Review
Psychology, Multidisciplinary
Alison Warren
Summary: Dementia has become a major global health crisis, with behavioral and psychological symptoms being prominent clinical features. These symptoms are often attempts by dementia patients to communicate unmet needs. Understanding and meeting these needs is crucial for providing quality care.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Nutrition & Dietetics
Eiichi Katsumoto, Toru Ishida, Kenji Kinoshita, Miho Shimizu, Toshihito Tsutsumi, Yoko Nagai, Masakazu Nishimura, Toshio Yokouchi, Yasushi Yoshida
Summary: This study aimed to investigate the effects of Yokukansankachimpihange on behavioral and psychological symptoms of dementia. The results showed a significant improvement in Behave-AD score after 8 weeks, but there were no significant changes in MMSE, N-ADL, and gastrointestinal symptoms during the treatment period.
FRONTIERS IN NUTRITION
(2021)
Review
Geriatrics & Gerontology
Ying-Ling Jao, Julian Wang, Yo-Jen Liao, Jyotsana Parajuli, Diane Berish, Marie Boltz, Kimberly van Haitsma, Nan Wang, Lauren McNally, Margaret Calkins
Summary: This review synthesized research evidence on the effect of ambient bright light (BL) on behavioral and psychological symptoms of dementia (BPSD). The findings suggest that ambient BL has a positive effect on depressive symptoms and agitation in persons with dementia, but the evidence on other BPSD is mixed or limited. Further research is needed to explore the effect of ambient BL on BPSD with attention to lighting parameters, measurement approaches, and intervention fidelity.
INNOVATION IN AGING
(2022)
Article
Clinical Neurology
Solaphat Hemrungrojn, Sookjaroen Tangwongchai, Thammanard Charernboon, Muthita Phanasathit, Pisit Chaipresertsud, Pacharaporn Maleevach, Yuttachai Likitjaroen, Kammant Phanthumchinda, Ratiya Assawatinna, Arisara Amrapala, Michael Maes
Summary: The purpose of this study was to validate the Thai version of the Neuropsychiatric Inventory Questionnaire (NPI-Q) as a screening tool for behavioral and psychological symptoms of dementia (BPSD) and examine the relationship between cognitive performance and BPSD in elderly individuals with amnestic mild cognitive impairment (aMCI) and dementia of Alzheimer's type (DAT). The results showed that the Thai NPI-Q had good validity and reliability, and cognitive performance was significantly correlated with NPI-Q scores. Some individuals with aMCI may progress to probable dementia.
FRONTIERS IN NEUROLOGY
(2023)
Article
Neurosciences
Alain D. Dekker, Aurora M. Ulgiati, Henk Groen, Vincent A. Boxelaar, Silvia Sacco, Segolene Falquero, Angelo Carfi, Antonella di Paola, Bessy Benejam, Silvia Valldeneu, Roelie Fopma, Marjo Oosterik, Marloes Hermelink, Gonny Beugelsdijk, Mieke Schippers, Hepie Henstra, Martine Scholten-Kuiper, Judith Willink-Vos, Lisa de Ruiter, Liesbeth Willems, Anneke Loonstra-de Jong, Antonia M. W. Coppus, Marleen Tollenaere, Juan Fortea, Graziano Onder, Anne-Sophie Rebillat, Debby Van Dam, Peter P. De Deyn
Summary: The study aimed to optimize and further study the discriminative ability and reliability of the BPSD assessment scale BPSD-DS II for individuals with Down syndrome (DS). Results showed significant changes in frequency and severity of anxious, sleep-related, irritable, apathetic, depressive, and eating/drinking behaviors among DS, DS+Q, and DS+AD groups. These changes may serve as early signals of Alzheimer's disease dementia in DS.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Medicine, Research & Experimental
Wei Jiang, Zhenxia Wu, Li Wen, Liu Sun, Meiqun Zhou, Xiaochen Jiang, Yaxing Gui
Summary: The study found that high-frequency TMS has the advantages of fast results, good efficacy, and high safety for treating psychobehavioral abnormalities in AD patients, and can further improve cognitive function.
ADVANCES IN THERAPY
(2022)
Article
Clinical Neurology
Valentina Lagana, Francesco Bruno, Natalia Altomari, Giulia Bruni, Nicoletta Smirne, Sabrina Curcio, Maria Mirabelli, Rosanna Colao, Gianfranco Puccio, Francesca Frangipane, Chiara Cupidi, Giusy Torchia, Gabriella Muraca, Antonio Malvaso, Desiree Addesi, Alberto Montesanto, Raffaele Di Lorenzo, Amalia Cecilia Bruni, Raffaele Maletta
Summary: Neuropsychiatric or behavioral and psychological symptoms of dementia (BPSD) are common in patients with dementia and should not be underestimated. This study examines the prevalence and natural history of BPSD in patients with behavioral variant of frontotemporal dementia (bvFTD) and Alzheimer's disease (AD). The results show that BPSD affect a high percentage of dementia patients and have different profiles in the two types of dementia.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neurosciences
Emilia Schwertner, Joana B. Pereira, Hong Xu, Juraj Secnik, Bengt Winblad, Maria Eriksdotter, Katarina Nagga, Dorota Religa
Summary: This study characterizes the behavioral and psychological symptoms of dementia (BPSD) in different types of dementia in long-term care facilities. The results show that there are variations in symptom risks between different types of dementia, but aberrant motor behavior, agitation, and irritability are common symptoms among all types of dementia patients.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Psychiatry
Yujiro Kuroda, Taiki Sugimoto, Nanae Matsumoto, Kazuaki Uchida, Yoshinobu Kishino, Claudia Kimie Suemoto, Takashi Sakurai
Summary: Preventive measures to limit the spread of COVID-19 have led to social isolation, negatively impacting the physical and mental health of older adults, especially those with dementia. This study found that certain behavioral and psychological symptoms of dementia (BPSD) were more prevalent during the pandemic, with higher levels of night waking in the mild group and increased physical attacks in the moderate/severe group. These findings highlight the importance of screening and interventions for BPSD in dementia patients during COVID-19.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Geriatrics & Gerontology
Wei-Chih Yeh, Chung-Yao Hsu, Kuan-Ying Li, Ching-Fang Chien, Ling-Chun Huang, Yuan-Han Yang
Summary: Behavioral and psychological symptoms of dementia (BPSD) are common in patients with Alzheimer's disease (AD) and are associated with subclinical epileptiform discharge (SED). SED may not be a direct cause of BPSD but can affect its manifestation.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2023)
Article
Psychiatry
Zhen Yang, Ying Zhou
Summary: Repetitive transcranial magnetic stimulation (rTMS) has a positive effect on cognitive function and Behavioral And Psychological Symptoms Of Dementia, but adverse reactions are inevitable. Personalized treatment according to the patient's situation can reduce the occurrence of adverse reactions.
Article
Neurosciences
Natalia Altomari, Francesco Bruno, Valentina Lagana, Nicoletta Smirne, Rosanna Colao, Sabrina Curcio, Raffaele Di Lorenzo, Francesca Frangipane, Raffaele Maletta, Gianfranco Puccio, Amalia Cecilia Bruni
Summary: This study compared the behavioral and psychological symptoms between early-onset and late-onset Alzheimer's disease patients, and found that early-onset patients had a higher overall prevalence of symptoms and a later onset compared to late-onset patients. The manifestation of symptoms and sub-syndromes also differed between the two groups at different stages. However, there were no significant differences in the severity of symptoms.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Geriatrics & Gerontology
Fu-Rong Li, Hai-Lian Yang, Rui Zhou, Jia-Zhen Zheng, Guo-Chong Chen, Xiao-Xiang Wu, Meng-Chen Zou, Jing-Ya Wang, Qiang Fu, Xian-Bo Wu
Summary: This study investigated the influence of diabetes duration and glycemic control on the risk of incident dementia. The findings showed that individuals with diabetes have a higher risk of dementia compared to those with normal glucose levels, and this risk increases with longer duration of diabetes. Additionally, it was found that both longer diabetes duration and poor glycemic control were associated with the highest risk of dementia, highlighting the importance of considering both factors in dementia risk assessments for diabetic patients.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Review
Clinical Neurology
Mario F. Mendez
Summary: Alzheimer's disease and related dementias can cause significant distress, impairment, and caregiver burden in aging populations due to the Behavioral and Psychological Symptoms of Dementia (BPSD). Effective dementia care requires understanding both non-pharmacological and pharmacological interventions for BPSD. It is important for clinicians to be familiar with treatment options, especially related to psychoactive medications, in this vulnerable population.
CURRENT TREATMENT OPTIONS IN NEUROLOGY
(2022)
Article
Geriatrics & Gerontology
Masaki Shinohara, Kana Matsuda, Yuichiro Ii, Ken-ichi Tabei, Naoko Nakamura, Yoshinori Hirata, Hidehiro Ishikawa, Hirofumi Matsuyama, Keita Matsuura, Masayuki Maeda, Hidekazu Tomimoto, Akihiro Shindo
Summary: This study investigated the relationship between behavioral and psychological symptoms (BPS) and cerebral small vessel disease (SVD) in patients with mild cognitive impairment (MCI) or mild dementia. The results showed that patients with BPS had worse clinical dementia ratings, reduced psychomotor speed, higher modified CAA-SVD scores, and larger numbers of cerebral microbleeds (CMBs). Therefore, preventing these brain lesions may help mitigate the risk of BPS.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Yuko Goto, Hisayuki Miura, Daisuke Son, Isabelle Scholl, Levente Kriston, Martin Haerter, Kotaro Sato, Tesshu Kusaba, Hidenori Arai
Summary: The study aimed to create a Japanese version of the SDM-Q-Doc scale to assess SDM from the perspective of physicians, confirm its internal consistency and validity, and identify the positive role of nurse's attendance in physician-patient consultations in facilitating SDM.
Article
Social Work
Yoshihisa Hirakawa, Kaoruko Aita, Mitsunori Nishikawa, Hidenori Arai, Hisayuki Miura
Summary: Completing advance care planning for older COPD patients living alone presents challenges such as information sharing, patient readiness, desired place of death, economic constraints, and care at the time of and after death. Social work knowledge and skills are crucial in facilitating the completion of ACP for this population.
JOURNAL OF SOCIAL WORK IN END-OF-LIFE & PALLIATIVE CARE
(2022)
Review
Environmental Sciences
Yasuhiro Yamaguchi, K. M. Saif-Ur-Rahman, Motoko Nomura, Hiromitsu Ohta, Yoshihisa Hirakawa, Takashi Yamanaka, Satoshi Hirahara, Hisayuki Miura
Summary: Opioids can alleviate breathlessness and improve the quality of life in patients with chronic obstructive pulmonary disease. Recent studies suggest that regular oral opioid use can decrease the severity of breathlessness, and morphine or codeine show significant acute effects. Further research is needed to optimize prescription methods and minimize adverse effects.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Yoshihisa Hirakawa, Kaoruko Aita, Mitsunori Nishikawa, Hidenori Arai, Hisayuki Miura
Summary: This study aimed to identify tips for clinicians managing ethical challenges in advance care planning (ACP) practices. By analyzing the content of nine ACP textbooks, two major themes were identified: interprofessional ethics and informed consent. The findings suggested recommendations for managing ethical challenges in ACP.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Health Policy & Services
Yuko Goto, Hisayuki Miura
Summary: Shared decision-making in Japan is still in its early stages, with challenges in supporting older individuals in treatment decisions. The importance of decision support and patient involvement is not widely recognized, but efforts in clinical settings are underway to address this. Policy guidelines and academic proposals are expected to increase awareness and support for decision-making in the future.
ZEITSCHRIFT FUR EVIDENZ FORTBILDUNG UND QUALITAET IM GESUNDHEITSWESEN
(2022)
Article
Environmental Sciences
Yuko Goto, Hisayuki Miura
Summary: Due to the aging population in Japan, the government is attempting to link the healthcare and long-term care delivery systems. This study used the soft systems methodology (SSM) to visualize the challenges and perspectives of interested parties in different communities. By organizing information using the SSM, the study identified the current situations, issues, challenges, and proposed solutions regarding the linkage between the two systems.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Yuko Goto, Hisayuki Miura, Yasuhiro Yamaguchi, Joji Onishi
Summary: This study evaluated the impact of a novel training program that incorporated shared decision making (SDM) skills training into an advance care planning (ACP) training course. The program significantly improved healthcare professionals' knowledge, skills, attitudes, and confidence to initiate ACP.
BMC PALLIATIVE CARE
(2022)
Article
Endocrinology & Metabolism
Taiki Sugimoto, Haruhiko Tokuda, Hisayuki Miura, Shuji Kawashima, Takafumi Ando, Yujiro Kuroda, Nanae Matsumoto, Kosuke Fujita, Kazuaki Uchida, Yoshinobu Kishino, Takashi Sakurai
Summary: This study aimed to examine the association between continuous glucose monitoring (CGM)-derived metrics and cognitive performance in older adults with type 2 diabetes (T2D). The results showed that the mean sensor glucose level derived from CGM was negatively associated with cognitive performance, while the time in range (TIR) was positively associated with cognitive function.
DIABETES OBESITY & METABOLISM
(2023)
Article
Geriatrics & Gerontology
Takashi Yamanaka, Kiwami Kidana, Yasuhiro Yamaguchi, Satoshi Hirahara, Yoshihisa Hirakawa, Maiko Mizuki, Hidenori Arai, Masahiro Akishita, Hisayuki Miura
Summary: This study investigates the practices and opinions of physicians providing home visits regarding palliative care for older adults with respiratory symptoms due to non-malignant diseases in Japan. The study found a discrepancy between the proportion of physicians who considered palliative care as effective and those who prescribed it.
GERIATRICS & GERONTOLOGY INTERNATIONAL
(2022)
Article
Environmental Sciences
Yuko Goto, Hisayuki Miura, Naomi Ito
Summary: The Japanese long-term care insurance system, implemented in 2000, aims to improve the quality of care management. This study investigates the impact of the chief care manager certificate on coordination with hospitals. Results show that certified chief care managers have greater confidence in providing hospitalization and discharge support to their patients. However, there is no significant difference between chief and normal care managers in terms of these activities.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Yuko Goto, Hisayuki Miura
Summary: To support patients in complex decision-making, a team is needed comprising specialists, patients, and family members. This study aimed to validate a new measure for interprofessional shared decision-making in the context of multidisciplinary teams. The measure showed good fit and internal consistency, and it can be used to evaluate the process of shared decision-making involving multidisciplinary professionals.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Hisayuki Miura, Yuko Goto
Summary: This study investigated the utility of the Controlling Nutritional Status (CONUT) score as a prognostic factor for older patients without cancer receiving home medical care. The results showed that the CONUT score could be used to predict overall mortality in these patients. It is expected to be a simpler and cheaper screening tool for assessing the nutritional status in the field of home medical care.
Article
Health Care Sciences & Services
Yuko Goto, Hisayuki Miura
Summary: This study evaluated an advanced care planning (ACP) training program that incorporated online skills in shared decision making (SDM). The New World Kirkpatrick Model was used to assess the efficacy of the program, which showed that participants were satisfied with the training, experienced some difficulties, and received support from their workplaces. SDM skills significantly improved, and a majority of the participants expressed willingness to become ACP education facilitators in the future.
Article
Endocrinology & Metabolism
Taiki Sugimoto, Haruhiko Tokuda, Hisayuki Miura, Shuji Kawashima, Takuya Omura, Takafumi Ando, Yujiro Kuroda, Nanae Matsumoto, Kosuke Fujita, Kazuaki Uchida, Yoshinobu Kishino, Takashi Sakurai
DIABETES OBESITY & METABOLISM
(2023)
Article
Urology & Nephrology
Kazuyoshi Okada, Ken Tsuchiya, Ken Sakai, Takahiro Kuragano, Akiko Uchida, Kazuhiko Tsuruya, Tadashi Tomo, Chieko Hamada, Masafumi Fukagawa, Yoshindo Kawaguchi, Yuzo Watanabe, Kaoruko Aita, Yoshitatsu Ogawa, Junji Uchino, Hirokazu Okada, Yutaka Koda, Yasuhiro Komatsu, Hisamitsu Sato, Motoshi Hattori, Toru Baba, Mamiko Matsumura, Hisayuki Miura, Jun Minakuchi, Hidetomo Nakamoto
Summary: The JSDT revised the proposal in 2020 to guide healthcare teams in providing the best healthcare management and care respecting the patient's will through advance care planning and shared decision making. This includes conservative kidney management for all end-stage kidney disease patients, regardless of terminal stage or dementia. The proposal is consensus-based rather than evidence-based, which means healthcare teams may not be legally exempt if implementing the policies results in the patient's death.
RENAL REPLACEMENT THERAPY
(2021)
