Downsizing genomic medicine: Approaching the ethical complexity of whole-genome sequencing by starting small

Overview of personalized medicine in the disease genomic era

(2011) Kyung-Won Hong et al.   BMB Reports

Advances in Whole Genome Sequencing Technology

(2011) Jianhua Zhao et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Consensus Statement: Chromosomal Microarray Is a First-Tier Clinical Diagnostic Test for Individuals with Developmental Disabilities or Congenital Anomalies

(2010) David T. Miller et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Health-Care Referrals from Direct-to-Consumer Genetic Testing

(2010) Monica A. Giovanni et al.   Genetic Testing and Molecular Biomarkers

The Impact of Whole Genome Sequencing on Model System Genetics: Get Ready for the Ride

(2010) O. Hobert   GENETICS

Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia

(2010) J. Rios et al.   HUMAN MOLECULAR GENETICS

Informing family members about a hereditary predisposition to cancer: attitudes and practices among clinical geneticists

(2010) Y. H. Stol et al.   JOURNAL OF MEDICAL ETHICS

Whole-genome association studies for multigenic diseases: ethical dilemmas arising from commercialization--the case of genetic testing for autism

(2010) B. R. Jordan et al.   JOURNAL OF MEDICAL ETHICS

Challenges in the clinical application of whole-genome sequencing

(2010) Kelly E Ormond et al.   LANCET

The personal genome—the future of personalised medicine?

(2010) Nilesh J Samani et al.   LANCET

Clinical assessment incorporating a personal genome

(2010) Euan A Ashley et al.   LANCET

Effect of genome-wide association studies, direct-to-consumer genetic testing, and high-speed sequencing technologies on predictive genetic counselling for cancer risk

(2010) Michael R Speicher et al.   LANCET ONCOLOGY

Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study

(2010) P A Ho et al.   LEUKEMIA

Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations

(2010) Kaya Bilgüvar et al.   NATURE

Personalized genomic information: preparing for the future of genetic medicine

(2010) Alan E. Guttmacher et al.   NATURE REVIEWS GENETICS

Genomic Medicine — An Updated Primer

(2010) W. Gregory Feero et al.   NEW ENGLAND JOURNAL OF MEDICINE

Whole-Genome Sequencing in a Patient with Charcot–Marie–Tooth Neuropathy

(2010) James R. Lupski et al.   NEW ENGLAND JOURNAL OF MEDICINE

Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing

(2010) J. C. Roach et al.   SCIENCE

Offering Individual Genetic Research Results: Context Matters

(2010) L. M. Beskow et al.   Science Translational Medicine

Personal genome research : what should the participant be told?

(2010) Amy L. McGuire et al.   TRENDS IN GENETICS

Ethical issues raised by common copy number variants and single nucleotide polymorphisms of certain and uncertain significance in general medical practice

(2010) Arthur L Beaudet   Genome Medicine

The 1000 Genomes Project: new opportunities for research and social challenges

(2010) Marc Via et al.   Genome Medicine

Evaluating the utility of personal genomic information

(2009) Morris W Foster et al.   GENETICS IN MEDICINE

Is there a duty to share genetic information?

(2009) S M Liao   JOURNAL OF MEDICAL ETHICS

Sequencing technologies — the next generation

(2009) Michael L. Metzker   NATURE REVIEWS GENETICS

Beyond odds ratios — communicating disease risk based on genetic profiles

(2009) Peter Kraft et al.   NATURE REVIEWS GENETICS

Microarray Technology and Applications in the Arena of Genome-Wide Association

(2008) S. F. A. Grant et al.   CLINICAL CHEMISTRY

Applications of next-generation sequencing technologies in functional genomics

(2008) Olena Morozova et al.   GENOMICS

An Unwelcome Side Effect of Direct-to-Consumer Personal Genome Testing

(2008) Amy L. McGuire et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Letting the Genome out of the Bottle — Will We Get Our Wish?

(2008) David J. Hunter et al.   NEW ENGLAND JOURNAL OF MEDICINE