Journal
GENETICS RESEARCH
Volume 94, Issue 5, Pages 267-274Publisher
HINDAWI LTD
DOI: 10.1017/S0016672312000468
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Funding
- NIH grant [GM 075091]
- Leverhulme Trust
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In previous analyses, the variation in actual, or realized, relationship has been derived as a function of map length of chromosomes and type of relationship, the variation being greater the shorter the total chromosome length and the coefficient of variation being greater the more distant the relationship. Here, the results are extended to allow for the relatives' ancestor being inbred. Inbreeding of a parent reduces variation in actual relationship among its offspring, by an amount that depends on the inbreeding level and the type of mating that led to that level. For descendants of full-sibs, the variation is reduced in later generations, but for descendants of half-sibs, it is increased.
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