Article
Multidisciplinary Sciences
Jae-Geum Shim, Eun Kyung Lee, Eun Jung Oh, Eun-Ah Cho, Jiyeon Park, Jun-Ho Lee, Jin Hee Ahn
Summary: This study aimed to develop a novel machine learning model to predict the optimal endotracheal tube depth in pediatric patients. Data from 1436 patients were collected and divided into training and testing datasets. The ML model outperformed formula-based methods, accurately predicting the optimal tube depth and reducing the risk of misplacement.
SCIENTIFIC REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Thomas Schmidt, Nils Reiss, Erk Olbrich, Khaled Chalabi, Thorsten Hagedorn, Kay Tetzlaff
Summary: The outcome of heart transplantation has improved significantly over the past 50 years, allowing many recipients to lead normal lives. This article presents a case study of a heart transplant patient returning to scuba diving, highlighting the potential for post-transplant patients to engage in a wide range of activities. The study evaluated the hemodynamic features and associated risks of scuba diving for heart transplant recipients and concluded that it is possible with proper physical condition and adherence to safety measures.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2023)
Article
Psychology, Clinical
Michael Kaess, Johanna Klar, Jochen Kindler, Peter Parzer, Romuald Brunner, Vladimir Carli, Marco Sarchiapone, Christina W. Hoven, Alan Apter, Judit Balazs, Shira Barzilay, Julio Bobes, Doina Cozman, Vanja Gomboc, Christian Haring, Jean-Pierre Kahn, Helen Keeley, Gergely Meszaros, George J. Musa, Vita Postuvan, Pilar Saiz, Merike Sisask, Peeter Varnik, Franz Resch, Danuta Wasserman
Summary: The study indicates that pathological internet use should be considered as psychopathology, while excessive internet use should be classified as adolescent risk-behavior.
ADDICTIVE BEHAVIORS
(2021)
Article
Medicine, General & Internal
Nicholas R. Munoz, Armin Hojjat, Galvin Dhaliwal, Ajay Adial
Summary: This case report presents a rare complication of knotting in a nasogastric (NG) tube inserted in a 68-year-old patient with AIDS complicated by septic shock. The knotted NG tube was successfully removed with a fiberoptic bronchoscope. Clinicians should be aware of alternative methods, such as using a fiberoptic bronchoscope, for removing knotted NG tubes.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Brooks P. Leitner, Stephan Siebel, Ngozi D. Akingbesote, Xinyi Zhang, Rachel J. Perry
Summary: The intertwined relationship between metabolism and cancer has been recognized for a century. Recent epidemiologic evidence has supported the link between obesity and cancer. This review focuses on the association between obesity, metabolic dysregulation, insulin, and cancer, with an emphasis on investigational metabolic adjuncts to standard-of-care cancer treatment.
BIOCHEMICAL JOURNAL
(2022)
Editorial Material
Nursing
Peijin Esther Monica Fan, Kai Yunn Teo, Min Yi Tan, Shin Yuh Ang
Summary: This case report presents a rare complication of knotting in a nasogastric tube, causing difficulty in its removal. Key takeaway is the importance of emphasizing safe nasogastric tube removal in practitioner training to prevent such complications in the future.
AMERICAN JOURNAL OF NURSING
(2023)
Article
Oncology
Tai Ma, Zhijun Wu, Xiaopeng Zhang, Hui Xu, Ying Feng, Cheng Zhang, Minmin Xie, Yahui Yang, Yi Zhang, Chong Feng, Guoping Sun
Summary: A prognostic scoring model for mortality risk stratification in patients with advanced gastric carcinoma was constructed and validated in two hospital cohorts. The model incorporated multiple survival risk factors and stratified patients based on different risk levels. Results showed the model had good predictive performance in both cohorts.
Article
Geriatrics & Gerontology
Seong-A. Jeong, Jeong Hwan Yook, Moon-Won Yoo, Beom Su Kim, In-Seob Lee, Sehee Kim, Chung Sik Gong, Chang Seok Ko
Summary: This study analyzed the predictors of postoperative complications and risk factors related to long-term survival in elderly patients with gastric cancer. The results indicated that being overweight, the extent of gastrectomy, tumor stage, and overall complications were significant risk factors affecting long-term survival in these patients.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Oncology
Hae-Young Park, Sun Ha Choi, Dohyang Kim, Jinseub Hwang, Yeongkeun Kwon, Jin-Won Kwon
Summary: This study investigated the incidence and risk factors for tuberculosis in gastric cancer patients who had undergone gastrectomy or endoscopic submucosal dissection. The results showed that patients who underwent total gastrectomy had the highest risk of tuberculosis, while patients who underwent endoscopic submucosal dissection also had a significantly increased risk.
Article
Medicine, General & Internal
Kohei Shitara, Florian Lordick, Yung-Jue Bang, Peter Enzinger, David Ilson, Manish A. Shah, Eric Van Cutsem, Rui-Hua Xu, Giuseppe Aprile, Jianming Xu, Joseph Chao, Roberto Pazo-Cid, Yoon-Koo Kang, Jianning Yang, Diarmuid Moran, Pranob Bhattacharya, Ahsan Arozullah, Jung Wook Park, Mok Oh, Jaffer A. Ajani
Summary: Zolbetuximab in combination with mFOLFOX6 significantly prolongs progression-free survival and overall survival in patients with CLDN18.2-positive, HER2-negative, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma, with good safety profile.
Article
Biochemistry & Molecular Biology
Wenting Deng, Lan Jin, Haoran Zhuo, Vasilis Vasiliou, Yawei Zhang
Summary: The study revealed a significant association between alcohol consumption and increased risk of stomach cancer. Heterogeneity in results across different regions and subsites of stomach cancer indicates potential factors such as smoking rates, Helicobacter pylori infection, obesity, and genetic susceptibility. The dose-response analysis showed that higher daily alcohol intake is correlated with a higher risk of stomach cancer.
CHEMICO-BIOLOGICAL INTERACTIONS
(2021)
Article
Multidisciplinary Sciences
Hye Jin Kim, Yunho Roh, Soon Young Yun, Wyun Kon Park, Ha Yan Kim, Min Ho Lee, Hyun Joo Kim
Summary: This study aimed to find predictive factors for nostril size and maximum allowable proximal-cuff-to-tip distance for nasotracheal tubes. It was found that sex and height were significant predictors. Selecting the tube diameter based on sex rather than nostril size led to a larger proportion of patients with appropriate cuff/tip location.
Article
Multidisciplinary Sciences
Chen-Hung Chou, Chia-Ling Tsai, Kai-Lieh Lin, Shao-Chun Wu, Min-Hsien Chiang, Hui-Wen Huang, Kuo-Chuan Hung
Summary: This retrospective study aimed to develop a new formula for selecting the appropriate size and determining the depth of a cuffed nasotracheal intubation (NTI) for pediatric dental surgery patients. The study compared clinical data with age-based formulas to evaluate correlation. The results showed that the actual tube size was smaller and the depth was greater than the age-based formulas, and predictors for size and depth were determined using linear regression analysis.
SCIENTIFIC REPORTS
(2023)
Editorial Material
Hematology
Daniel J. Hampshire
Summary: Among rare bleeding disorders, factor VII deficiency is the most common, but it is challenging to correlate deficiency with bleeding phenotype. In their study, Lou and colleagues investigate a large cohort of unrelated factor VII deficient patients, providing further perspective on the link between genotype and phenotype in this disorder.
BRITISH JOURNAL OF HAEMATOLOGY
(2023)
Article
Thermodynamics
Mahyar Seyd Eshaghi, Mohammad Ameri, Amin Rasam, Mokhtar Bidi
Summary: In this study, numerical simulations are employed to analyze the hydrodynamic and thermal entrance regions of turbulent flow in a circular tube with a tight-fit twisted tape insert and prescribed constant wall temperature. Ethylene glycol, water, and Therminol-LT are considered, with inlet velocities ranging from 0.4 to 1 m/s and three common pitch ratios of 5, 8, and 10. The simulations utilize the RANS equations with the Boussinesq hypothesis and the SST-K-Omega turbulence model. Mean non-dimensional velocity and temperature profiles are assessed to confirm the flow's full development. Distinguishing features of the developing and fully-developed regions are compared using velocity and temperature profiles, contours, and flow streamlines. This analysis provides a novel guideline for assessing flow development in pipe flows with twisted-tape inserts. Correlations for dimensionless hydrodynamic and thermal entrance lengths, as well as Nu and Fanning friction factor, are proposed for the first time, allowing for the estimation of these quantities under a wide range of operating conditions.
THERMAL SCIENCE AND ENGINEERING PROGRESS
(2023)