DNMT3B gene amplification predicts resistance to DNA demethylating drugs

Hypomethylating Agents and Other Novel Strategies in Myelodysplastic Syndromes

(2011) Guillermo Garcia-Manero et al.   JOURNAL OF CLINICAL ONCOLOGY

Cancer epigenetics reaches mainstream oncology

(2011) Manuel Rodríguez-Paredes et al.   NATURE MEDICINE

Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy

(2010) Elias Jabbour et al.   CANCER

DNMT3B7, a Truncated DNMT3B Isoform Expressed in Human Tumors, Disrupts Embryonic Development and Accelerates Lymphomagenesis

(2010) M. Y. Shah et al.   CANCER RESEARCH

Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry

(2010) María Berdasco et al.   DEVELOPMENTAL CELL

Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression

(2010) A. E. K. Ibrahim et al.   GUT

Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells

(2010) D. Kuck et al.   MOLECULAR CANCER THERAPEUTICS

DNMT3AMutations in Acute Myeloid Leukemia

(2010) Timothy J. Ley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting DNA methylation for epigenetic therapy

(2010) Xiaojing Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation

(2009) J. Datta et al.   CANCER RESEARCH

Solving the Dnmt2 enigma

(2009) Matthias Schaefer et al.   CHROMOSOMA

DNA Methylation Predicts Survival and Response to Therapy in Patients With Myelodysplastic Syndromes

(2009) Lanlan Shen et al.   JOURNAL OF CLINICAL ONCOLOGY

A Novel DNMT3B Splice Variant Expressed in Tumor and Pluripotent Cells Modulates Genomic DNA Methylation Patterns and Displays Altered DNA Binding

(2009) S. Gopalakrishnan et al.   MOLECULAR CANCER RESEARCH

Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation

(2009) M. Rius et al.   MOLECULAR CANCER THERAPEUTICS

The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA

(2009) Isabel López de Silanes et al.   NUCLEIC ACIDS RESEARCH

An Inactivating Mutation in HDAC2 Leads to Dysregulation of Apoptosis Mediated by APAF1

(2008) Christin L. Hanigan et al.   GASTROENTEROLOGY

Advances in the treatment of acute myeloid leukemia: From chromosomal aberrations to biologically targeted therapy

(2008) Michael Lübbert et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines

(2008) J Devon Roll et al.   Molecular Cancer