Article
Obstetrics & Gynecology
Linda Brubaker, Erica Marsh, Marcelle Cedars, Dee Fenner, Amy Murtha, Barbara Goff, Dineo Khabele
Summary: The advancement of women leaders in obstetrics and gynecology does not match the changes in the physician workforce. Gender equity should be a core value in the culture of obstetrics and gynecology, and actions should be taken to prioritize and demonstrate commitment to gender equity. This commentary proposes principles and leadership practices to promote gender equity in academic leadership roles within obstetrics and gynecology.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Medicine, General & Internal
Agustin Diaz-Rodriguez, Leandro Feliz-Matos, Carlos Bienvenido Ruiz Matuk
Summary: The study identified maternal age over 35, previous preterm birth, family history of preterm births, and premature rupture of membranes as independent risk factors for preterm birth. Adolescence, pregnancy weight gain, and prenatal consultations were found to be protective factors. Although the prevalence of premature births in this study was 25%, there may have been bias.
Article
Medicine, General & Internal
Mulualem Silesh, Tesfanesh Lemma, Samuel Abdu, Belete Fenta, Mesfin Tadese, Birhan Tsegaw Taye
Summary: This study aimed to assess the prevalence of immediate postpartum family planning utilization and the associated factors among postpartum women in the North Shoa Zone area of Ethiopia. The results showed that less than a quarter of women used immediate postpartum family planning. Factors associated with utilization included women's age, planning status of pregnancy, reproductive intention, partner support, attitude towards family planning, and maternal satisfaction with intrapartum care.
Review
Medicine, General & Internal
Abdullah Pandor, Jahnavi Daru, Beverley J. Hunt, Gill Rooney, Jean Hamilton, Mark Clowes, Steve Goodacre, Catherine Nelson-Piercy, Sarah Davis
Summary: This study conducted a systematic review to assess the accuracy of risk assessment models (RAMs) in predicting venous thromboembolism (VTE) risk during pregnancy and the early postnatal period. The results suggest that the available data have weak designs and limited generalisability, making the estimates of prognostic accuracy uncertain.
Article
Medicine, General & Internal
Becky Liu, Emily Marler, Basky Thilaganathan, Amarnath Bhide
Summary: This study aims to assess the feasibility, reliability, and accuracy of the Femom (NIFECG) device by comparing its outputs to cCTG monitoring. It is a single-centred, prospective pilot study taking place in a tertiary maternity unit. The study will compare the STV and baseline FHR values produced by both devices and investigate the impact of maternal and fetal characteristics on their effectiveness.
Article
Obstetrics & Gynecology
Joselle O'Brien, Camille A. Clare
Summary: Race is a social construct that has changed in meaning over time, and racist beliefs in medicine have perpetuated these ideas. This commentary compares race-based medicine to race-conscious medicine, highlighting the importance of racism as a key factor in illness and health. Racism in obstetrics and gynecology has deep historical roots, and the use of race in clinical decision-making tools should be eliminated. Research that examines the complexities of health disparities and their impact on clinical outcomes is crucial for race-conscious approaches in medicine.
CLINICAL OBSTETRICS AND GYNECOLOGY
(2023)
Article
Medicine, General & Internal
Tatsuya Arakaki, Junichi Hasegawa, Akihiko Sekizawa, Tomoaki Ikeda, Isamu Ishiwata, Katsuyuki Kinoshita
Summary: This study found that severe COVID-19 in pregnant women is associated with gestational age and maternal age, and the rate of preterm birth due to infection is significantly higher in severe cases.
Article
Obstetrics & Gynecology
Georgios Doulaveris, Kavita Vani, Gabriele Saccone, Suneet P. Chauhan, Vincenzo Berghella
Summary: This study aimed to evaluate the quality of published obstetrical randomized controlled trials and identify factors associated with publication in different journals. The majority of obstetrical trials were published in obstetrics and gynecology journals, with a smaller proportion published in weekly medical journals. Trials published in weekly medical journals differed from those published in obstetrics and gynecology journals in terms of sample size, funding sources, multicenter participation, international scope, and blinding. However, there were no differences between the two types of journals in terms of trial type and quality characteristics.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2022)
Review
Medicine, General & Internal
Kana Saito, Etsuko Nishimura, Erika Ota, Fumihiko Namba, Toshiyuki Swa, Jenny Ramson, Tina Lavin, Jenny Cao, Joshua Peter Vogel
Summary: This study synthesized the available evidence on the efficacy of antenatal corticosteroid therapy in women at risk of preterm birth with pregestational/gestational diabetes, chorioamnionitis, fetal growth restriction, or planned caesarean section. The results suggest that antenatal corticosteroid therapy may reduce neonatal mortality, intraventricular hemorrhage, and respiratory distress syndrome in women with chorioamnionitis. Among women with fetal growth restriction, antenatal corticosteroid therapy may reduce the use of surfactant, mechanical ventilation, and oxygen therapy, but may increase the risk of hypoglycemia. There is limited evidence for women with diabetes and those undergoing planned caesarean section, and further research is needed for validation.
Article
Medicine, General & Internal
Simin Li, Yi Li, Qiu Liang, Wen-Jie Yang, Rui Zi, Xuyi Wu, Chunping Du, Yan Jiang
Summary: This study aims to investigate the effects of a moderate-to-high-intensity tele-exercise intervention using a tele-rehabilitation app on vertical fracture and fall prevention in women at high risk of osteoporotic fractures.
Article
Medicine, General & Internal
Jacqueline Powell, Evelyn Fuentes-Rivera, Blair Darney
Summary: The study found that although over 60% of both high-risk and normal-risk women received immediate postpartum contraception, a greater proportion of high-risk women received a method. However, in multivariable models, there were no significant differences in the receipt of any modern method or tier 1 method by risk group after accounting for sociodemographic and clinical factors.
Article
Obstetrics & Gynecology
Lisa M. Painter, Keirstyn A. Biggans, Chaton T. Turner
Summary: The likelihood of medical malpractice claims is higher for obstetrics and gynecology physicians compared to other medical specialties. This article discusses the principles of health care risk management, the role of risk managers, and the importance of risk management in mitigating risks for these physicians. It covers topics such as medical record documentation, disclosure of adverse events, second victim programs, grievance management techniques, alternative dispute resolution, regulatory inquiries, product failures, and electronic media strategies. Ultimately, health care risk management serves as a tool for claim avoidance and provider protection for physicians.
CLINICAL OBSTETRICS AND GYNECOLOGY
(2023)
Article
Medicine, General & Internal
Stinne Hogh, Line Thellesen, Thomas Bergholt, Ane Lilleore Rom, Marianne Johansen, Jette Led Sorensen
Summary: The study found that some obstetric events occur extremely rarely, making it difficult to acquire and maintain the clinical skills needed to manage them through clinical practice alone. By assessing the frequency of healthcare professionals attending obstetric emergencies, the study highlights the need for supplementary educational initiatives and interventions to learn and maintain clinical skills.
Article
Hematology
Andre Luiz Malavasi Longo de Oliveira, Renata Fernanda de Oliveira Pereira, Leandro Barile Agati, Camilla Moreira Ribeiro, Gabrielly Yukimi Kawamura Suguiura, Claudia Helena Cioni, Marilsa Bermudez, Marcia Bermudez Pirani, Roberto Augusto Caffaro, Valter Castelli, Valeria Cristina Resende Aguiar, Giuliano Giova Volpiani, Adilson Paschoa, Ariane Vieira Scarlatelli Macedo, Pedro Gabriel Melo Silva, Joao Carlos de Campos Guerra, Jawed Fareed, Renato Delascio Lopes, Eduardo Ramacciotti
Summary: Rivaroxaban and enoxaparin have similar efficacy and safety in preventing venous thromboembolism after major gynecological cancer surgery.
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
(2022)
Article
Multidisciplinary Sciences
Wonkyo Shin, Tae Young Ham, Young Ran Park, Myong Cheol Lim, Young-Joo Won
Summary: The 2018 FIGO cervical cancer staging system introduced new stage subdivisions and lymph node status considerations, showing better survival in stage IIIC compared to stage IIIA/B. Primary tumor size was found to be related to survival outcomes, highlighting potential improvements in staging accuracy for advanced cervical cancer.
SCIENTIFIC REPORTS
(2021)
Article
Surgery
Matthew Cooper, David B. Leeser, Stuart M. Flechner, Jennifer L. Beaumont, Amy D. Waterman, Patrick W. Shannon, Matthew Ronin, Garet Hil, Jeffrey L. Veale
Summary: The National Kidney Registry's Advanced Donation Program allows living donors to donate in advance and receive a voucher for a future transplant. A Monte Carlo simulation study suggests that NKR should be able to meet the increasing demand for voucher redemptions over the next 50 years.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Surgery
Amy D. Waterman, John D. Peipert, Yujie Cui, Jennifer L. Beaumont, Andrea Paiva, Amanda F. Lipsey, Crystal S. Anderson, Mark L. Robbins
Summary: Individualized education plans can enhance patients' readiness and knowledge about living and deceased donor kidney transplants, and promote their proactive pursuit of transplantation. The study indicates that a focused and coordinated educational effort can improve transplant-seeking behaviors and waitlisting rates among patients.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Health Care Sciences & Services
Kristen Curcija, Linda Zittleman, Mary Fisher, Donald E. Nease, L. Miriam Dickinson, Dionisia de la Cerda, Christin Sutter, Jen Ancona, James Rank, John M. Westfall
Summary: This study aims to increase awareness and promote positive attitudes towards OUD and MAT among rural community members through the development of community-based interventions. The findings show that exposure to these interventions is associated with beliefs such as the acknowledgement of opioid abuse as a problem in rural areas, the recognition of opioid addiction as a chronic disease, and the belief that OUD can be treated locally.
JOURNAL OF RURAL HEALTH
(2022)
Article
Rheumatology
Jennifer L. Beaumont, Elizabeth S. Davis, Jeffrey R. Curtis, David Cella, Huifeng Yun
Summary: The study estimated meaningful change thresholds for fatigue and pain interference in rheumatoid arthritis patients, finding the MCT range to be 1-2 points and showing low correlations between change scores and retrospective ratings.
JOURNAL OF RHEUMATOLOGY
(2021)
Article
Oncology
Yifan Shen, Ananda Sen, D. Kim Turgeon, Jianwei Ren, Gillian Graifman, Mack T. Ruffin, William L. Smith, Dean E. Brenner, Zora Djuric
Summary: Personalized omega-3 fatty acid dosing may reduce colonic inflammation, with blood fatty acid changes reflecting this effect, but further optimization is needed for predictive models.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2022)
Letter
Hematology
Larysa Sanchez, Xavier Leleu, Jennifer L. Beaumont, Hailin Yu, Stacie Hudgens, Maryana Simonova, Holger W. Auner, Hang Quach, Sosana Delimpasi, Ivan Spicka, Ludek Pour, Iryna Kriachok, Meletios A. Dimopoulos, Ganna Usenko, Roman Hajek, Reuben Benjamin, Dinesh Kumar Sinha, Christopher Venner, Thomas Illmer, Mamta Krishnan Garg, Don Ambrose Stevens, Sundar Jagannath, Moshe Levy, Larry D. Anderson, Nizar Jacques Bahlis, Thierry Facon, Michele Cavo, Yi Chai, Xiwen Ma, Shijie Tang, Hoyee Leong, Jatin Shah, Sharon Shacham, Michael Kauffman, Paul Richardson, Sebastian Grosicki
AMERICAN JOURNAL OF HEMATOLOGY
(2021)
Editorial Material
Primary Health Care
Donald Nease, Micbelle Greiver
ANNALS OF FAMILY MEDICINE
(2021)
Article
Health Policy & Services
Jennifer L. Moss, Madyson Popalis, Sarah I. Ramirez, Alexis Reedy-Cooper, Mack T. Ruffin
Summary: Research found that cancer screening rates in the US can be improved, with different screening disparities across county types, segregation was positively associated with colorectal cancer screening rates in non-metropolitan counties but not in metropolitan counties. This study provides guidance for future cancer screening interventions in underserved communities.
JOURNAL OF COMMUNITY HEALTH
(2022)
Article
Primary Health Care
Linda Zittleman, Kristen Curcija, Donald E. Nease, Mary Fisher, L. Miriam Dickinson, John F. Thomas, Ashley Espinoza, Christin Sutter, Jennifer Ancona, Jodi Summers Holtrop, John M. Westfall
Summary: The study aimed to increase rural PCPs providing buprenorphine treatment for OUD through practice team training. Results showed a significant improvement in treatment implementation and delivery, with an increase in the number of practices providing or referring patients for treatment, and a greater number of people with a buprenorphine prescription in the study region compared to the rest of the state.
ANNALS OF FAMILY MEDICINE
(2022)
Article
Genetics & Heredity
Catharine Wang, Haibo Lu, Deborah J. Bowen, Ziming Xuan
Summary: This study examined the uptake of genetic counseling and testing after the implementation of a digital cancer genetic risk assessment program at 27 healthcare sites in 10 states. The study found that 16% of the high-risk individuals proceeded with genetic testing. The findings highlight the significant impact of different clinical workflows on the uptake of genetic testing.
GENETICS IN MEDICINE
(2023)
Article
Rheumatology
George J. Greene, Jennifer L. Beaumont, Emily J. Bacalao, Azra Muftic, Karen Kaiser, Amy R. Eisenstein, Arthur M. Mandelin, David Cella, Eric M. Ruderman
Summary: This study evaluated the effect of a patient-centered "treat-to-target" (T2T) rheumatoid arthritis (RA) disease management approach on patient outcomes and satisfaction with care. The study found that integrating the PROMIS assessment system into RA treatment can improve disease activity and increase patient satisfaction.
JOURNAL OF RHEUMATOLOGY
(2023)
Article
Health Care Sciences & Services
E. J. Dusic, Deborah J. Bowen, Robin Bennett, Kevin C. Cain, Tesla Theoryn, Mariebeth Velasquez, Elizabeth Swisher, Jeannine M. Brant, Brian Shirts, Catharine Wang
Summary: This study found that socioeconomic status affects individuals' interest in pursuing hereditary cancer genetic testing, with factors such as education and household income being related to the level of interest.
Article
Respiratory System
Fernando Diaz del Valle, Patricia B. Koff, Sung-Joon Min, Jonathan K. Zakrajsek, Linda Zittleman, Douglas H. Fernald, Andrea Nederveld, Donald E. Nease, Alexis R. Hunter, Eric J. Moody, Kay Miller Temple, Jenny L. Niblock, Chrysanne Grund, Tamara K. Oser, K. Allen Greiner, R. William Vandivier
Summary: Rural primary care providers face significant challenges when caring for COPD patients, including barriers related to diagnosis, treatment, and access to resources. These challenges should be targeted in future interventions to improve COPD outcomes.
CHRONIC OBSTRUCTIVE PULMONARY DISEASES-JOURNAL OF THE COPD FOUNDATION
(2021)
Article
Health Care Sciences & Services
Alexander O'Donovan, Sean M. Oser, Jessica Parascando, Arthur Berg, Donald E. Nease, Tamara K. Oser
Summary: Research shows that primary care providers (PCPs) are willing to prescribe advanced diabetes technologies, particularly fully automated artificial pancreas systems (APS), and believe that this can expand the benefits to patients, reducing treatment disparities between endocrinologists and PCPs.
JOURNAL OF PATIENT-CENTERED RESEARCH AND REVIEWS
(2021)
Article
Genetics & Heredity
Molly McGuinness, Emily Fassi, Catharine Wang, Claire Hacking, Victoria Ellis
Summary: This study found that less than half of surveyed cancer genetic counselors had ordered breast cancer PRS, with only a third reporting that it had changed their medical management recommendations. The majority of counselors had not ordered PRS due to reasons such as lack of clinical guidelines, insufficient evidence of clinical utility, and limited availability for patients of non-European ancestry. Only a small percentage of genetic counselors who had not ordered PRS believed they would order it in the future.
JOURNAL OF GENETIC COUNSELING
(2021)
Article
Genetics & Heredity
Katerina S. Kucera, Beth Lincoln Boyea, Brooke Migliore, Sarah Nelson Potter, Veronica R. Robles, Oksana Kutsa, Heidi Cope, Katherine C. Okoniewski, Anne Wheeler, Catherine W. Rehder, Edward C. Smith, Holly L. Peay
Summary: Screening for elevated CK-MM levels in dried blood spots is a feasible method to identify newborns with DMD. Including specific cutoffs, repeat testing, and genetic sequencing can improve the accuracy and sensitivity of screening.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Madeline Currey, Ilana Solomon, Sarah Mcgraw, Jenny Shen, Francisco Munoz, Ernesto Sosa, Vanessa Puello-Lozano, Sam Wing, Lisa Lopez, Michelle Afkhami, Janine Lobello, Szabolcs Szelinger, Stacy W. Gray
Summary: This study conducted qualitative interviews with cancer patients and providers to identify gaps in clinical care and propose care delivery solutions for the return of secondary germline findings. The responses of patients varied depending on the amount of pre-test counseling they received, and providers identified insufficient clinic time as a major barrier to pretest education. Online support tools and standardized pre-test education models were favored by providers. There were differing perspectives on how pre-test education should be integrated into clinical workflows, but agreement on the inclusion of differences between somatic and germline testing, likelihood of medically actionable findings, and the possibility of being referred to a genetics provider.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Kiely N. James, Shimul Chowdhury, Yan Ding, Sergey Batalov, Kelly Watkins, Yong Hyun Kwon, Lucitia Van Der Kraan, Katarzyna Ellsworth, Stephen F. Kingsmore, Lucia Guidugli
Summary: This study used genome sequencing to detect a wide range of copy-number variants (CNVs) and other non-single nucleotide variant/indel variant types. These genetic alterations accounted for 15.8% of reported variants, with deletions being the most common type. The study also found that additional genetic tests were ordered in some cases, but failed to report the variants detected by genome sequencing.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Asem Berkalieva, Nicole R. Kelly, Ashley Fisher, Samuel F. Hohmann, Monisha Sebastin, Miranda Di Biase, Katherine E. Bonini, Priya Marathe, Jacqueline A. Odgis, Sabrina A. Suckiel, Michelle A. Ramos, Rosamond Rhodes, Noura S. Abul-Husn, John M. Greally, Carol R. Horowitz, Melissa P. Wasserstein, Eimear E. Kenny, Bruce D. Gelb, Bart S. Ferket
Summary: The study aims to understand the effects of returning diagnostic sequencing results on clinical actions and economic outcomes for pediatric patients with suspected genetic disorders. The results showed that patients with positive findings were more likely to receive specialist consultation, but there were no significant increases in overall physician services and costs. More large-scale studies are needed to confirm these findings.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Kirstine Stochholm, Camilla Holmgard, Shanlee M. Davis, Claus H. Gravholt, Agnethe Berglund
Summary: This study assessed the incidence, prevalence, and age at diagnosis of individuals with 45,X/46,XY mosaicism and described the associated mortality pattern. The study found an increasing incidence of 45,X/46,XY mosaicism in males and a stable incidence in females. Males were diagnosed at an older age than females. Additionally, 45,X/46,XY mosaicism was associated with increased all-cause mortality.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Yunjia Chen, Ender Karaca, Nathaniel H. Robin, Dana Goodloe, Ali Al-Beshri, S. Joy Dean, Anna C. E. Hurst, Andrew J. Carroll, Fady M. Mikhail
Summary: This study confirms the association between DLG2 intragenic deletions and neurodevelopmental disorders, supports the haploinsufficiency of the DLG2 gene, and suggests a potential association between these deletions and congenital anomalies and dysmorphism.
GENETICS IN MEDICINE
(2024)