Minimally invasive genomic and transcriptomic profiling of visceral cancers by next-generation sequencing of circulating exosomes

Whole genomes redefine the mutational landscape of pancreatic cancer

(2015) Nicola Waddell et al.   NATURE

Exome Sequencing of Cell-Free DNA from Metastatic Cancer Patients Identifies Clinically Actionable Mutations Distinct from Primary Disease

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Neoantigens in cancer immunotherapy

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The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas

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Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA

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Double-stranded DNA in exosomes: a novel biomarker in cancer detection

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Identification of Double-stranded Genomic DNA Spanning All Chromosomes with MutatedKRASandp53DNA in the Serum Exosomes of Patients with Pancreatic Cancer

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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

(2014) Marco Gerlinger et al.   NATURE GENETICS

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

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Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

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Multiplex Picodroplet Digital PCR to Detect KRAS Mutations in Circulating DNA from the Plasma of Colorectal Cancer Patients

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Exosomes in tumor microenvironment influence cancer progression and metastasis

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Signatures of mutational processes in human cancer

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Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

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Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors

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Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing

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Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs

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Effect of the overexpression of BRCA2 unclassified missense variants on spontaneous homologous recombination in human cells

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An Emerging Entity: Pancreatic Adenocarcinoma Associated with a Known BRCA Mutation: Clinical Descriptors, Treatment Implications, and Future Directions

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High Fragmentation Characterizes Tumour-Derived Circulating DNA

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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

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Circulating microRNAs as stable blood-based markers for cancer detection

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