Article
Virology
Mudasir Gani, Sergei Senger, Satish Lokanath, Pawan Saini, Kamlesh Bali, Rakesh Gupta, Vankadara Sivaprasad, Johannes A. Jehle, Joerg T. Wennmann
Summary: The study revealed the distribution of Indian BmNPV and investigated their genetic composition through methods like gene sequencing and phylogenetic analysis. It found genetic variations among different isolates and identified some new closely related viral strains.
Article
Zoology
Ryuhei Kokusho, Susumu Katsuma
Summary: The viral protein tyrosine phosphatase (PTP) and viral ecdysteroid UDP-glucosyltransferase (EGT) have been previously thought to contribute to altered host behaviors, but this study found that they may not be essential for certain abnormal behaviors in larvae induced by Bombyx mori nucleopolyhedrovirus, suggesting an unknown core mechanism of baculovirus-induced alteration of host behaviors.
JOURNAL OF INVERTEBRATE PATHOLOGY
(2021)
Article
Biology
Min-Jee Kim, Jeong-Sun Park, Hyeongmin Kim, Seong-Ryul Kim, Seong-Wan Kim, Kee-Young Kim, Woori Kwak, Iksoo Kim
Summary: This research reports the mitochondrial genome sequences of 37 Bombyx mori strains and four B. mandarina individuals in South Korea, obtained by whole-genome sequencing and Sanger sequencing, respectively. The study reveals a significant genetic reduction in B. mori strains compared to B. mandarina, with the highest diversity found in Chinese B. mori. Chinese B. mandarina can be divided into northern and southern groups, and the northern group is suggested to be the immediate progenitor of monophyletic B. mori strains. Surprisingly, the enigmatic South Korean population of B. mandarina is closer genetically to the northern Chinese group, indicating substantial gene flow between the two regions.
Article
Plant Sciences
Jung Min Kim, Ji Su Seo, Jeong Woo Lee, Jae Il Lyu, Jaihyunk Ryu, Seok Hyun Eom, Bo-Keun Ha, Soon-Jae Kwon
Summary: This study aimed to identify quantitative trait loci (QTLs) associated with soybean isoflavone contents. A mutant-based F-2 population was created and a linkage map was constructed. Thirteen QTLs related to agronomic traits and 29 QTLs associated with isoflavone contents were identified. The major QTL associated with isoflavone contents was located on chromosome 11, and four beta-glucosidase genes were identified as potential candidates involved in high isoflavone contents.
Article
Biotechnology & Applied Microbiology
Nicholas P. Howard, Michela Troggio, Charles-Eric Durel, Helene Muranty, Caroline Denance, Luca Bianco, John Tillman, Eric van de Weg
Summary: This study assessed the concordance and accuracy of Illumina Infinium and Affymetrix Axiom SNP array data in apple genomes. The majority of the data was found to be compatible, although intense data filtering and curation were required for data integration. This in-depth analysis may provide valuable insights for future work on SNP array data integration and interpretation, as well as for probe/platform development.
Article
Plant Sciences
Eun Su Lee, Do-Sun Kim, Sang Gyu Kim, Yun-Chan Huh, Chang-Gi Back, Ye-Rin Lee, Muhammad Irfan Siddique, Koeun Han, Hye-Eun Lee, Jundae Lee
Summary: Watermelon is an economically important fruit crop, and gummy stem blight is a major disease encountered during cultivation. Three QTLs associated with gummy stem blight resistance were identified, with two major QTLs identified on chromosome 8 explaining significant phenotypic variations. High-throughput markers were developed for selecting resistant QTLs, and potential candidate genes associated with resistance were predicted.
Article
Biochemistry & Molecular Biology
Maria Radanova, Mariya Levkova, Galya Mihaylova, Rostislav Manev, Margarita Maneva, Rossen Hadgiev, Nikolay Conev, Ivan Donev
Summary: There is a growing interest in studying single nucleotide polymorphisms (SNPs) in microRNA (miRNA) genes, as they may be associated with susceptibility, prognosis, and treatment response in colorectal cancer (CRC). These miRNA-SNPs could serve as non-invasive biomarkers for early detection of CRC. However, contradictory findings have been reported when different research groups investigated the same SNP in a gene for a specific miRNA, highlighting the need for more case-control studies involving participants from different ethnic backgrounds. According to our review, three miRNA-SNPs - miR-146a rs2910164, miR-27a rs895819, and miR-608 rs4919510 - appear to be promising prognostic, diagnostic, and predictive biomarkers for CRC.
Article
Plant Sciences
Gabrielle Sousa Mafra, Janeo Eustaquio de Almeida Filho, Antonio Teixeira do Amaral Junior, Carlos Maldonado, Samuel Henrique Kamphorst, Valter Jario de Lima, Divino Rosa dos Santos Junior, Jhean Torres Leite, Pedro Henrique Araujo Diniz Santos, Talles de Oliveira Santos, Rosimeire Barboza Bispo, Ueliton Alves de Oliveira, Vitor Batista Pinto, Alexandre Pio Viana, Caio Cezar Guedes Correa, Sunny Ahmar, Freddy Mora-Poblete
Summary: The study applied the method of regional heritability mapping (RHM) in a popcorn breeding population to identify QTLs and candidate genes for various traits, revealing associations with forty-six candidate genes within the significant genomic regions. The results obtained by the RHM method have the potential to contribute to knowledge on the genetic architecture of growth and yield traits in popcorn.
Article
Biotechnology & Applied Microbiology
Seema Yadav, Elizabeth M. Ross, Karen S. Aitken, Lee T. Hickey, Owen Powell, Xianming Wei, Kai P. Voss-Fels, Ben J. Hayes
Summary: A LD-based algorithm is proposed to allocate unassigned SNPs to chromosome regions from sparse genetic maps, with an average proportion of over 94% SNP accuracy in placing them to chromosomes in sugarcane, wheat, and barley. This approach can improve genome-wide association studies and genomic prediction in crop species with fragmented and incomplete genome assemblies, benefiting genomic-assisted breeding for orphan crops.
Article
Agriculture, Dairy & Animal Science
Peng Wang, Wentao Li, Ziyi Liu, Xiaoyun He, Rong Lan, Yufang Liu, Mingxing Chu
Summary: This study analyzed the association between PPP2R5C and SLC39A5 gene polymorphisms and litter size in Yunshang black goats. The results showed that the polymorphisms PPP2R5C g.65977743C>T and SLC39A5 g.50676693T>C were significantly associated with the litter size of the third parity in Yunshang black goats. Further experiments confirmed that individuals with CC genotype of PPP2R5C and TT genotype of SLC39A5 had higher expression of these genes in goat ovarian tissues. These findings provide new insights into candidate gene selection for marker-assisted selection in goats.
Article
Agronomy
Mohammad Wali Salari, Patrick Obia Ongom, Rima Thapa, Henry T. Nguyen, Tri D. Vuong, Katy Martin Rainey
Summary: This study investigated the genetic control of sucrose, raffinose, and stachyose in soybeans, identifying several quantitative trait loci (QTLs) on chromosomes 1, 3, and 6. These QTLs explain variance in the levels of these carbohydrates, with potential candidate genes involved in seed development and plant growth.
Article
Cell Biology
Giuseppe Silvestri, Carla Canedo-Ribeiro, Maria Serrano-Albal, Remi Labrecque, Patrick Blondin, Steven G. Larmer, Gabriele Marras, Desmond A. R. Tutt, Alan H. Handyside, Marta Farre, Kevin D. Sinclair, Darren K. Griffin
Summary: The study demonstrated that screening for aneuploid embryos using PGT-A can significantly improve pregnancy and live birth rates in cattle IVP programs. Analyzing 1713 cattle embryos revealed that aneuploid embryos have lower chances of establishing pregnancies and giving rise to live births compared to euploid embryos.
Article
Biochemistry & Molecular Biology
Hui-Jeong An, Sung-Hwan Cho, Han-Sung Park, Ji-Hyang Kim, Young-Ran Kim, Woo-Sik Lee, Jung-Ryeol Lee, Seong-Soo Joo, Eun-Hee Ahn, Nam-Keun Kim
Summary: This study investigated the genetic association between recurrent pregnancy loss (RPL) and microRNA (miRNA) polymorphisms in miR-10aA>T, miR-30cA>G, miR-181aT>C, and miR-499bA>G in Korean women. The study identified specific genotypes of miR-10a and miR-499 that are associated with increased RPL risk.
Article
Nutrition & Dietetics
Yu-Min Huang, Weu Wang, Po-Pin Hsieh, Hsin-Hung Chen
Summary: The genetic effect of obesity plays a significant role in the development of an obesogenic environment. Genes rs712221 and rs2016520 are associated with obesity and show a synergistic effect, increasing the risk of obesity.
Article
Plant Sciences
Xi-ou Xiao, Ning Zhang, Hui Jin, Huaijun Si
Summary: This study evaluated the genetic diversity and population structure of 135 autotetraploid potatoes using SLAF-seq methods. Analysis of 3,397,137 high-quality SNPs revealed that the classification of these potatoes based on SNP profiles did not correlate with their geographical origins. Furthermore, 71 PARMS-SNP markers were successfully used to analyze 190 autotetraploid potato varieties. Overall, these novel SNP markers provide a solid foundation for potato genetic diversity analysis, DUS testing, and plant variety protection.
Article
Entomology
Hiroki Takai, Kiyoshi Asaoka, Fumiko Ishizuna, Takashi Kiuchi, Susumu Katsuma, Toru Shimada
ARTHROPOD STRUCTURE & DEVELOPMENT
(2018)
Article
Biochemistry & Molecular Biology
Haokun Zhang, Takashi Kiuchi, Chikara Hirayama, Susumu Katsuma, Toru Shimada
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2018)
Article
Virology
Hiroyuki Hikida, Ryuhei Kokusho, Jun Kobayashi, Toru Shimada, Susumu Katsuma
Article
Multidisciplinary Sciences
Katsuhiko Ito, Kurako Kidokoro, Susumu Katsuma, Hideki Sezutsu, Keiro Uchino, Isao Kobayashi, Toshiki Tamura, Kimiko Yamamoto, Kazuei Mita, Toru Shimada, Keiko Kadono-Okuda
SCIENTIFIC REPORTS
(2018)
Article
Biochemistry & Molecular Biology
Takahiro Fukui, Takashi Kiuchi, Keisuke Shoji, Munetaka Kawamoto, Toru Shimada, Susumu Katsuma
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2018)
Article
Genetics & Heredity
Haokun Zhang, Takashi Kiuchi, Chikara Hirayama, Yutaka Banno, Susumu Katsuma, Toru Shimada
Article
Multidisciplinary Sciences
Jung Lee, Takashi Kiuchi, Munetaka Kawamoto, Toru Shimada, Susumu Katsuma
Article
Multidisciplinary Sciences
Hiroki Takai, Rika Ozawa, Junji Takabayashi, Saki Fujii, Kiriko Arai, Ryoko T. Ichiki, Takao Koeduka, Hideo Dohra, Toshiyuki Ohnishi, Sakura Taketazu, Jun Kobayashi, Yooichi Kainoh, Satoshi Nakamura, Takeshi Fujii, Yukio Ishikawa, Takashi Kiuchi, Susumu Katsuma, Masayoshi Uefune, Toru Shimada, Kenji Matsui
SCIENTIFIC REPORTS
(2018)
Article
Biochemistry & Molecular Biology
Takashi Kiuchi, Yudai Sugano, Toru Shimada, Susumu Katsuma
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2019)
Article
Entomology
Lingyan Wang, Zhaoming Dong, Juan Wang, Yaru Yin, Huawei Liu, Wenbo Hu, Zhangchuan Peng, Chun Liu, Muwang Li, Yutaka Banno, Toru Shimada, Qingyou Xia, Ping Zhao
JOURNAL OF INSECT SCIENCE
(2018)
Article
Biochemistry & Molecular Biology
Munetaka Kawamoto, Akiya Jouraku, Atsushi Toyoda, Kakeru Yokoi, Yohei Minakuchi, Susumu Katsuma, Asao Fujiyama, Takashi Kiuchi, Kimiko Yamamoto, Toru Shimada
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Yanyan Zhou, Xiaotong Li, Susumu Katsuma, Yusong Xu, Liangen Shi, Toru Shimada, Huabing Wang
Article
Biochemistry & Molecular Biology
Jung Lee, Tomoaki Nishiyama, Shuji Shigenobu, Katsushi Yamaguchi, Yutaka Suzuki, Toru Shimada, Susumu Katsuma, Takashi Kiuchi
Summary: Samia ricini, a giant saturniid moth, has the potential to be a novel lepidopteran model species with stronger disease resistance and richer genetic resources compared to the current model species Bombyx mori. This species can be used for genetic research and forward genetic analyses, targeting specific physiological traits such as food preference, integument color, and larval spot pattern. Additionally, whole genome sequencing of S. ricini revealed its genetic similarities and differences with B. mori, as well as the expansion of certain genes in the S. ricini lineage. Causal genes for cocoon phenotypes have also been mapped, laying the groundwork for further genetic analyses.
MOLECULAR ECOLOGY RESOURCES
(2021)
Article
Biochemistry & Molecular Biology
Xiangping Dai, Takashi Kiuchi, Yanyan Zhou, Shunze Jia, Yusong Xu, Susumu Katsuma, Toru Shimada, Huabing Wang
Summary: The study conducted a comprehensive analysis of the evolution of insect beta-fructofuranosidase transferred through HGT, identifying posttransfer duplications in Lepidoptera and mutations affecting physiological function in Bombyx mori. These findings indicate that gene transfer enhances the digestive and metabolic adaptation of lepidopteran insects.
MOLECULAR BIOLOGY AND EVOLUTION
(2021)
Article
Biochemistry & Molecular Biology
Kenta Tomihara, Saori Tanaka, Susumu Katsuma, Toru Shimada, Jun Kobayashi, Takashi Kiuchi
Summary: In this study, two embryonic lethal mutations, l-t04 and l-m04, were discovered in semiconsomic strains T04 and M04. The mutations responsible for these lethalities were identified as the Bombyx homolog of imaginal discs arrested (Bmida) and TATA box binding protein-associated factor 5 (BmTaf5) through positional cloning and CRISPR/Cas9 mediated knockout screening. These genes were found to play important roles in late embryogenesis of B. mori.
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2023)