Minimal doses of a sequence-optimized transgene mediate high-level and long-term EPO expression in vivo: challenging CpG-free gene design

The impact of intragenic CpG content on gene expression

(2010) Asli Petra Bauer et al.   NUCLEIC ACIDS RESEARCH

Nonviral Gene Delivery: Principle, Limitations, and Recent Progress

(2009) Mohammed S. Al-Dosari et al.   AAPS Journal

Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression

(2009) Masaru Mitsui et al.   JOURNAL OF GENE MEDICINE

Therapy of Anemia in Kidney Failure, Using Plasmid Encoding Erythropoietin

(2008) Peggy Richard-Fiardo et al.   HUMAN GENE THERAPY

Rational Vector Design for Efficient Non-viral Gene Delivery: Challenges Facing the Use of Plasmid DNA

(2008) Juergen Mairhofer et al.   MOLECULAR BIOTECHNOLOGY

Advances in High-capacity Extrachromosomal Vector Technology: Episomal Maintenance, Vector Delivery, and Transgene Expression

(2008) Michele MP Lufino et al.   MOLECULAR THERAPY

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression

(2008) Stephen C Hyde et al.   NATURE BIOTECHNOLOGY

Plasmid CpG Depletion Improves Degree and Duration of Tumor Gene Expression After Intravenous Administration of Polyplexes

(2008) Holger K. de Wolf et al.   PHARMACEUTICAL RESEARCH

Effects of Inflammatory Response on In Vivo Transgene Expression by Plasmid DNA in Mice

(2007) Keiko Kako et al.   JOURNAL OF PHARMACEUTICAL SCIENCES