Article
Radiology, Nuclear Medicine & Medical Imaging
Andrea Ponsiglione, Arnaldo Stanzione, Gaia Spadarella, Agah Baran, Luca Alessandro Cappellini, Kevin Groot Lipman, Peter Van Ooijen, Renato Cuocolo
Summary: The overall methodological rigor of radiomics studies in the ovarian field is not ideal, with a lack of prospective design and formal validation of results. This limits the reproducibility of results and potential translation to clinical setting.
EUROPEAN RADIOLOGY
(2023)
Article
Oncology
Michael P. Flood, Joseph C. Kong, Toan Pham, Peadar S. Waters, Mikael Soucisse, Robert Ramsay, Hui-Li Wong, Catherine Mitchell, Michael Michael, Jacob J. McCormick, Satish K. Warrier, Tim Akhurst, Alexander G. Heriot
Summary: The study aimed to assess the ability of preoperative PET in predicting the histological grade of pseudomyxoma peritonei (PMP). The results showed that preoperative PET had a positive correlation with high-grade PMP and acceptable sensitivity and specificity as a diagnostic tool. Therefore, PET should be considered a useful adjunct to predict the histological grade in the staging of PMP patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ieun Yoon, Jae Seok Bae, Jeongin Yoo, Dong Ho Lee, Se Hyung Kim
Summary: Studies suggest that compared to MDCT alone, MDCT combined with [F-18]FDG PET/MRI can improve the diagnostic accuracy for preoperative M staging and resectability in patients with recurrent gastric cancer, with a significant advantage in evaluating M staging.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yun Hye Song, Jung Won Moon, Yoo Na Kim, Ji Young Woo, Hye Joo Son, Suk Hyun Lee
Summary: This study aimed to investigate the reduction of [F-18]FDG uptake in dependent lungs by performing [F-18]FDG PET/CT in the prone position. The results showed that dependent lungs had significantly higher SUVmean and HU compared to nondependent lungs on both supine and prone position PET/CT. The study concluded that prone position PET/CT can effectively reduce gravity-dependent opacity-related [F-18]FDG uptake.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lennart Flygare, Secil Telli Erdogan, Karin Soderkvist
Summary: This study compared the performance of FDG-PET/CT and FDG-PET/MRI in locoregional staging of oropharyngeal carcinomas. The results showed that PET/MRI had slightly higher specificity and accuracy for nodal staging compared to PET/CT. Both methods demonstrated excellent sensitivity and high negative predictive values. The study suggests that PET/MRI may be a viable alternative to PET/CT for TN staging and assessment of maximal tumor diameter in oropharyngeal squamous cell cancer.
Article
Radiology, Nuclear Medicine & Medical Imaging
Francesca Marturano, Priscilla Guglielmo, Andrea Bettinelli, Fabio Zattoni, Giacomo Novara, Alessandra Zorz, Matteo Sepulcri, Michele Gregianin, Marta Paiusco, Laura Evangelista
Summary: Radiomic analysis can assist in predicting biochemical recurrence in intermediate and high-risk prostate cancer patients. Combining clinical data with radiomic features improves the accuracy of prediction.
EUROPEAN RADIOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Seyed Ali Mirshahvalad, Andres Kohan, Ur Metser, Ricarda Hinzpeter, Claudia Ortega, Adam Farag, Patrick Veit-Haibach
Summary: This study conducted a diagnostic meta-analysis to evaluate the performance of [F-18]FDG PET/MR in M staging of [F-18]FDG-avid cancer entities. The results showed that [F-18]FDG PET/MR is highly accurate in detecting distant metastasis and has high sensitivity and specificity in various malignancy types. These findings provide clinicians and patients with confidence in the performance of [F-18]FDG PET/MR in clinical practice.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Kotaro Nomura, Mariko Fukui, Aritoshi Hattori, Takeshi Matsunaga, Kazuya Takamochi, Kenji Suzuki
Summary: Preoperative staging of lymph node metastasis in patients with non-small cell lung cancer and usual interstitial pneumonia is difficult due to false-positive imaging findings and clinical upstaging caused by inflammation. This study showed that the diagnostic performance of PET/CT in patients with interstitial pneumonia was lower than that in patients without interstitial pneumonia, and the accuracy of nodal staging was further decreased in patients with FDG uptake.
ANNALS OF THORACIC SURGERY
(2022)
Article
Medicine, General & Internal
Roelof J. Beukinga, Floris B. Poelmann, Gursah Kats-Ugurlu, Alain R. Viddeleer, Ronald Boellaard, Robbert J. De Haas, John Th M. Plukker, Jan Binne Hulshoff
Summary: This study demonstrates that a radiomic model using baseline F-18-FDG PET can predict non-response to neoadjuvant chemoradiotherapy in esophageal cancer patients, providing a potential clinical benefit.
Article
Medicine, General & Internal
Chung Won Lee, Hye Joo Son, Ji Young Woo, Suk Hyun Lee
Summary: Prone position PET/CT is not always useful in evaluating hepatic lesions, but it may be helpful in individual cases such as hepatic dome lesions. There is no significant difference in SUVmax and MTV between supine position PET/CT and prone position PET/CT.
Article
Urology & Nephrology
Sarah R. Ottenhof, Rosa S. Djajadiningrat, Michelle W. J. Versleijen, Maarten L. Donswijk, Vincent van der Noort, Oscar R. Brouwer, Niels M. Graafland, Erik Vegt, Simon Horenblas
Summary: FDG-PET/CT has high diagnostic value for staging pelvic lymph nodes and detecting distant metastases in high-risk penile cancer patients. It has high sensitivity and negative predictive value for pelvic lymph node staging, as well as a high positive predictive value for the detection of distant metastases.
EUROPEAN UROLOGY FOCUS
(2022)
Article
Surgery
Rebecca A. Carr, Meier Hsu, Caitlin A. Harrington, Kay See Tan, Manjit S. Bains, Matthew J. Bott, David H. Ilson, James M. Isbell, Yelena Y. Janjigian, Steven B. Maron, Bernard J. Park, Valerie W. Rusch, Smita Sihag, Abraham J. Wu, David R. Jones, Geoffrey Y. Ku, Daniela Molena
Summary: This study compared the efficacy and safety of induction FOLFOX followed by PET-directed nCRT, induction CP followed by PET-directed nCRT, and nCRT with CP alone. The results showed that induction FOLFOX group had higher rates of pCR, near-pCR and 2-year DFS, suggesting that induction FOLFOX followed by PET-directed nCRT may be more effective than the other two methods.
Article
Clinical Neurology
J. Therriault, S. Gauthier, P. Rosa-Neto
Summary: Biomarkers have revolutionized the study and clinical diagnosis of Alzheimer's disease (AD), with tau pathology closely associated with neurodegeneration and clinical dysfunction. This makes tau-PET a useful tool for determining the severity of AD and monitoring its progression.
JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Robert Burns, Sebastien Mule, Paul Blanc-Durand, Mojdeh Tofighi, Karim Belhadj, Pierre Zerbib, Fabien Le Bras, Laurence Baranes, Corinne Haioun, Emmanuel Itti, Alain Luciani
Summary: The WB-PET/MRI dataset, including T1 and T2 Dixon, WB-DWI, and PET images, provides the optimal diagnostic performance for detecting both focal lesions and diffuse bone marrow involvement. WB-PET/MRI and WB-DCE-PET/MRI show superior sensitivity for focal bone marrow involvement compared to PET alone, while WB-MRI performs best for detecting diffuse bone marrow involvement.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nils Martin Bruckmann, Julian Kirchner, Lale Umutlu, Wolfgang Peter Fendler, Robert Seifert, Ken Herrmann, Ann-Kathrin Bittner, Oliver Hoffmann, Svjetlana Mohrmann, Christina Antke, Lars Schimmoeller, Marc Ingenwerth, Katharina Breuckmann, Andreas Stang, Christian Buchbender, Gerald Antoch, Lino M. Sawicki
Summary: This study compared the diagnostic performance of different imaging techniques in detecting bone metastases in patients with primary breast cancer. [F-18]FDG PET/MRI and MRI alone showed significantly higher sensitivity and specificity than CT and bone scintigraphy; CT and bone scintigraphy had lower sensitivity in detecting bone metastases and were prone to false-positive results.
EUROPEAN RADIOLOGY
(2021)
Article
Gastroenterology & Hepatology
Lillian Du, Pernilla D'Souza, Aducio Thiesen, Safwat Girgis, Richard Owen, Dermot McNally, Philippe Sarlieve, Gurpal Sandha
Article
Gastroenterology & Hepatology
Sergio Zepeda-Gomez, Richard Sultanian, Christopher Teshima, Gurpal Sandha, Sander Van Zanten, Aldo J. Montano-Loza
Article
Gastroenterology & Hepatology
Turki AlAmeel, Vincent Bain, Gurpal Sandha
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2013)
Article
Gastroenterology & Hepatology
Pernilla M. D'Souza, Gurpal S. Sandha, Christopher W. Teshima
DIGESTIVE DISEASES AND SCIENCES
(2013)
Review
Gastroenterology & Hepatology
Christopher W. Teshima, Gurpal S. Sandha
WORLD JOURNAL OF GASTROENTEROLOGY
(2014)
Article
Gastroenterology & Hepatology
Christopher W. Teshima, Sergio Zepeda-Gomez, Suliman H. AlShankiti, Gurpal S. Sandha
WORLD JOURNAL OF GASTROENTEROLOGY
(2014)
Article
Gastroenterology & Hepatology
Yidan Lu, Alan N. Barkun, Myriam Martel
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2014)
Article
Medicine, Research & Experimental
Yen-I Chen, Kashi Callichurn, Avijit Chatterjee, Etienne Desilets, Donnellan Fergal, Nauzer Forbes, Ian Gan, Sana Kenshil, Mouen A. Khashab, Rastislav Kunda, Eric Lam, Gary May, Rachid Mohamed, Jeff Mosko, Sarto C. Paquin, Anand Sahai, Gurpal Sandha, Christopher Teshima, Alan Barkun, Jeffrey Barkun, Ali Bessissow, Kristina Candido, Myriam Martel, Corey Miller, Kevin Waschke, George Zogopoulos, Clarence Wong
Article
Gastroenterology & Hepatology
Usman Khan, Rishad Khan, Eric Benchimol, Misbah Salim, Jennifer Telford, Robert Enns, Rachid Mohamed, Nauzer Forbes, Gurpal Sandha, Ali Kohansal, Jeffrey Mosko, Avijit Chatterjee, Gary May, Kevin Waschke, Alan Barkun, Paul D. James
Summary: This study aimed to examine the learning curves and achievement of competence for Canadian advanced endoscopy trainees (AETs) using an ERCP assessment tool. The study found that Canadian AETs are graduating from fellowship programs with acceptable levels of competence for overall ERCP performance and specific tasks, although supplemental training may be required for tissue sampling.
ENDOSCOPY INTERNATIONAL OPEN
(2022)
Article
Gastroenterology & Hepatology
Vincent Palmieri, Alan Barkun, Nauzer Forbes, Myriam Martel, Eric Lam, Jennifer Telford, Gurpal Sandha, Sarto Paquin, Anand Sahai, Yen- Chen
Summary: This study evaluated the practice of EUS-BD and identified barriers to its widespread adoption. The uptake of EUS-BD as a first-line treatment for MDBO was low, mainly due to lack of high-quality data, fear of adverse events, and limited access to EUS-BD dedicated devices. In salvage situations following failed ERCP, most favored EUS-BD, but in potentially resectable disease, the percutaneous approach was preferred due to concerns about complicating future surgery.
ENDOSCOPIC ULTRASOUND
(2023)
Article
Immunology
Kevin Verhoeff, Braulio A. Marfil-Garza, Gurpal Sandha, David Cooper, Khaled Dajani, David L. Bigam, Blaire Anderson, Tatsuya Kin, Anna Lam, Doug O'Gorman, Peter A. Senior, Camillo Ricordi, A. M. James Shapiro
Summary: This study evaluated patients receiving extrahepatic or intraportal islet transplantation. The results indicate that intraportal islet infusion remains the gold standard for clinical transplantation, with superior engraftment, graft function, and glycemic outcomes compared to extrahepatic transplantation.
Review
Gastroenterology & Hepatology
John Eccles, Edward Wiebe, Pernilla D'Souza, Gurpal Sandha
ENDOSCOPY INTERNATIONAL OPEN
(2019)
Meeting Abstract
Gastroenterology & Hepatology
Gurpal Sandha, Sana Kenshil, Simrat Sandha, Christopher Teshima, Pernilla D'Souza
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2016)
Meeting Abstract
Gastroenterology & Hepatology
Pernilla M. D'Souza, Aducio Thiesen, Richard J. Owen, Philippe Sarlieve, Dermot McNally, Gurpal Sandha
Meeting Abstract
Gastroenterology & Hepatology
Richa Chibbar, Pernilla D'Souza, Gurpal Sandha, Sergio Zepeda-Gomez, Sander Veldhuyzen van Zanten, Christopher W. Teshima, Richard A. Sultanian