The costimulatory molecule CD70 is regulated by distinct molecular mechanisms and is associated with overall survival in diffuse large B-cell lymphoma

The CD70/CD27 Pathway Is Critical for Stimulation of an Effective Cytotoxic T Cell Response against B Cell Precursor Acute Lymphoblastic Leukemia

(2014) L. Glouchkova et al.   JOURNAL OF IMMUNOLOGY

Expression of CD70 in nasal natural killer/T cell lymphoma cell lines and patients; its role for cell proliferation through binding to soluble CD27

(2012) Kazumi Yoshino et al.   BRITISH JOURNAL OF HAEMATOLOGY

CD27 Signaling Increases the Frequency of Regulatory T Cells and Promotes Tumor Growth

(2012) C. Claus et al.   CANCER RESEARCH

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

(2012) J. G. Lohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cells redirected against CD70 for the immunotherapy of CD70-positive malignancies

(2011) D. R. Shaffer et al.   BLOOD

Molecular characterization of 9p21 deletions shows a minimal common deleted region removing CDKN2A exon 1 and CDKN2B exon 2 in diffuse large b-cell lymphomas

(2011) Suzan Guney et al.   GENES CHROMOSOMES & CANCER

Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas

(2011) René Scholtysik et al.   INTERNATIONAL JOURNAL OF CANCER

Opposing Effects of CD70 Costimulation during Acute and Chronic Lymphocytic Choriomeningitis Virus Infection of Mice

(2011) P. Penaloza-MacMaster et al.   JOURNAL OF VIROLOGY

The isotype of the BCR as a surrogate for the GCB and ABC molecular subtypes in diffuse large B-cell lymphoma

(2011) P Ruminy et al.   LEUKEMIA

Interim positron emission tomography scan associated with international prognostic index and germinal center B cell-like signature as prognostic index in diffuse large B-cell lymphoma

(2011) Hélène Lanic et al.   LEUKEMIA & LYMPHOMA

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

(2011) Ryan D. Morin et al.   NATURE

Analysis of the coding genome of diffuse large B-cell lymphoma

(2011) Laura Pasqualucci et al.   NATURE GENETICS

Diffuse large B-cell lymphomas with CDKN2A deletion have a distinct gene expression signature and a poor prognosis under R-CHOP treatment: a GELA study

(2010) F. Jardin et al.   BLOOD

Targeting pancreatic and ovarian carcinomas using the auristatin-based anti-CD70 antibody–drug conjugate SGN-75

(2010) M C Ryan et al.   BRITISH JOURNAL OF CANCER

Genomic lesions associated with a different clinical outcome in diffuse large B-Cell lymphoma treated with R-CHOP-21

(2010) Marta Scandurra et al.   BRITISH JOURNAL OF HAEMATOLOGY

Continuous CD27 triggeringin vivostrongly reduces NK cell numbers

(2010) Veerle De Colvenaer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Epigenetic silencing of TNFSF7 (CD70) by DNA methylation during progression to breast cancer

(2010) Seung Eun Yu et al.   MOLECULES AND CELLS

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

Detection of gene copy number aberrations in mantle cell lymphoma by a single quantitative multiplex PCR assay: clinicopathological relevance and prognosis value

(2009) Fabrice Jardin et al.   BRITISH JOURNAL OF HAEMATOLOGY

Soluble CD70: a novel immunotherapeutic agent for experimental glioblastoma

(2009) James Miller et al.   JOURNAL OF NEUROSURGERY

Recurrent genomic aberrations combined with deletions of various tumour suppressor genes may deregulate the G1/S transition in CD4+CD56+ haematodermic neoplasms and contribute to the aggressiveness of the disease

(2009) F Jardin et al.   LEUKEMIA

Protein Profiling of Plasma Membranes Defines Aberrant Signaling Pathways in Mantle Cell Lymphoma

(2009) Robert S. Boyd et al.   MOLECULAR & CELLULAR PROTEOMICS

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

Identification of candidate tumour suppressor gene loci for Hodgkin and Reed-Sternberg cells by characterisation of homozygous deletions in classical Hodgkin lymphoma cell lines

(2008) Maciej Giefing et al.   BRITISH JOURNAL OF HAEMATOLOGY

Preclinical Characterization of SGN-70, a Humanized Antibody Directed against CD70

(2008) J. A. McEarchern et al.   CLINICAL CANCER RESEARCH

Detection of somatic quantitative genetic alterations by multiplex polymerase chain reaction for the prediction of outcome in diffuse large B-cell lymphomas

(2008) F. Jardin et al.   HAEMATOLOGICA

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

(2008) G. Lenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA