LIF in the regulation of T-cell fate and as a potential therapeutic

Retinoic Acid Increases Foxp3+ Regulatory T Cells and Inhibits Development of Th17 Cells by Enhancing TGF- -Driven Smad3 Signaling and Inhibiting IL-6 and IL-23 Receptor Expression

(2014) S. Xiao et al.   JOURNAL OF IMMUNOLOGY

Treg versus Th17 lymphocyte lineages are cross-regulated by LIF versus IL-6

(2011) Wenda Gao et al.   CELL CYCLE

Retinoic acid: A key player in immunity

(2010) Karina Pino-Lagos et al.   BIOFACTORS

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

A LIF/Nanog axis is revealed in T lymphocytes that lack MARCH-7, a RINGv E3 ligase that regulates the LIF-receptor

(2010) Lorraine H. Thompson et al.   CELL CYCLE

Kruppel-like Factor 4 (Klf4) Prevents Embryonic Stem (ES) Cell Differentiation by Regulating Nanog Gene Expression

(2010) Peilin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease

(2010) Ashley D. Reynolds et al.   JOURNAL OF IMMUNOLOGY

CNS-targeted LIF Expression Improves Therapeutic Efficacy and Limits Autoimmune-mediated Demyelination in a Model of Multiple Sclerosis

(2010) Helena Slaets et al.   MOLECULAR THERAPY

Therapeutic potential of LIF in multiple sclerosis

(2010) Helena Slaets et al.   TRENDS IN MOLECULAR MEDICINE

High Weight Differences between Donor and Recipient Affect Early Kidney Graft Function-A Role for Enhanced IL-6 Signaling

(2009) W. Gong et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease

(2009) X. Chen et al.   BLOOD

Cellular structure of the human cerebral cortex

(2009) E. G. Jones   BRAIN

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

Oct4 and LIF/Stat3 Additively Induce Krüppel Factors to Sustain Embryonic Stem Cell Self-Renewal

(2009) John Hall et al.   Cell Stem Cell

The E3 Ligase Axotrophin/MARCH-7: Protein Expression Profiling of Human Tissues Reveals Links to Adult Stem Cells

(2009) Cristina A. Szigyarto et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Site-Specific Production of IL-6 in the Central Nervous System Retargets and Enhances the Inflammatory Response in Experimental Autoimmune Encephalomyelitis

(2009) A. Quintana et al.   JOURNAL OF IMMUNOLOGY

IL-6 Signaling in Psoriasis Prevents Immune Suppression by Regulatory T Cells

(2009) W. A. Goodman et al.   JOURNAL OF IMMUNOLOGY

IL-6 and TNF-  Synergistically Inhibit Allograft Acceptance

(2009) H. Shen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

(2009) Hitoshi Niwa et al.   NATURE

Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

(2009) Markus Feuerer et al.   NATURE IMMUNOLOGY

Capturing Pluripotency

(2008) Jose Silva et al.   CELL

Leukemia inhibitory factor: Role in human mesenchymal stem cells mediated immunosuppression

(2008) Aisha Nasef et al.   CELLULAR IMMUNOLOGY

All-trans Retinoic Acid Inhibits Type 1 Diabetes by T Regulatory (Treg)-Dependent Suppression of Interferon- -Producing T-cells Without Affecting Th17 Cells

(2008) Y.-H. Van et al.   DIABETES

MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse

(2008) Ying Wang et al.   DIFFERENTIATION

Immune markers for Huntington’s disease?

(2008) Edward Wild et al.   Expert Review of Neurotherapeutics

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

Special regulatory T-cell review: FOXP3 biochemistry in regulatory T cells – how diverse signals regulate suppression

(2008) Bin Li et al.   IMMUNOLOGY

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

(2008) Maria Björkqvist et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional immobilization of signaling proteins enables control of stem cell fate

(2008) Kristin Alberti et al.   NATURE METHODS

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

(2008) Satoshi Serada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells

(2008) T. Korn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Naturally Occurring and Adaptive Regulatory T cells Secrete High Levels of Leukaemia Inhibitory Factor upon Activation

(2008) M. Mahic et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Heterokaryon-Based Reprogramming of Human B Lymphocytes for Pluripotency Requires Oct4 but Not Sox2

(2008) Carlos F. Pereira et al.   PLoS Genetics

Regulatory Network Analyses Reveal Genome-Wide Potentiation of LIF Signaling by Glucocorticoids and Define an Innate Cell Defense Response

(2008) David Langlais et al.   PLoS Genetics