1 as a biomarker for ischemic and traumatic brain injury in rats

(2010) Ming C. Liu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Diffusion tensor imaging and white matter lesions at the subacute stage in mild traumatic brain injury with persistent neurobehavioral impairment

(2010) Arnaud Messé et al.   HUMAN BRAIN MAPPING

Diffusion Tensor Imaging of Mild Traumatic Brain Injury

(2010) Sumit N. Niogi et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

The Role of Advanced MR Imaging Findings as Biomarkers of Traumatic Brain Injury

(2010) Zhifeng Kou et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury

(2010) Charu Venkatesan et al.   Journal of Neuroinflammation

Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury

(2010) Ryan D. Readnower et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Treatment of traumatic brain injury with thymosin β4 in rats

(2010) Ye Xiong et al.   JOURNAL OF NEUROSURGERY

The fabrication of low-impedance nanoporous gold multiple-electrode arrays for neural electrophysiology studies

(2010) Erkin Seker et al.   NANOTECHNOLOGY

GFAP and S100B are biomarkers of traumatic brain injury: An observational cohort study

(2010) P. E. Vos et al.   NEUROLOGY

A prospective diffusion tensor imaging study in mild traumatic brain injury

(2010) A. R. Mayer et al.   NEUROLOGY

Increased diffusivity in acute multiple sclerosis lesions predicts risk of black hole

(2010) R. T. Naismith et al.   NEUROLOGY

Thymosin β4 improves functional neurological outcome in a rat model of embolic stroke

(2010) D.C. Morris et al.   NEUROSCIENCE

MRI quantification of non-Gaussian water diffusion by kurtosis analysis

(2010) Jens H. Jensen et al.   NMR IN BIOMEDICINE

Preliminary observations of increased diffusional kurtosis in human brain following recent cerebral infarction

(2010) Jens H. Jensen et al.   NMR IN BIOMEDICINE

Erythropoietin Amplifies Stroke-Induced Oligodendrogenesis in the Rat

(2010) Li Zhang et al.   PLoS One

Cerebral Gliomas: Diffusional Kurtosis Imaging Analysis of Microstructural Differences

(2010) Peter Raab et al.   RADIOLOGY

Letter from the Guest Editor

(2010) Frank W. Pfrieger   Cell Adhesion & Migration

Morphologic and Biochemical Characterization of Brain Injury in a Model of Controlled Blast Overpressure Exposure

(2010) Stanislav I. Svetlov et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Voxel-Based Analysis of Diffusion Tensor Imaging in Mild Traumatic Brain Injury in Adolescents

(2009) Z. Chu et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Astrocytes in the damaged brain: Molecular and cellular insights into their reactive response and healing potential

(2009) Annalisa Buffo et al.   BIOCHEMICAL PHARMACOLOGY

Sensorimotor cortex aspiration: A model for studying Wallerian degeneration-induced glial reactivity along the entire length of a single CNS axonal pathway

(2009) Mohsen Basiri et al.   BRAIN RESEARCH BULLETIN

Role of glial cells in the formation and maintenance of synapses

(2009) Frank W. Pfrieger   BRAIN RESEARCH REVIEWS

Calcium dyshomeostasis in white matter pathology

(2009) Carlos Matute   CELL CALCIUM

Roles of glial cells in synapse development

(2009) Frank W. Pfrieger   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration

(2009) Min D. Tang-Schomer et al.   FASEB JOURNAL

Bone Marrow Stromal Cells Increase Oligodendrogenesis after Stroke

(2009) Jing Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Disruption of the Ubiquitin Proteasome System following Axonal Stretch Injury Accelerates Progression to Secondary Axotomy

(2009) Jerome A. Staal et al.   JOURNAL OF NEUROTRAUMA

A Critical Problem Begging for New Insight and New Therapies

(2009) Patrick M. Kochanek et al.   JOURNAL OF NEUROTRAUMA

A Panel of Neuron-Enriched Proteins as Markers for Traumatic Brain Injury in Humans

(2009) Robert Siman et al.   JOURNAL OF NEUROTRAUMA

In Situ Detection of Inflammatory Mediators in Post Mortem Human Brain Tissue after Traumatic Injury

(2009) Tony Frugier et al.   JOURNAL OF NEUROTRAUMA

Evaluating the Relationship between Memory Functioning and Cingulum Bundles in Acute Mild Traumatic Brain Injury Using Diffusion Tensor Imaging

(2009) Trevor C. Wu et al.   JOURNAL OF NEUROTRAUMA

Astrocytes going live: advances and challenges

(2009) Axel Nimmerjahn   JOURNAL OF PHYSIOLOGY-LONDON

Symptom complaints following combat-related traumatic brain injury: Relationship to traumatic brain injury severity and posttraumatic stress disorder

(2009) HEATHER G. BELANGER et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Cognitive sequelae of blast-related versus other mechanisms of brain trauma

(2009) HEATHER G. BELANGER et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

About “axial” and “radial” diffusivities

(2009) Claudia A.M. Wheeler-Kingshott et al.   MAGNETIC RESONANCE IN MEDICINE

Free water elimination and mapping from diffusion MRI

(2009) Ofer Pasternak et al.   MAGNETIC RESONANCE IN MEDICINE

Neurological functional recovery after thymosin beta4 treatment in mice with experimental auto encephalomyelitis

(2009) J. Zhang et al.   NEUROSCIENCE

Stretch growth of integrated axon tracts: Extremes and exploitations

(2009) Douglas H. Smith   PROGRESS IN NEUROBIOLOGY

Diffusion-Tensor Imaging Implicates Prefrontal Axonal Injury in Executive Function Impairment Following Very Mild Traumatic Brain Injury

(2009) Michael L. Lipton et al.   RADIOLOGY

Diffusion Tensor Imaging Characteristics of the Corpus Callosum in Mild, Moderate, and Severe Traumatic Brain Injury

(2008) D.R. Rutgers et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Extent of Microstructural White Matter Injury in Postconcussive Syndrome Correlates with Impaired Cognitive Reaction Time: A 3T Diffusion Tensor Imaging Study of Mild Traumatic Brain Injury

(2008) S.N. Niogi et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Structural dissociation of attentional control and memory in adults with and without mild traumatic brain injury

(2008) S. N. Niogi et al.   BRAIN

Short-term DTI predictors of cognitive dysfunction in mild traumatic brain injury

(2008) Laura Miles et al.   BRAIN INJURY

Mechanically-induced membrane poration causes axonal beading and localized cytoskeletal damage

(2008) Devrim Kilinc et al.   EXPERIMENTAL NEUROLOGY

Diffusion Tensor Imaging in Relation to Cognitive and Functional Outcome of Traumatic Brain Injury in Children

(2008) Harvey S. Levin et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

Age-related non-Gaussian diffusion patterns in the prefrontal brain

(2008) Maria F. Falangola et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

The life, death, and replacement of oligodendrocytes in the adult CNS

(2008) Dana M. McTigue et al.   JOURNAL OF NEUROCHEMISTRY

The Phosphorylated Axonal Form of the Neurofilament Subunit NF-H (pNF-H) as a Blood Biomarker of Traumatic Brain Injury

(2008) Kevin J. Anderson et al.   JOURNAL OF NEUROTRAUMA

Classification of Traumatic Brain Injury for Targeted Therapies

(2008) Kathryn E. Saatman et al.   JOURNAL OF NEUROTRAUMA

Diffusion tensor imaging of acute mild traumatic brain injury in adolescents

(2008) E. A. Wilde et al.   NEUROLOGY

Up-regulation of reactivity and survival genes in astrocytes after exposure to short duration overpressure

(2008) Pamela J. VandeVord et al.   NEUROSCIENCE LETTERS

Cell–cell interaction modulates neuroectodermal specification of embryonic stem cells

(2008) Biju Parekkadan et al.   NEUROSCIENCE LETTERS

Mild Traumatic Brain Injury in U.S. Soldiers Returning from Iraq

(2008) Charles W. Hoge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of extracellular factors in axon regeneration in the CNS: implications for therapy

(2008) Noreen M Gervasi et al.   Regenerative Medicine

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

(2007) Michael T. Fitch et al.   EXPERIMENTAL NEUROLOGY