Genetic modeling of gliomas in mice: New tools to tackle old problems

Neurofibromin 1 (NF1) Defects Are Common in Human Ovarian Serous Carcinomas and Co-occur with TP53 Mutations

(2015) Navneet Sangha et al.   NEOPLASIA

Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and Radioresistance

(2015) Kimmo J. Hatanpaa et al.   NEOPLASIA

Modeling Adult Gliomas Using RCAS/t-va Technology

(2014) Dolores Hambardzumyan et al.   Translational Oncology

A reproducible brain tumour model established from human glioblastoma biopsies

(2010) Jian Wang et al.   BMC CANCER

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Preclinical Evaluation of Radiation and Perifosine in a Genetically and Histologically Accurate Model of Brainstem Glioma

(2010) O. J. Becher et al.   CANCER RESEARCH

Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells

(2010) Nikki Charles et al.   Cell Stem Cell

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

(2010) M.-d.-M. Inda et al.   GENES & DEVELOPMENT

EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism

(2010) G Pines et al.   ONCOGENE

Recent Insights into PDGF-Induced Gliomagenesis

(2009) Filippo Calzolari et al.   BRAIN PATHOLOGY

Expression of Mutant p53 Proteins Implicates a Lineage Relationship between Neural Stem Cells and Malignant Astrocytic Glioma in a Murine Model

(2009) Yuan Wang et al.   CANCER CELL

Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model

(2009) Sheila Alcantara Llaguno et al.   CANCER CELL

PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells

(2009) Anne-Marie Bleau et al.   Cell Stem Cell

Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer

(2009) Tetsuya Mitsudomi et al.   FEBS Journal

Inducible site-specific recombination in neural stem/progenitor cells

(2009) Jian Chen et al.   GENESIS

GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in aTrp53 nullbackground

(2009) Sanna-Maria Hede et al.   GLIA

Sonic Hedgehog Pathway Activation Is Induced by Acute Brain Injury and Regulated by Injury-Related Inflammation

(2009) N. M. Amankulor et al.   JOURNAL OF NEUROSCIENCE

Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma

(2009) N Lindberg et al.   ONCOGENE

Glioblastoma Subclasses Can Be Defined by Activity among Signal Transduction Pathways and Associated Genomic Alterations

(2009) Cameron Brennan et al.   PLoS One

Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis

(2009) Haihao Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic EGFR Signaling Networks in Glioma

(2009) P. H. Huang et al.   Science Signaling

Spinal Glioma: Platelet-Derived Growth Factor B-Mediated Oncogenesis in the Spinal Cord

(2008) Y. Hitoshi et al.   CANCER RESEARCH

Cancer Stem Cells Are Enriched in the Side Population Cells in a Mouse Model of Glioma

(2008) M. A. Harris et al.   CANCER RESEARCH

Pten Haploinsufficiency Accelerates Formation of High-Grade Astrocytomas

(2008) C.-H. Kwon et al.   CANCER RESEARCH

A Specialized Vascular Niche for Adult Neural Stem Cells

(2008) Masoud Tavazoie et al.   Cell Stem Cell

Adult SVZ Stem Cells Lie in a Vascular Niche: A Quantitative Analysis of Niche Cell-Cell Interactions

(2008) Qin Shen et al.   Cell Stem Cell

EGFR family: Structure physiology signalling and therapeutic targets†

(2008) Antony W. Burgess   GROWTH FACTORS

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Initiation of Oligodendrocyte Progenitor Cell Migration by a PDGF-A Activated Extracellular Regulated Kinase (ERK) Signaling Pathway

(2008) Emma E. Frost et al.   NEUROCHEMICAL RESEARCH

Expanding the role of surgery in intractable extratemporal pediatric epilepsy

(2008) Monisha Goyal et al.   Neurosurgical Focus

Glioma Formation, Cancer Stem Cells, and Akt Signaling

(2008) Dolores Hambardzumyan et al.   Stem Cell Reviews and Reports