Inhibition of TGF-β signaling in genetically engineered tumor antigen-reactive T cells significantly enhances tumor treatment efficacy

Cutting Edge: Antigen-Specific TGF -Induced Regulatory T Cells Suppress Th17-Mediated Autoimmune Disease

(2014) E. N. Huter et al.   JOURNAL OF IMMUNOLOGY

Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF- 1

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy

(2011) S. A. Rosenberg et al.   CLINICAL CANCER RESEARCH

Genetic Engineering of Murine CD8+ and CD4+ T Cells for Preclinical Adoptive Immunotherapy Studies

(2011) Sid P. Kerkar et al.   JOURNAL OF IMMUNOTHERAPY

Oncolytic Adenovirus Expressing Soluble TGFβ Receptor II-Fc-mediated Inhibition of Established Bone Metastases: A Safe and Effective Systemic Therapeutic Approach for Breast Cancer

(2011) Zebin Hu et al.   MOLECULAR THERAPY

TRAF6 inhibits Th17 differentiation and TGF- -mediated suppression of IL-2

(2010) P. J. Cejas et al.   BLOOD

Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts

(2010) S. P. Kerkar et al.   CANCER RESEARCH

Systemic Delivery of an Oncolytic Adenovirus Expressing Soluble Transforming Growth Factor-β Receptor II–Fc Fusion Protein Can Inhibit Breast Cancer Bone Metastasis in a Mouse Model

(2010) Zebin Hu et al.   HUMAN GENE THERAPY

Naive tumor-specific CD4+T cells differentiated in vivo eradicate established melanoma

(2010) Ying Xie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells

(2010) L. Lu et al.   JOURNAL OF IMMUNOLOGY

Synergistic Enhancement of CD8+ T Cell-Mediated Tumor Vaccine Efficacy by an Anti-Transforming Growth Factor-  Monoclonal Antibody

(2009) M. Terabe et al.   CLINICAL CANCER RESEARCH

Adoptive immunotherapy of cancer using CD4+ T cells

(2009) Pawel Muranski et al.   CURRENT OPINION IN IMMUNOLOGY

Tumor-specific Th17-polarized cells eradicate large established melanoma

(2008) P. Muranski et al.   BLOOD

TGFβ secreted by B16 melanoma antagonizes cancer gene immunotherapy bystander effect

(2008) Claudia Penafuerte et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression

(2008) Jennifer A. Wargo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The soluble transforming growth factor-β receptor: Advantages and applications

(2008) Leileata M. Russo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Antitumor Activity of EBV-specific T Lymphocytes Transduced With a Dominant Negative TGF-?? Receptor

(2008) Aaron E. Foster et al.   JOURNAL OF IMMUNOTHERAPY