ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

(2011) U Weyemi et al.   ONCOGENE

NADPH oxidase 4 is an oncoprotein localized to mitochondria

(2010) Kelly A. Graham et al.   CANCER BIOLOGY & THERAPY

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

(2010) Joon-Il Jun et al.   NATURE CELL BIOLOGY

NADPH Oxidase 4 Contributes to Transformation Phenotype of Melanoma Cells by Regulating G2-M Cell Cycle Progression

(2009) M. Yamaura et al.   CANCER RESEARCH

NADPH oxidases 1 and 4 mediate cellular senescence induced by resveratrol in human endothelial cells

(2009) Yvonne D.C. Schilder et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive Oxygen Generated by NADPH Oxidase 1 (Nox1) Contributes to Cell Invasion by Regulating Matrix Metalloprotease-9 Production and Cell Migration

(2009) Masahiro Shinohara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Base excision repair of oxidative DNA damage and association with cancer and aging

(2008) S. Maynard et al.   CARCINOGENESIS

Requirement of Reactive Oxygen Species-dependent Activation of ASK1-p38 MAPK Pathway for Extracellular ATP-induced Apoptosis in Macrophage

(2008) Takuya Noguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox-regulation of Erk1/2-directed phosphatase by reactive oxygen species: Role in signaling TPA-induced growth arrest in ML-1 cells

(2008) Kassim Traore et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oncogenic Ras upregulates NADPH oxidase 1 gene expression through MEK-ERK-dependent phosphorylation of GATA-6

(2008) Y Adachi et al.   ONCOGENE

NADPH oxidase 1 plays a critical mediating role in oncogenic Ras-induced vascular endothelial growth factor expression

(2008) D Komatsu et al.   ONCOGENE