Article
Gastroenterology & Hepatology
Mentore Ribolsi, Edoardo Savarino, Marzio Frazzoni, Michele Cicala
Summary: This study used both conventional and new impedance-pH parameters as predictors of response to label-dose PPI in typical GERD. The mean nocturnal baseline impedance (MNBI) and PSPW index were found to be significantly associated with PPI responsiveness. It was concluded that the novel MII-pH variables together with pathological factors are highly predictive of response to label-dose PPI in typical GERD syndrome.
DIGESTIVE AND LIVER DISEASE
(2023)
Article
Gastroenterology & Hepatology
Asad Jehangir, Zubair Malik, Henry P. Parkman
Summary: This study aimed to examine the correlation between reflux observed on esophagogastric junction (EGJ) during high-resolution esophageal manometry with impedance (HREMI) and reflux on conventional esophageal reflux monitoring studies. The results showed that about 20.5% of patients undergoing HREMI had pathologic reflux at EGJ. Patients with reflux on HREMI more frequently had gastroesophageal reflux disease (GERD) on ambulatory pH monitoring. However, reflux on HREMI had low sensitivity for GERD.
BMC GASTROENTEROLOGY
(2022)
Review
Gastroenterology & Hepatology
Mentore Ribolsi, Matteo Ghisa, Edoardo Savarino
Summary: The article discusses investigations conducted using conventional manometry and high-resolution manometry (HRM) to explore the field of esophageal motility and understand the potential link between motor features and gastroesophageal reflux disease (GERD) pathogenesis. HRM studies have provided insights into the esophageal motor function in patients with various esophageal disorders, as well as the correlation between reduced esophageal motility, disruption of the esophagogastric junction, and gastroesophageal reflux burden.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Dustin A. Carlson, Christina Shehata, Nirmala Gonsalves, Ikuo Hirano, Stephanie Peterson, Jacqueline Prescott, Domenico A. Farina, Jacob M. Schauer, Wenjun Kou, Peter J. Kahrilas, John E. Pandolfino
Summary: This study evaluated the characteristics of secondary peristalsis in patients with EoE and found that abnormal esophageal contractions were associated with disease severity.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Surgery
Jun Liang Teh, Hui Yu Tham, Alex Yu Sen Soh, Corrisa Chee, Guowei Kim, Asim Shabbir, Reuben Kong Min Wong, Jimmy Bok Yan So
Summary: This study focused on reflux after POEM, finding that 43.1% of patients had symptomatic reflux, 60% had endoscopic evidence of esophagitis, and 56% had increased acid exposure on pH-impedance test.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Koichi Muroi, Naomi Kakushima, Kazuhiro Furukawa, Eri Ishikawa, Tsunaki Sawada, Takuya Ishikawa, Keiko Maeda, Takeshi Yamamura, Eizaburo Ohno, Masanao Nakamura, Hiroki Kawashima, Kohei Funasaka, Ryoji Miyahara, Mitsuhiro Fujishiro
Summary: In this study, EoE patients with subjective symptoms were found to have thicker esophageal walls and higher esophageal body pressure. Treatment may reduce esophageal thickness and pressure, leading to improvement of subjective symptoms.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Gastroenterology & Hepatology
Humayra Dervin, Paul Bassett, Rami Sweis
Summary: This study confirms that EGJ-CI is a reliable discriminator between reflux disease and functional heartburn. In patients with borderline reflux, those with a lower EGJ-CI score respond better to anti-reflux therapies.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Mentore Ribolsi, Marzio Frazzoni, Lorenzo Marchetti, Mattia Brigida, Michele Cicala, Edoardo Savarino
Summary: Assessment of proximal esophageal MNBI measurement can increase the diagnostic yield of impedance-pH monitoring. The response to PPI in patients with heartburn is related to mucosal damage in both the distal and proximal esophagus.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Marinde van Lennep, Marin L. Leijdekkers, Jac M. Oors, Marc A. Benninga, Michiel P. van Wijk, Maartje M. J. Singendonk
Summary: Pediatric esophageal function tests are interpretable in more than 90% of cases overall, with differences between age groups. In children under 4 years of age, all patients had imperfections in HRM and 3/8 tests were uninterpretable. HRM in older children and pH-MII+/-mano were interpretable in the vast majority.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2021)
Article
Surgery
Heithem Soliman, Muriel Coupaye, Boris Cohen-Sors, Caroline Gorbatchef, Marie Dior, Nicoleta Nebunu, Sofya Latrache, Maude Le Gall, Andre Bado, Severine Ledoux, Benoit Coffin, Henri Duboc
Summary: In the evolution of GERD symptoms after sleeve gastrectomy, half of the patients showed improvement while one-third developed new symptoms. Predictive factors of postoperative symptoms include preoperative symptoms and positive preoperative ambulatory 24-h esophageal pH monitoring in asymptomatic patients.
Review
Gastroenterology & Hepatology
Mentore Ribolsi, Edoardo Savarino
Summary: Diagnosis and management of GERD remains a challenging area. However, we believe that an accurate upfront evaluation is necessary nowadays to provide patients with GERD with a more accurate diagnosis and the best treatment options.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
(2023)
Article
Physiology
Yi Yang, Jia-Rong Lin, Yan-Qiu Li, Yu-Shan Wei, Zhi-Jun Duan
Summary: The prevalence of obesity is increasing, and it can lead to complications in the digestive system, particularly in the esophagus. This study investigates the impact of varying degrees of obesity on the esophagus, finding that obesity affects the integrity of the esophageal mucosa and causes changes in esophageal motility.
PHYSIOLOGICAL RESEARCH
(2023)
Article
Gastroenterology & Hepatology
Mentore Ribolsi, Michele Pier Luca Guarino, Paola Balestrieri, Annamaria Altomare, Alessandro Tullio, Tommasangelo Petitti, Michele Cicala
Summary: The study demonstrates the utility of upfront esophageal testing in discriminating reflux-related cough patients and predicting PPI response.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Morgan K. Johnson, Manasa Venkatesh, Natalie Liu, Catherine R. Breuer, Amber L. Shada, Jacob A. Greenberg, Anne O. Lidor, Luke M. Funk
Summary: Among 108 patients who underwent anti-reflux surgery, normal preoperative acid exposure time and Toupet fundoplication were significantly associated with improvement in GERD-HRQL. The study suggests that a normal preoperative acid exposure time on pH impedance testing is closely related to improved quality of life after anti-reflux surgery.
JOURNAL OF GASTROINTESTINAL SURGERY
(2021)
Article
Gastroenterology & Hepatology
Andree H. H. Koop, Peter J. J. Kahrilas, Jacob Schauer, John E. E. Pandolfino, Dustin A. A. Carlson
Summary: This study aimed to compare primary peristalsis and contractile reserve on HRM and secondary peristalsis on FLIP Panometry with emptying on TBE for esophageal function assessment. The results showed that primary peristalsis, contractile reserve, and secondary peristalsis were associated with abnormal esophageal retention as measured by TBE. Comprehensive models incorporating primary and secondary peristalsis had better predictive ability.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Review
Surgery
Anne Lejay, Benjamin Colvard, Louis Magnus, Delphine Dion, Yannick Georg, Julie Papillon, Fabien Thaveau, Bernard Geny, Lee Swanstrom, Frederic Heim, Nabil Chakfe
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2018)
Article
Surgery
Filippo Filicori, Christy M. Dunst, Ahmed Sharata, Walaa F. Abdelmoaty, Ahmed M. Zihni, Kevin M. Reavis, Steven R. Demeester, Lee L. Swanstrom
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2019)
Article
Gastroenterology & Hepatology
C. Gonzalez, J. -M. Kwak, F. Davrieux, R. Watanabe, J. Marescaux, L. L. Swanstrom
DISEASES OF THE ESOPHAGUS
(2019)
Article
Surgery
Cristians Gonzalez, Jung-Myun Kwak, Federico Davrieux, Ryohei Watanabe, Jacques Marescaux, Lee Swanstrom
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2019)
Article
Surgery
Walaa F. Abdelmoaty, Christy M. Dunst, Chris Neighorn, Lee L. Swanstrom, Chet W. Hammill
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2019)
Article
Surgery
Ilay Habaz, Silvana Perretta, Allan Okrainec, Oscar M. Crespin, Andrea V. Kwong, Ethan Weiss, Else van der Velden, Ludovica Guerriero, Fabio Longo, Pietro Mascagni, Louis W. C. Liu, Timothy D. Jackson, Lee L. Swanstrom, Eran Shlomovitz
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2019)
Article
Surgery
Barbara Seeliger, Michele Diana, Jelle P. Ruurda, Konstantinos M. Konstantinidis, Jacques Marescaux, Lee L. Swanstrom
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2019)
Article
Surgery
Steve R. Siegal, Christy M. Dunst, Ben Robinson, Elizabeth N. Dewey, Lee L. Swanstrom, Steven R. DeMeester
WORLD JOURNAL OF SURGERY
(2019)
Article
Gastroenterology & Hepatology
Jonathan Cohen, David J. Desilets, Joo Ha Hwang, Kondal R. Kyanam Kabir Baig, Felix W. Leung, Jennifer L. Maranki, Patrick I. Okolo, Lee L. Swanstrom, Amitabh Chak
GASTROINTESTINAL ENDOSCOPY
(2019)
Article
Engineering, Biomedical
Cormac McCarthy, Ian Kanterman, Fabian Trauzettel, H. Alexander Jaeger, Alice-Anne Goetz, Benjamin Colvard, Lee Swanstrom, Padraig Cantillon-Murphy
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2019)
Article
Surgery
Eran Shlomovitz, Neeral R. Patel, Michele Diana, Radu Pescarus, Lee L. Swanstrom
Summary: Gastroduodenal stenting is effective and safe for both benign and malignant foregut diseases. A new technique for immediate gastric repair without the need for a gastrostomy tube in porcine models is feasible.
SURGICAL INNOVATION
(2022)
Review
Health Care Sciences & Services
Michele Manigrasso, Sara Vertaldi, Alessandra Marello, Stavros Athanasios Antoniou, Nader Kamal Francis, Giovanni Domenico De Palma, Marco Milone
Summary: Robot-Assisted Minimally Invasive Esophagectomy is shown to have better outcomes compared to open surgery and conventional laparoscopy, including lower blood loss, infection rates, and higher harvested nodes and R0 resection rates. These findings support the promotion of robotic surgery with further randomized trials to address selection bias.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Surgery
Lee Swanstrom, Silvana Perretta, Margherita Pizzicannella, Maria Rita Rodriguez-Luna, Juan Verde, Alain Garcia, Benoit Gallix
Summary: IHU-Strasbourg conducted various activities during the initial phase of the COVID-19 pandemic, with two out of the three projects still ongoing and one already adopted nationally.
SURGICAL INNOVATION
(2021)
Article
Gastroenterology & Hepatology
Amy Tyberg, Reem Z. Sharaiha, Pietro Familiari, Guido Costamagna, Fernando Casas, Nikhil A. Kumta, Maximilien Barret, Amit P. Desai, Felice Schnoll-Sussman, Payal Saxena, Guadalupe Martinez, Felipe Zamarripa, Monica Gaidhane, Helga Bertani, Peter V. Draganov, Valerio Balassone, Ahmed Sharata, Kevin Reavis, Lee Swanstrom, Martina Invernizzi, Stefan Seewald, Hitomi Minami, Haruhiro Inoue, Michel Kahaleh
DIGESTIVE ENDOSCOPY
(2018)
Review
Gastroenterology & Hepatology
Ezra N. Teitelbaum, Lee L. Swanstrom
LANCET GASTROENTEROLOGY & HEPATOLOGY
(2018)