Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo

Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides

(2011) Christopher J. Cheng et al.   BIOMATERIALS

Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors

(2011) Jiangbing Zhou et al.   BIOMATERIALS

Targeted Disruption of the CCR5 Gene in Human Hematopoietic Stem Cells Stimulated by Peptide Nucleic Acids

(2011) Erica B. Schleifman et al.   CHEMISTRY & BIOLOGY

Polymer delivery systems for site-specific genome editing

(2011) Nicole Ali McNeer et al.   JOURNAL OF CONTROLLED RELEASE

Targeted Gene Modification of Hematopoietic Progenitor Cells in Mice Following Systemic Administration of a PNA-peptide Conjugate

(2011) Faye A Rogers et al.   MOLECULAR THERAPY

In vivo genome editing restores haemostasis in a mouse model of haemophilia

(2011) Hojun Li et al.   NATURE

Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery

(2011) Jiangbing Zhou et al.   NATURE MATERIALS

TAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells

(2010) A. D. Domashenko et al.   BLOOD

Comparative transfection of DNA into primary and transformed mammalian cells from different lineages

(2010) Rosalie Maurisse et al.   BMC BIOTECHNOLOGY

Nanoparticles Deliver Triplex-forming PNAs for Site-specific Genomic Recombination in CD34+ Human Hematopoietic Progenitors

(2010) Nicole A McNeer et al.   MOLECULAR THERAPY

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

(2010) Nathalia Holt et al.   NATURE BIOTECHNOLOGY

Tissue-specific gene delivery via nanoparticle coating

(2009) Todd J. Harris et al.   BIOMATERIALS

PEGylated PLGA nanoparticles for the improved delivery of doxorubicin

(2009) Jason Park et al.   Nanomedicine-Nanotechnology Biology and Medicine

Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

(2009) Kim A. Woodrow et al.   NATURE MATERIALS

Pro-inflammatory effect of leptin on peripheral blood mononuclear cells of patients with ankylosing spondylitis

(2008) Min-Chan Park et al.   JOINT BONE SPINE

High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine

(2008) Jeremy S. Blum et al.   JOURNAL OF CONTROLLED RELEASE

Repair of DNA lesions associated with triplex-forming oligonucleotides

(2008) Joanna Y. Chin et al.   MOLECULAR CARCINOGENESIS

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

(2008) Elena E Perez et al.   NATURE BIOTECHNOLOGY

Correction of a splice-site mutation in the beta-globin gene stimulated by triplex-forming peptide nucleic acids

(2008) J. Y. Chin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA