Article
Medicine, General & Internal
Vladimir Radlovic, Zoran Golubovic, Zoran Lekovic, Sinisa Ducic, Nedeljko Radlovic, Branislav Jovanovic, Bojan Bukva, Polina Pavicevic, Dejan Nikolic, Jovana Jankovic
Summary: The aim of this study was to determine the importance of Gilbert syndrome (GS) as a risk factor in the development of cholelithiasis in children. The results showed that GS was present in one-sixth of children with cholelithiasis, but it was not the only risk factor for developing this disease.
SRPSKI ARHIV ZA CELOKUPNO LEKARSTVO
(2023)
Article
Gastroenterology & Hepatology
Marcin Krawczyk, Olga Niewiadomska, Irena Jankowska, Krzysztof Jankowski, Sebastian Wieckowski, Dariusz Lebensztejn, Sabina Wiecek, Jolanta Gozdowska, Zbigniew Kulaga, Susanne N. Weber, Dieter Lutjohann, Frank Lammert, Piotr Socha
Summary: This study found that the ABCG8 p.D19H and NPC1L1 rs217434 variants increase the risk of early-onset gallstone formation in children. These results suggest a common lithogenic pathway between children and adults.
LIVER INTERNATIONAL
(2022)
Article
Public, Environmental & Occupational Health
Feng Jia, Yu Ma, Yahui Liu
Summary: This study aimed to assess the association between milk consumption and the incidence of cholelithiasis. It found that frequent milk intake in females and daily milk intake in males were associated with reduced cholelithiasis risk.
Article
Geriatrics & Gerontology
Tung Ching Ho, Yu-Ching Chen, Che-Chen Lin, Hsu-Chih Tai, Cheng-Yu Wei, Yung-Hsiang Yeh, Chung Y. Hsu
Summary: This study revealed that patients with gallstone disease are more likely to develop atrial fibrillation, and that the risk of atrial fibrillation decreases after cholecystectomy. Cardiovascular checkups may be necessary for patients with gallstone disease, especially those who are young and have other typical risk factors.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Medicine, General & Internal
Syed Muhammad Ishaque, Muhammad Sadiq Achackzai, Zia Ud Din, Shahid Pervez
Summary: This study aimed to determine the frequency of esophageal malignancy in Balochistan and evaluate its correlation with predisposing and dietary factors. The results showed that esophageal cancer was mainly associated with high-risk factors such as intake of spicy/salted food, hot beverages, drugs, quid, and tobacco smoking, as well as low intake of fruits and vegetables, lack of awareness, and low socioeconomic status.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2022)
Article
Nutrition & Dietetics
Xuejin Gao, Li Zhang, Siwen Wang, Yaqin Xiao, Deshuai Song, Da Zhou, Xinying Wang
Summary: This study found a high incidence of cholelithiasis in adult patients with SBS, with remnant jejunum and parenteral nutrition dependence as independent risk factors. A proportion of patients in the cholelithiasis group developed acute cholecystitis or cholangitis, as well as acute pancreatitis. Due to the adverse clinical consequences, close monitoring and preventive interventions are recommended for adult patients with SBS.
FRONTIERS IN NUTRITION
(2021)
Article
Psychology, Multidisciplinary
Leonarda Prela, Miquel Llompart, Ewa Dabrowska
Summary: There is great variability in second language (L2) attainment among individuals, and language aptitude plays a significant role in this variability. This study aims to examine the effects of input and aptitude on both native language (L1) and L2 grammatical proficiency. The results show that language aptitude has robust effects on both L1 and L2, with a stronger effect on L1. Additionally, the amount of input has a larger impact on L2 than on L1.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Nutrition & Dietetics
Min Joo Seon, So Yoon Hwang, Yujeong Son, Juhyun Song, Oh Yoen Kim
Summary: Circulating GLP-1 levels may serve as a potential early indicator of MetS risk in women without diagnosed diseases. The levels of GLP-1 positively correlated with adiposity, HOMA-IR, blood pressure, and hs-CRP, and increased proportionally with the number of MetS risk factors.
Article
Nutrition & Dietetics
Calliope Karastogiannidou, Parthena Giannoulaki, Ioannis Samaras, Evangelia Kotzakioulafi, Triantafyllos Didangelos, Ioana Corina Bocsan, Emilia Vassilopoulou
Summary: This study validated the factor structure of the Greek version of DEPS-R, finding it to be reliable in T1DM patients and positively associated with BMI, HbA1c, total daily dose, and time in range. Model comparison supported the use of a single-factor model for efficient screening of disordered eating in Greek T1DM patients.
Article
Cardiac & Cardiovascular Systems
Seo-Young Lee, So-Ryoung Lee, Eue-Keun Choi, Soonil Kwon, Seokhun Yang, Jiesuck Park, You-jung Choi, Hyun-Jung Lee, Inki Moon, Euijae Lee, Kyung-Do Han, Myung-Jin Cha, Seil Oh, Gregory Y. H. Lip
Summary: The study indicates that dynamic changes in metabolic syndrome and persistent metabolic syndrome are associated with an increased risk of atrial fibrillation in a large-scale Asian population. The risk was more strongly correlated with changes in metabolic syndrome status in the young and middle-age groups (aged 20-39 years and 40-64 years, respectively) than in the elderly group (aged 65 years and over).
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Review
Substance Abuse
Youssef Allami, David C. Hodgins, Matthew Young, Natacha Brunelle, Shawn Currie, Magali Dufour, Marie-Claire Flores-Pajot, Louise Nadeau
Summary: A meta-analysis of 104 studies on gambling prevalence found that risk factors associated with continuous-play format gambling products have the highest effect sizes, while those associated with socio-demographic factors have the lowest effects.
Article
Biochemistry & Molecular Biology
Alena Jiraskova, Jan Skrha, Libor Vitek
Summary: This study assessed serum bilirubin concentrations and microsatellite variations in UGT1A1 and HMOX1 genes in patients with type 2 diabetes mellitus (T2DM). Results showed that T2DM patients had lower serum bilirubin concentrations compared to controls, and the prevalence of phenotypic Gilbert syndrome and (TA)(7/7) UGT1A1 genotype was lower in male T2DM patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Oncology
Joo-Hyun Park, Jung Y. Hong, Young S. Park, Gunseog Kang, Kyungdo Han, Joon O. Park
Summary: The study found that persistent metabolic syndrome (MetS) is associated with an increased risk of cholangiocarcinoma (CCA) if it persists for more than 2 years. Even after adjusting for multiple covariates, MetS-persistent status significantly increases the risk of CCA, while improved or newly developed MetS is not associated with CCA risk.
EUROPEAN JOURNAL OF CANCER
(2021)
Article
Medicine, General & Internal
Hong-Yu Shi, Meng-Shi Xie, Chen-Xi Yang, Ri-Tai Huang, Song Xue, Xing-Yuan Liu, Ying-Jia Xu, Yi-Qing Yang
Summary: Congenital heart disease (CHD) is the most common birth deformity and a leading cause of neonatal mortality worldwide. Although some genes have been found to be involved in the pathogenesis of CHD, the genetic components predisposing to CHD in most cases remain unclear. This study identified a new variation in the SOX18 gene associated with CHD and found that it lost transactivation and synergistic activation with other genes responsible for CHD.
Article
Multidisciplinary Sciences
Kazuya Higashizono, Eiji Nakatani, Philip Hawke, Shuhei Fujimoto, Noriyuki Oba
Summary: This study utilized a large population-based cohort to explore risk factors for gallstone formation. The results revealed that male sex, cerebrovascular disease, any malignancy, dementia, rheumatic disease, chronic pulmonary disease, hypertension, and H. pylori-infected gastritis were associated with an increased risk of gallstones.
Article
Biochemistry & Molecular Biology
Theodoros Rampias, Dimitris Karagiannis, Margaritis Avgeris, Alexander Polyzos, Antonis Kokkalis, Zoi Kanaki, Evgenia Kousidou, Maria Tzetis, Emmanouil Kanavakis, Konstantinos Stravodimos, Kalliopi N. Manola, Gabriel E. Pantelias, Andreas Scorilas, Apostolos Klinakis
Article
Clinical Neurology
Konstantina Kosma, Anastasios Mitrakos, Christalena Sofokleous, George Papadimas, Helena Fryssira, Sofia Kitsiou-Tzeli, Maria Tzetis
Article
Hematology
Sfougataki Irene, Grafakos Ioannis, Varela Ioanna, Mitrakos Anastasios, Karagiannidou Angeliki, Tzannoudaki Marianna, Poulou Myrto, Mertzanian Anny, Roubelakis G. Maria, Stefanaki Kalliope, Traeger-Synodinos Joanne, Kanavakis Emmanuel, Kitra Vasiliki, Tzetis Maria, Goussetis Evgenios
BLOOD CELLS MOLECULES AND DISEASES
(2019)
Article
Cell Biology
Argyro Kagia, Maria Tzetis, Emmanuel Kanavakis, Despina Perrea, Irene Sfougataki, Anny Mertzanian, Ioanna Varela, Aikaterini Dimopoulou, Angeliki Karagiannidou, Evgenios Goussetis
Review
Andrology
Panagiotis Ntostis, Georgia Kokkali, David Iles, John Huntriss, Maria Tzetis, Helen Picton, Konstantinos Pantos, David Miller
SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE
(2019)
Article
Oncology
Anastasios Mitrakos, Antonis Kattamis, Katerina Katsibardi, Stefanos Papadhimitriou, Sophia Kitsiou-Tzeli, Emmanuel Kanavakis, Maria Tzetis
Article
Medicine, General & Internal
Eleftheria Kokkinou, Kleoniki Roka, Alexis Alexopoulos, Efthymia Tsina, Ioannis Nikas, Panagiotis Krallis, Ioanna Thanopoulou, Lambrini Nasi, Evanthia Makrygianni, Eirini Tsoutsou, Konstantina Kosma, Maria Tsipi, Maria Tzetis, Helen Frysira, Antonis Kattamis, Roser Pons
POSTGRADUATE MEDICINE
(2019)
Article
Clinical Neurology
Evangelia Tzeravini, Stamatia Samara, Anna Kouramba, Georgios Vakrinos, Athina Efthimiou, Maria Tzetis, Theodoros Androutsakos
Summary: Severe hemophilia A and moyamoya (SHAM) syndrome is a rare condition characterized by the combination of hemophilia A and moyamoya disease. This study reports the case of a 19-year-old male patient with hemophilia A and hypogonadism, presenting with right-sided hemiparesis and dysarthria. Imaging results showed features of moyamoya disease. Genetic sequencing confirmed the presence of a large Xq28 deletion associated with SHAM syndrome. Therefore, the diagnosis of moyamoya disease should be considered in young male patients with unexplained ischemic stroke symptoms, especially in those with known hemophilia.
CASE REPORTS IN NEUROLOGY
(2022)
Article
Genetics & Heredity
Konstantina Kosma, Konstantinos Varvagiannis, Anastasios Mitrakos, Maria Tsipi, Joanne Traeger-Synodinos, Maria Tzetis
Summary: Pathogenic variants in KMT2E cause O'Donnell-Luria-Rodan syndrome, a neurodevelopmental disorder characterized by developmental delay, intellectual disability, and facial dysmorphism. Deletions involving KMT2E also affect other genes, leading to complex phenotypes. The study presented a case of a male with antenatal onset hydronephrosis, hypotonia, and global developmental delay, confirming core features of the disorder while expanding the phenotypic spectrum.
MOLECULAR SYNDROMOLOGY
(2021)
Article
Genetics & Heredity
Anastasios Mitrakos, Leandros Lazaros, Amelia Pantou, Ariadni Mavrou, Emmanuel Kanavakis, Maria Tzetis
MOLECULAR SYNDROMOLOGY
(2020)
Meeting Abstract
Biochemistry & Molecular Biology
M. Tzetis, S. Koutsias, E. Mourmoura, A. Mitrakos, I. Fylaktou, I. Papathanasiou, M. Tsipi, M. Poulou, K. Kosma, A. Giannoukas, A. Tsezou
EUROPEAN JOURNAL OF HUMAN GENETICS
(2019)
Meeting Abstract
Biochemistry & Molecular Biology
M. Poulou, H. Fryssira, S. Kitsiou-Tzeli, M. Tzetis
EUROPEAN JOURNAL OF HUMAN GENETICS
(2019)
Meeting Abstract
Biochemistry & Molecular Biology
I. Papathanasiou, E. Mourmoura, M. Tzetis, A. Tsezou
EUROPEAN JOURNAL OF HUMAN GENETICS
(2019)
Meeting Abstract
Biochemistry & Molecular Biology
K. Kosma, A. K. Mitrakos, M. Poulou, M. Tzetis
EUROPEAN JOURNAL OF HUMAN GENETICS
(2019)
Meeting Abstract
Genetics & Heredity
Nikoletta Selenti, Eirini Tsoutsou, Maria Tzetis, Amenta Stella, Voula Velissariou, Elena Fryssira
MOLECULAR CYTOGENETICS
(2019)