Article
Geriatrics & Gerontology
Junning Fan, Canqing Yu, Yuanjie Pang, Yu Guo, Pei Pei, Zhijia Sun, Ling Yang, Yiping Chen, Huaidong Du, Dianjianyi Sun, Yanjie Li, Junshi Chen, Robert Clarke, Zhengming Chen, Jun Lv, Liming Li
Summary: This study found that adherence to a healthy lifestyle in middle-aged and older Chinese adults may help slow the rate of biological aging, reducing the risk of worsening frailty status.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Geriatrics & Gerontology
Robert Middleton, Jose Luis Poveda, Francesc Orfila Pernas, Daniel Martinez Laguna, Adolfo Diez Perez, Xavier Nogues, Cristina Carbonell Abella, Carlen Reyes, Daniel Prieto-Alhambra
Summary: The study analyzed 893,211 subjects aged 75 and older, classified into fit, mild, moderate, and severely frail categories. The results showed that frail subjects had significantly increased risks of falls, all-cause mortality, and fractures, with severely frail individuals at the highest risk.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Geriatrics & Gerontology
Erwin Stolz, Emiel O. Hoogendijk, Hannes Mayerl, Wolfgang Freidl
Summary: Various studies have shown consistent associations between current FI levels, baseline FI levels, and mortality. Additionally, individuals with steeper FI growth have a higher risk of mortality.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Geriatrics & Gerontology
Mario Ulises Perez-Zepeda, Judith Godin, Joshua J. Armstrong, Melissa K. Andrew, Arnold Mitnitski, Susan Kirkland, Kenneth Rockwood, Olga Theou
Summary: Frailty is becoming a growing concern in Canada, especially as the population ages. By using a standardized frailty index, levels of frailty among Canadians aged 45 and above can be accurately measured and compared. This information can provide valuable insights for clinicians, researchers, stakeholders, and the general public in understanding frailty and its implications, particularly in relation to age and gender.
Article
Geriatrics & Gerontology
Benjamin Landre, Celine Ben Hassen, Mika Kivimaki, Mikaela Bloomberg, Aline Dugravot, Alexis Schniztler, Severine Sabia, Archana Singh-Manoux
Summary: This study examined changes in physical and mental functioning before the onset of frailty using repeat data spanning 25 years. The results showed that differences in trajectories of physical and mental functioning were observable 25 years before the onset of frailty. Furthermore, lower physical and mental functioning scores at age 50 were associated with an increased risk of developing frailty at older ages.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Geriatrics & Gerontology
Xingqi Cao, Chen Chen, Jingyun Zhang, Qian-Li Xue, Emiel O. Hoogendijk, Xiaoting Liu, Shujuan Li, Xiaofeng Wang, Yimin Zhu, Zuyun Liu
Summary: This study determined the proportions of vulnerable individuals identified by three aging metrics that incorporate cognitive and physical function, and investigated their associations with mortality risk. The results showed that all three metrics were able to predict mortality risk, with CI-PF and FI performing better than age and sex alone. The findings highlight the importance of incorporating cognitive and physical function in risk stratification.
Article
Critical Care Medicine
Jai N. Darvall, Rinaldo Bellomo, Eldho Paul, Michael Bailey, Paul J. Young, Alice Reid, Kenneth Rockwood, David Pilcher
Summary: The study showed that population-scale frailty screening using CFS in ICUs in Australia and New Zealand can effectively identify high-risk patients, with greater frailty associated with poorer outcomes. Frailty remains highly predictive of mortality, even among patients younger than 50 years.
Article
Medicine, General & Internal
Maria C. Inacio, Robert N. Jorissen, Steve Wesselingh, Janet K. Sluggett, Craig Whitehead, John Maddison, John Forward, Alice Bourke, Gillian Harvey, Maria Crotty
Summary: In this study involving individuals entering residential aged care facilities, it was found that 18.0% experienced unplanned hospitalisations within 90 days of entry, while 22.6% required emergency department presentations. Various predictors, including modifiable factors, were identified to influence these outcomes.
Article
Critical Care Medicine
Kamil Polok, Jakub Fronczek, Antonio Artigas, Hans Flaatten, Bertrand Guidet, Dylan W. De Lange, Jesper Fjolner, Susannah Leaver, Michael Beil, Sigal Sviri, Raphael Romano Bruno, Bernhard Wernly, Bernardo Bollen Pinto, Joerg C. Schefold, Dorota Studzinska, Michael Joannidis, Sandra Oeyen, Brian Marsh, Finn H. Andersen, Rui Moreno, Maurizio Cecconi, Christian Jung, Wojciech Szczeklik
Summary: This study evaluated the use of noninvasive ventilation (NIV) in Europe and identified factors associated with outcomes of COVID-19 patients treated with NIV. The frequency of NIV use varied across European countries, and higher severity of illness and frailty were associated with increased risk of NIV failure. Primary invasive mechanical ventilation (IMV) was associated with better outcomes compared to primary NIV.
Article
Public, Environmental & Occupational Health
Daniela Anker, Cristian Carmeli, Marcel Zwahlen, Nicolas Rodondi, Valerie Santschi, Yves Henchoz, Christina Wolfson, Arnaud Chiolero
Summary: A study found that there is no strong relationship between blood pressure and transitions in frailty states among older adults. This suggests that there is no well-defined optimal blood pressure level to prevent frailty in this population.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Medicine, General & Internal
Alyssa Chan-Cuzydlo, Dustin J. Harrison, Brian L. Pike, Bart J. Currie, Mark Mayo, Mark G. Salvador, William R. Hulsey, Joseph Azzarello, Jeffrey Ellis, Daniel Kim, William King-Lewis, Jessica Nicole Smith, Barbara Rodriguez, Ryan C. Maves, James Lawler, Kevin L. Schully
Summary: The study describes a cohort of US Marines and Sailors who participated in joint training exercises in Australia between 2016-2020. The participants were predominantly white males under 24 years old, with most being junior enlisted and non-commissioned officers, particularly from infantry occupational specialties. Future plans include screening for various infectious diseases endemic in Australia and characterizing immune responses in the participants.
Article
Geriatrics & Gerontology
Dina Moxness Konglevoll, Lene Frost Andersen, Laila Arnesdatter Hopstock, Bjorn Heine Strand, Magne Thoresen, Torunn Holm Totland, Anette Hjartaker, Monica Hauger Carlsen
Summary: This study examined the association between long-term habitual fish intake and pre-frailty in older adults in Norway. The results showed that a higher frequency of lean, fatty, and total fish intake was associated with a lower risk of pre-frailty. Additionally, a pattern of consistent frequent fish intake over time was also related to a lower risk of pre-frailty.
Article
Geriatrics & Gerontology
Daniel Eduardo da Cunha Leme, Cesar de Oliveira
Summary: Machine learning models can be used to predict future frailty in the community setting. However, outcome variables for epidemiologic data sets such as frailty usually have an imbalance between categories, adversely affecting the performance of ML models. The study found that balancing the data set and using random forest (RF) improved the performance of predicting frailty.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Gerontology
Tessa Clemens, Amy E. Peden, Richard C. Franklin
Summary: The study reveals that unintentional fatal drowning rates among older adults aged 65 years and older vary in Australia, Canada, and New Zealand, and are increasing with the aging population. Different countries and age bands have significant locations and activities associated with older adult drowning.
JOURNAL OF AGING AND HEALTH
(2021)
Article
Transplantation
Benjamin M. Anderson, Muhammad Qasim, Gonzalo Correa, Felicity Evison, Suzy Gallier, Charles J. Ferro, Thomas A. Jackson, Adnan Sharif
Summary: Frailty among haemodialysis patients is associated with hospitalization and mortality, but further discrimination of risk is needed due to the high prevalence of frailty. This study found that incorporating self-reported health with frailty measurement can help identify the most at-risk frail individuals.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Geriatrics & Gerontology
Renuka Visvanathan, Damith C. Ranasinghe, Kylie Lange, Anne Wilson, Joanne Dollard, Eileen Boyle, Katherine Jones, Michael Chesser, Katharine Ingram, Stephen Hoskins, Clarabelle Pham, Jonathan Karnon, Keith D. Hill
Summary: The Ambient Intelligent Geriatric Management (AmbIGeM) system did not significantly reduce the rate of falls, rate of injurious falls, or proportion of falters among older patients in the trial. However, a post hoc analysis showed a decrease in falls and injurious falls rate in the Geriatric Evaluation and Management Unit wards. Further exploration and refinement of the technology is warranted based on these findings.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Food Science & Technology
Anupam Datta Gupta, Suzanne Edwards, Jessica Smith, John Snow, Renuka Visvanathan, Graeme Tucker, David Wilson
Summary: This study conducted a systematic review and meta-analysis on the use of Botulinum toxin A (BoNT-A) in the treatment of neuropathic pain (NP). The meta-analysis results showed that BoNT-A is effective in reducing pain in NP patients. However, the evidence from small-scale randomized controlled trials (RCTs) is limited. Further research is needed to establish BoNT-A as a first-line treatment option.
Article
Environmental Sciences
Alana Hansen, Terence Williamson, Dino Pisaniello, Helen Bennetts, Joost van Hoof, Larissa Arakawa Martins, Renuka Visvanathan, Jian Zuo, Veronica Soebarto
Summary: Despite staying mostly indoors, older people are more susceptible to health issues related to extreme hot and cold weather. A study focused on the thermal environment of housing for older Australians and found that indoor temperatures could reach above 35 degrees C. The research highlights the impact of temperature on the wellbeing of older people and provides guidelines for maintaining home environments conducive to their health.
Article
Nutrition & Dietetics
Allie S. Carew, Rania A. Mekary, Susan Kirkland, Olga Theou, Ferhan Siddiqi, Robin Urquhart, Michelle George, Chris Blanchard, Mary L. Biggs, Luc Djousse, Kenneth J. Mukamal, Leah E. Cahill
Summary: This study aimed to assess the relationship between breakfast frequency and timing and T2DM risk in older adults and found that a later daily first eating occasion time was associated with a lower risk of T2DM, particularly in participants with impaired fasting glucose at baseline.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Review
Health Care Sciences & Services
Alexandra Mudd, Rebecca Feo, Maria Pinero A. de Plaza, Matthew Tieu, Shila Y. Paia, Jenny Cleland, Alice Windle, Stacey George, Mark Q. Thompson, Rachel C. Ambagtsheer, Amanda Muller, Anna Hall, Belinda Lange
Summary: This scoping review investigates the use of digital technology in the inpatient setting to promote communication in the early stages of an infectious disease outbreak. The results demonstrate the diverse use of digital technology during the early stages of the COVID-19 pandemic in the inpatient setting. However, there is limited data and guidance to support clinicians in using digital technology to establish therapeutic relationships.
TELEMEDICINE AND E-HEALTH
(2023)
Article
Cardiac & Cardiovascular Systems
Jack Quach, Dustin Scott Kehler, Nicholas Giacomantonio, Caitlin McArthur, Chris Blanchard, Wanda Firth, Kenneth Rockwood, Olga Theou
Summary: This study aims to examine the relationship between admission frailty and frailty changes during cardiac rehabilitation with 5-year outcomes. The results show that admission frailty is associated with time to mortality, first hospitalization, first emergency department visit, and the number of hospitalizations, hospital days, and ED visits. Improvements in frailty during cardiac rehabilitation are associated with delayed all-cause hospitalization.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Geriatrics & Gerontology
Joanne Dollard, Jane Edwards, Lalit Yadav, Virginie Gaget, David Tivey, Maria C. C. Inacio, Guy J. J. Maddern, Renuka Visvanathan
Summary: This study investigates the economic and cost considerations of mobile X-ray services (MXS) in residential aged care facilities (RACFs) according to stakeholders, residents, and informal carers (ICs). It was found that private providers charge residents an additional fee for business viability, which may serve as a barrier for some residents to access MXS.
AUSTRALASIAN JOURNAL ON AGEING
(2023)
Article
Geriatrics & Gerontology
R. Visvanathan, K. Lange, J. Selvam, J. Dollard, E. Boyle, K. Jones, K. Ingram, P. Shibu, A. Wilson, D. C. Ranasinghe, J. Karnon, K. D. Hill
Summary: This study compares characteristics of patients who fall with those who did not fall and characterizes falls through three reporting methods. The results show that patients who fall are more likely to have cognitive impairment, be admitted with falls, and have poor health outcomes. The majority of falls are captured from medical records, while clinician and incident reports have some omissions. The study emphasizes the need to improve fall reporting methods and use multiple approaches to identify falls.
AUSTRALASIAN JOURNAL ON AGEING
(2023)
Article
Geriatrics & Gerontology
Laura C. Edney, Hossein Haji Ali Afzali, Renuka Visvanathan, Barbara Toson, Jonathan Karnon
Summary: This study examines the impact of delayed home care package access on healthcare costs for older adults. The results suggest that healthcare costs increase after receiving a home care package, particularly in terms of inpatient care.
GERIATRICS & GERONTOLOGY INTERNATIONAL
(2023)
Article
Geriatrics & Gerontology
Benjamin T. Schumacher, Dustin S. Kehler, Alexander M. Kulminski, Yujia (Susanna) Qiao, Stacy L. Andersen, Theresa Gmelin, Kaare Christensen, Mary K. Wojczynski, Olga Theou, Kenneth Rockwood, Anne B. Newman, Nancy W. Glynn
Summary: The study examines the association between frailty and perceived physical and mental fatigability. The findings suggest that higher levels of frailty are associated with greater severity of physical and mental fatigue.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Geriatrics & Gerontology
Erwin Stolz, Hannes Mayerl, Judith Godin, Emiel O. Hoogendijk, Olga Theou, Wolfgang Freidl, Kenneth Rockwood
Summary: This study examined the reliability of the Frailty Index (FI) and found that it demonstrated good internal consistency and reliability in differentiating frailty levels among community-dwelling older adults. However, measurement error was large, suggesting that small changes in FI may not reliably detect individual health deteriorations or improvements.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Shin J. Liau, Shota Hamada, Agathe D. Jadczak, Nobuo Sakata, Samanta Lalic, Rumiko Tsuchiya-Ito, Reina Taguchi, Renuka Visvanathan, J. Simon Bell
Summary: This study investigated the use of symptomatic and preventive medications according to age and frailty in Australian and Japanese nursing homes. The results showed that in Australia, the ratio of symptomatic to preventive medications was higher with increasing frailty but lower with age. In Japan, there was no significant difference in the mean number of symptomatic and preventive medications irrespective of age and frailty.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Primary Health Care
Sally S. Ahip, Sazlina S. Ghazali, Olga Theou, Azah A. Samad, Sabrina Lukas, Ummu K. Mustapha, Mark Q. Thompson, Renuka Visvanathan
Summary: This study confirms the reliability and convergent validity of the PFFS-M among patients, caregivers, and health care professionals of different educational levels. Additionally, cutoffs for frailty severity were developed for the use of this tool in primary care clinics.
