Article
Gastroenterology & Hepatology
John M. DeWitt, Mohammad A. Al-Haddad, Jeffrey J. Easler, Stuart Sherman, James Slaven, Timothy B. Gardner
Summary: Real-time EUS findings and ePFTs significantly impact the clinical assessment of MCCP. The diagnosis of EPI shows poor correlation with the EUS diagnosis of MCCP.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Calvin Jianyi Koh, Sundeep Lakhtakia, Mitsuhiro Kida, Cosmas Rinaldi A. Lesmana, Tiing Leong Ang, Charles Kieng Fong Vu, Than Than Aye, Sun Hwa Park, Majid A. Almadi, Charing Ching-Ning Chong, Raymond Shing Yan Tang, Xi Wu, Ida Hilmi, Vinay Dhir, Nonthalee Pausawasdi, Jahangeer Basha, Zhen-Dong Jin, Ai Ming Yang, Anthony Yuen Bun Teoh, Dong-Wan Seo, Hsiu-Po Wang, Khek Yu Ho
Summary: This multicenter Asian study aimed to define and validate the EUS features of chronic pancreatitis, yielding six EUS features with good interobserver agreement. These features showed high accuracy in diagnosing chronic pancreatitis, providing a useful tool for clinical practice and further research in pancreatic cancer surveillance.
Article
Gastroenterology & Hepatology
Neil B. Marya, Patrick D. Powers, Suresh T. Chari, Ferga C. Gleeson, Cadman L. Leggett, Barham K. Abu Dayyeh, Vinay Chandrasekhara, Prasad G. Iyer, Shounak Majumder, Randall K. Pearson, Bret T. Petersen, Elizabeth Rajan, Tarek Sawas, Andrew C. Storm, Santhi S. Vege, Shigao Chen, Zaiyang Long, David M. Hough, Kristin Mara, Michael J. Levy
Summary: The study developed an endoscopic ultrasound-based convolutional neural network model that can differentiate autoimmune pancreatitis from other pancreatic diseases in real time with high accuracy. The use of this model can help in early diagnosis and improve patient outcomes.
Article
Orthopedics
Jian Lin, Wei-Jin Sun, Jian-Hai Chen, Jing-Ming Dong, Ding-Su Bao, Ling Yan, Wei-Dong Ni, Ming Xiang, Jian Ding, Ming Cai, Jia-Xiang Song, Ming-Gui Mao, Xiao-Ming Wu
Summary: This study compared the interobserver agreement of four classification systems for lateral clavicle fractures used by shoulder specialists and general trauma surgeons. The results showed that when 3D-CT scan images were provided, the interobserver agreement was higher in the specialist group using the OTA, Jager/Breitner, and Gongji classification systems, and in the generalist group using the Gongji classification system. Overall, 3D-CT scans provided better results in most classification systems, emphasizing the value of digitization and specialization in diagnosis and treatment.
ORTHOPAEDIC SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Riccardo Mei, Lukas Kessler, Kim M. Pabst, Manuel Weber, Christian Schmidkonz, Christoph Rischpler, Helle Damgaard Zacho, Thomas Hope, Sarah M. Schwarzenbo, Martin Allen-Auerbach, Louise Emmett, Justin Ferdinandus, Marcus Unterrainer, Benedikt M. Schaarschmidt, Lale Umutlu, Andrea Farolfi, Paolo Castellucci, Cristina Nanni, Silvi Telo, Stefano Fanti, Ken Herrmann, Wolfgang P. Fendler
Summary: The interpretation of 68Ga-FAPI PET/CT for cancer imaging showed substantial reproducibility and accuracy among highly experienced observers only, suggesting the importance of training or experience for accurate interpretation and avoiding misdiagnosis of different tumor entities.
JOURNAL OF NUCLEAR MEDICINE
(2023)
Article
Multidisciplinary Sciences
Lisanne van Gennip, Frederike J. C. Haverkamp, Ozcan Sir, Edward C. T. H. Tan
Summary: This study aimed to evaluate the most commonly used classifications for acute wounds in the Netherlands and assess the interobserver variability of the Gustilo Anderson wound classification (GAWC) and Red Cross wound classification (RCWC) in acute wounds. The study found that both classifications had moderate interobserver variability and were helpful for acute wound assessment, although their user-friendliness was moderate. It is recommended to apply the GAWC to acute wounds with fractures and the RCWC to major traumatic injuries.
SCIENTIFIC REPORTS
(2022)
Article
Agriculture, Dairy & Animal Science
Masoud Aghapour, Barbara Bockstahler, Sibylle Kneissl, Aldo Vezzoni, Michaela Gumpenberger, Harald Hechinger, Alexander Tichy, Britta Vidoni
Summary: Hip laxity is a common orthopedic disorder in dogs and a main cause of canine hip dysplasia. Timely measures can be taken to prevent/delay the disease progression and reduce its prevalence. Effective treatment strategies can improve the welfare of dogs by reducing disease severity at older ages.
Article
Cell Biology
Sohaib Abu-Farsakh, Michael G. Drage, Aaron R. Huber, Bradley M. Turner, Sharlin Varghese, Xi Wang, Christa L. Whitney-Miller, Raul S. Gonzalez
Summary: There is a mild to moderate degree of interobserver variability in the diagnosis of anal dysplasia among pathologists. The study indicates the utility of some form of consensus conference, as overall agreement among GI pathologists and among GYN pathologists improved following in-person consensus.
Article
Gastroenterology & Hepatology
Andrew Canakis, Shivanand Bomman, David U. Lee, Andrew Ross, Michael Larsen, Rajesh Krishnamoorthi, Adnan A. Alseidi, Mohamed Abdelgadir Adam, Abdul Kouanda, Reem Z. Sharaiha, SriHari Mahadev, Sanad Dawod, Kartik Sampath, Mustafa A. Arain, Aimen Farooq, Muhammad K. Hasan, Kambiz Kadkhodayan, Sebastian G. de la Fuente, Petros C. Benias, Arvind J. Trindade, Michael Ma, Andrew J. Gilman, Gregory H. Fan, Todd H. Baron, Shayan S. Irani
Summary: This study is the largest comparative study to date between EUS-GE and SGJ for mGOO. The results show that EUS-GE has shorter time to resumption of oral intake, lower albumin levels, and shorter length of stay compared with SGJ. EUS-GE also allows earlier resumption of diet and chemotherapy with fewer adverse events.
GASTROINTESTINAL ENDOSCOPY
(2023)
Review
Ophthalmology
Ashwin Ramanathan, Sam Ebenezer Athikarisamy, Geoffrey C. Lam
Summary: With the increasing survival of premature infants, there is a growing demand for better retinopathy of prematurity (ROP) services. Wide field retinal imaging (WFDRI) and artificial intelligence (AI) have shown promise in improving ROP diagnosis and reducing the workload of screening ophthalmologists. This review systematically summarizes the diagnostic characteristics of existing deep learning algorithms, highlighting their potential in diagnosing ROP and providing an automated severity score. AI techniques have demonstrated comparable accuracy and sensitivity to ophthalmologists. However, more evidence is needed before AI can be used as a sole diagnostic tool.
Article
Multidisciplinary Sciences
Diego Alvarez-Estevez, Roselyne M. Rijsman
Summary: The study introduces a new deep learning method for automatic sleep staging and evaluates its generalization capabilities on various public sleep staging databases. The results demonstrate that using an ensemble approach can improve the model's prediction performance on external datasets.
Review
Pharmacology & Pharmacy
Peter Szatmary, Tassos Grammatikopoulos, Wenhao Cai, Wei Huang, Rajarshi Mukherjee, Chris Halloran, Georg Beyer, Robert Sutton
Summary: Acute pancreatitis is a common disease that requires comprehensive management and may lead to severe complications and death. Patients with local complications should receive specialist management.
Article
Gastroenterology & Hepatology
Pedram Paragomi, Marie Tuft, Ioannis Pothoulakis, Vikesh K. Singh, Tyler Stevens, Haq Nawaz, Jeffrey J. Easler, Shyam Thakkar, Gregory A. Cote, Peter J. Lee, Venkata Akshintala, Ayesha Kamal, Amir Gougol, Anna Evans Phillips, Jorge D. Machicado, David C. Whitcomb, Phil J. Greer, James L. Buxbaum, Phil Hart, Darwin Conwell, Gong Tang, Bechien U. Wu, Georgios Papachristou
Summary: The study validated the Pancreatitis Activity Scoring System (PASS) in a cohort of acute pancreatitis patients and found significant differences in PASS trajectories among different severity levels and lengths of hospital stay groups.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Erick Cruz Grave, Thomas Loehfelm, Michael T. Corwin, Joseph Zepeda, Harjot K. Bath, Sandeep Dhaliwal, Maryam Yazdanfar, Christopher L. Bowlus
Summary: This study found that the Anali score provides additional predictive value for hepatic decompensation in patients with PSC. The Anali score has good discriminative ability with the Mayo risk score and can serve as an independent predictor.
ABDOMINAL RADIOLOGY
(2023)
Article
Critical Care Medicine
Suzanne F. M. Van Wijck, Christian Curran, Angela Sauaia, Esther M. M. Van Lieshout, SarahAnn S. Whitbeck, John G. Edwards, Fredric M. Pieracci, Mathieu M. E. Wijffels
Summary: This study validates the universal nomenclature for rib fractures proposed by the international Chest Wall Injury Society. The classification showed strong agreement for fracture location, moderate agreement for fracture type, but lower agreement for rib fracture displacement.
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2022)
Review
Gastroenterology & Hepatology
Sohini Sameera, Tayyaba Mohammad, Kelvin Liao, Haroon Shahid, Avik Sarkar, Amy Tyberg, Michel Kahaleh
Summary: Managing pancreatic fluid collections (PFCs) remains challenging, but recent developments in technology and minimally invasive endoscopic techniques have improved treatment options. These advancements offer less traumatic alternatives to surgery and more effective options than percutaneous techniques. This review will discuss the latest developments in PFC management and their incorporation into current treatment algorithms.
JOURNAL OF CLINICAL GASTROENTEROLOGY
(2023)
Review
Gastroenterology & Hepatology
Marcella Pimpinelli, Michael Makar, Michel Kahaleh
Summary: Management of hilar strictures is challenging for endoscopists. While various strategies have been demonstrated, there is limited consensus in the literature. This review aims to summarize the current literature and discuss emerging therapies, such as photodynamic therapy and radiofrequency ablation.
DIGESTIVE ENDOSCOPY
(2023)
Article
Surgery
Jesse D. Schold, Anne M. Huml, S. Ali Husain, Emilio D. Poggio, R. Blake Buchalter, Rocio Lopez, Bruce Kaplan, Sumit Mohan
Summary: In the United States, over 20% of procured kidneys for transplantation are not utilized. This study examined the factors associated with nonutilization and found that deceased donors from higher distressed communities were more likely to have their kidneys not utilized. The study also found regional variations in kidney nonutilization rates and minimal impact on recipient outcomes.
AMERICAN JOURNAL OF TRANSPLANTATION
(2023)
Article
Gastroenterology & Hepatology
Carlos Robles-Medranda, Jorge Baquerizo-Burgos, Juan Alcivar-Vasquez, Michel Kahaleh, Isaac Raijman, Rastislav Kunda, Miguel Puga-Tejada, Maria Egas-Izquierdo, Martha Arevalo-Mora, Juan C. Mendez, Amy Tyberg, Avik Sarkar, Haroon Shahid, Raquel del Valle-Zavala, Jorge Rodriguez, Ruxandra C. Merfea, Jonathan Barreto-Perez, Gabriela Saldana-Pazmino, Daniel Calle-Loffredo, Haydee Alvarado, Hannah P. Lukashok
Summary: The study aims to develop a CNN model for detecting neoplastic lesions during real-time DSOC and clinically validate it against expert and nonexpert endoscopists. The results demonstrate that the CNN model achieved high accuracy in diagnosing neoplastic lesions and outperformed both nonexpert and expert endoscopists.
Editorial Material
Gastroenterology & Hepatology
Sardar M. Shah-Khan, Khaled Elfert, Avik Sarkar, Haroon Shahid, Amy Tyberg, Michel Kahaleh
Article
Gastroenterology & Hepatology
Jose Antonio Almario, Linda Zhang, Jonathan A. Cohen, Gregory Haber, Hemchand Ramberan, Andrew Storm, Stuart Gordon, Jeffrey Adler, Heiko Pohl, Alexander Schlachterman, Anand Kumar, Shailendra Singh, Bashar Qumseya, Peter Draganov, Nikhil Kumta, Andrew Canakis, Raymond M. Kim, Hiroyuki Aihara, Apurva Shrigiriwar, Saowanee Ngamruengphong, Mouen N. Khashab
Summary: The use of a novel through-the-scope (TTS) suturing system for the closure of duodenal EMR defects of >= 10mm resulted in a high rate of complete closure and no cases of delayed bleeding events.
Article
Gastroenterology & Hepatology
Linda Y. Zhang, Oscar Hernandez Mondragon, Mathieu Pioche, Steven N. Steinway, Jose Nieto, Michael B. Ujiki, Vanessa N. VanDruff, Raymond E. Kim, Andrew Canakis, Marcel Tantau, Alina Tantau, Anamaria Pop, Jeremie Jacques, Michael Lajin, Pankaj Desai, Apurva Shrigiriwar, Michael Bejjani, Nikhil A. Kumta, Mouen A. Khashab
Summary: Background: Zenker's diverticulum peroral endoscopic myotomy (zPOEM) is a minimally invasive treatment strategy for Zenker's diverticulum. This study evaluated the use of zPOEM in the management of large Zenker's diverticulum. Results: The study demonstrated that zPOEM is a safe and effective treatment for large Zenker's diverticulum.
Editorial Material
Gastroenterology & Hepatology
Monica Saumoy, Arvind J. Trindade, Amit Bhatt, Juan Carlos Bucobo, Vinay Chandrasekhara, Andrew P. Copland, Samuel Han, Allon Kahn, Kumar Krishnan, Nikhil A. Kumta, Ryan Law, Jorge Obando, Mansour A. Parsi, Guru Trikudanathan, Julie Yang, David R. Lichtenstein
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Apostolis Papaefthymiou, Michel Kahaleh, Arnaud Lemmers, Sandro Sferrazza, Maximilien Barret, Katsumi Yamamoto, Pierre Deprez, Jose C. Marin-Gabriel, George Tribonias, Hong Ouyang, Federico Barbaro, Oleksandr Kiosov, Stefan Seewald, Gaurav Patil, Shaimaa Elkholy, Dimitri Coumaros, Clemence Vuckovic, Matthew Banks, Rehan Haidry, Georgios Mavrogenis
Summary: This study evaluated the recurrence rate of undifferentiated early gastric cancer (UD-EGC) after endoscopic submucosal dissection (ESD) and identified potential risk factors. The results showed that 5.6% of patients had local recurrence after ESD, with no lymph node or distant metastases reported. Lesion size was not associated with recurrence, while lymphovascular and perineural invasion were independent risk factors for local recurrence.
ENDOSCOPY INTERNATIONAL OPEN
(2023)
Review
Gastroenterology & Hepatology
Mihajlo Gjeorgjievski, Abishek Bhurwal, Abhishek A. Chouthai, Abdelhai Abdelqader, Monica Gaidhane, Haroon Shahid, Amy Tyberg, Avik Sarkar, Michel Kahaleh
Summary: The study aimed to evaluate the efficacy and safety of percutaneous endoscopic necrosectomy (PEN) in necrotizing pancreatitis. Through the analysis of 16 observational studies, it was found that PEN is a novel method of endoscopic management of pancreatic necrosis, with high rates of clinical success and low rates of perioperative morbidity and mortality.
ENDOSCOPY INTERNATIONAL OPEN
(2023)
Article
Gastroenterology & Hepatology
Rodrigo Duarte-Chavez, Amy Tyberg, Avik Sarkar, Haroon M. Shahid, Bhargav Vemulapalli, Sardar Shah-Khan, Monica Gaidhane, Michel Kahaleh
Summary: This study compared invasive and noninvasive CO2 monitoring methods during peroral endoscopic myotomy (POEM). The results showed a strong correlation between arterial CO2 levels (PaCO2) and end-tidal CO2 levels (etCO2), suggesting that etCO2 monitoring is sufficient in most cases.
ENDOSCOPY INTERNATIONAL OPEN
(2023)
Article
Gastroenterology & Hepatology
Danse Bi, Linda Y. Zhang, Mohammad Alqaisieh, Apurva Shrigiriwar, Jad Farha, Tala Mahmoud, Karl Akiki, Jose Antonio Almario, Sardar M. Shah-Khan, Stuart R. Gordon, Jeffrey M. Adler, Mark Radetic, Peter Draganov, Yakira N. David, Brianna Shinn, Zahraa Mohammed, Alexander Schlachterman, Sofia Yuen, Ahmad Al-Taee, Namn Yunseok, Roberto Trasolini, Michael Bejjani, Bachir Ghandour, Hemchand Ramberan, Andrew Canakis, Saowanee Ngamruengphong, Andrew C. Storm, Shailendra Singh, Heiko Pohl, Juan Carlos Bucobo, Jonathan M. Buscaglia, Lionel S. D'Souza, Bashar Qumseya, Nikhil A. Kumta, Anand Kumar, Gregory B. Haber, Hiroyuki Aihara, Mandeep Sawhney, Raymond Kim, Tyler M. Berzin, Mouen A. Khashab
Summary: Closure of large colon polyp EMR sites with TTSS can effectively reduce the risk of delayed bleeding, with a high success rate of closure. However, 3.2% of cases still experienced delayed bleeding.
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Nicholas A. Hoerter, Michael S. Smith, Rebekah E. Dixon, Zachary Spiera, Monica Saumoy, Prashant Kedia, David P. Lee, Nikhil A. Kumta, Satish Nagula, Christopher J. DiMaio
TECHNIQUES AND INNOVATIONS IN GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Abel Joseph, Michel Kahaleh, Andrew A. Li, Gregory B. Haber, Prashant Kedia, Mai Ego Makiguchi, Neil R. Sharma, Joo Ha Hwang, Amitabh Chak, Ahmad M. Al-Taee, David Braun, Shaffer Mok, Neal A. Mehta, Emre Gorgun, John Vargo, Seiichiro Abe, Yutaka Saito, Tyler Stevens, Amit Bhatt
Summary: This study evaluated the efficacy, safety, and efficiency of a novel retraction device called traction wire (TW) in ESD. The result showed that TW significantly reduced the submucosal dissection time and total procedure time, and it was safely used in clinical practice without adverse events.
TECHNIQUES AND INNOVATIONS IN GASTROINTESTINAL ENDOSCOPY
(2023)