The PTEN inhibitor bisperoxovanadium enhances myelination by amplifying IGF-1 signaling in rat and human oligodendrocyte progenitors

PTEN Inhibition to Facilitate Intrinsic Regenerative Outgrowth of Adult Peripheral Axons

(2013) K. J. Christie et al.   JOURNAL OF NEUROSCIENCE

Alterations in tyrosine kinase receptor (Trk) expression induced by insulin-like growth factor-1 in cultured dorsal root ganglion neurons

(2012) Hao Li et al.   BRAIN RESEARCH BULLETIN

Delayed administration of a PTEN inhibitor BPV improves functional recovery after experimental stroke

(2012) L. Mao et al.   NEUROSCIENCE

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology

Regulation of remyelination in multiple sclerosis

(2011) Khalid A. Hanafy et al.   FEBS LETTERS

GSK3β negatively regulates oligodendrocyte differentiation and myelination in vivo

(2011) Kasum Azim et al.   GLIA

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

(2011) Fang Sun et al.   NATURE

Human Fetal Oligodendrocyte Progenitor Cells from Different Gestational Stages Exhibit Substantially Different Potential to Myelinate

(2011) Qiao-Ling Cui et al.   STEM CELLS AND DEVELOPMENT

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

(2010) Emily P. Harrington et al.   ANNALS OF NEUROLOGY

PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway

(2010) G.D. Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

β-catenin mediates insulin-like growth factor-I actions to promote cyclin D1 mRNA expression, cell proliferation and survival in oligodendroglial cultures

(2010) Ping Ye et al.   GLIA

Response of Human Oligodendrocyte Progenitors to Growth Factors and Axon Signals

(2010) Qiao Ling Cui et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Elevated Phosphatidylinositol 3,4,5-Trisphosphate in Glia Triggers Cell-Autonomous Membrane Wrapping and Myelination

(2010) S. Goebbels et al.   JOURNAL OF NEUROSCIENCE

Crosstalk Between the PI3K/mTOR and MEK/ERK Pathways Involved in the Maintenance of Self-Renewal and Tumorigenicity of Glioblastoma Stem-Like Cells

(2010) Jun Sunayama et al.   STEM CELLS

Insulin-like growth factor-I receptor signal transduction and the Janus Kinase/Signal Transducer and Activator of Transcription (JAK-STAT) pathway

(2009) Eddy Himpe et al.   BIOFACTORS

IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways

(2009) Olivia Bibollet-Bahena et al.   JOURNAL OF NEUROCHEMISTRY

Phosphatidylinositol 4,5-Bisphosphate-Dependent Interaction of Myelin Basic Protein with the Plasma Membrane in Oligodendroglial Cells and Its Rapid Perturbation by Elevated Calcium

(2009) S. Nawaz et al.   JOURNAL OF NEUROSCIENCE

Activation of the Mammalian Target of Rapamycin (mTOR) Is Essential for Oligodendrocyte Differentiation

(2009) W. A. Tyler et al.   JOURNAL OF NEUROSCIENCE

Myelin Basic Protein as a “PI(4,5)P2-Modulin”: A New Biological Function for a Major Central Nervous System Protein†

(2008) Abdiwahab A. Musse et al.   BIOCHEMISTRY

Constitutively Active Akt Induces Enhanced Myelination in the CNS

(2008) A. I. Flores et al.   JOURNAL OF NEUROSCIENCE

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE