t(4;8)(q27;q24) in Hodgkin lymphoma cells targets phosphodiesterase PDE5A and homeobox gene ZHX2

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

Genome-wide copy number analysis of Hodgkin Reed-Sternberg cells identifies recurrent imbalances with correlations to treatment outcome

(2010) C. Steidl et al.   BLOOD

Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis

(2010) Abdurazzag Abusnina et al.   CELLULAR SIGNALLING

The classical Hodgkin's lymphoma microenvironment and its role in promoting tumour growth and immune escape

(2010) Donatella Aldinucci et al.   JOURNAL OF PATHOLOGY

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)

(2010) Victor Enciso-Mora et al.   NATURE GENETICS

The Tandem Zinc-Finger Region of Human ZHX Adopts a Novel C2H2 Zinc Finger Structure with a C-Terminal Extension

(2009) Hans Wienk et al.   BIOCHEMISTRY

Targeting cancer with phosphodiesterase inhibitors

(2009) Rajkumar Savai et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

STAT6 and STAT1 are essential antagonistic regulators of cell survival in classical Hodgkin lymphoma cell line

(2009) D Baus et al.   LEUKEMIA

Molecular biology of Hodgkin lymphoma

(2009) R. Kuppers   Hematology-American Society of Hematology Education Program

IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis

(2008) F. A. Scheeren et al.   BLOOD

Low expression of ZHX2, but not RCBTB2 or RAN, is associated with poor outcome in multiple myeloma

(2008) A. Armellini et al.   BRITISH JOURNAL OF HAEMATOLOGY

Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma by array-based comparative genomic hybridization

(2008) S. Hartmann et al.   HAEMATOLOGICA