Article
Surgery
Katrin Schwameis, Shahin Ayazi, Ping Zheng, Andrew D. Grubic, Madison Salvitti, Toshitaka Hoppo, Blair A. Jobe
Summary: The study found that magnetic sphincter augmentation (MSA) is effective in patients with severe GERD and leads to significant clinical improvement across the spectrum of disease severity.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2021)
Article
Gastroenterology & Hepatology
Milena Nikolic, Aleksa Matic, Joy Feka, Lisa Gensthaler, Ivan Kristo, Bogdan Osmokrovic, Franz M. Riegler, Berta O. Mosleh, Sebastian F. Schoppmann
Summary: The study demonstrated the significant improvement of GERD-related symptoms and quality of life in patients with weakly acidic reflux after magnetic sphincter augmentation, with very low postoperative morbidity.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Article
Surgery
Colin P. Dunn, Jasmine Zhao, Jennifer C. Wang, Tanu A. Patel, Luke R. Putnam, Aleeson Eka, Caitlin C. Houghton, Nikolai A. Bildzukewicz, John C. Lipham
Summary: Magnetic sphincter augmentation in conjunction with large hiatal hernia repairs for patients with GERD achieves excellent long-term radiographic and clinical results, and a low overall need for reoperation, without the need for mesh.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Multidisciplinary Sciences
Ramona Schuler, Matthias Goos, Andreas Langer, Maximilian Meisinger, Christoph Marquardt, Helga Fritsch, Marko Konschake
Summary: This preclinical study investigates the technical feasibility of a new method for intraoperative pelvic neuromonitoring. By directly stimulating pelvic nerves and measuring tissue impedance, the study successfully identifies pelvic nerves in the surgical area, providing a reliable basis for preserving these nerves.
SCIENTIFIC REPORTS
(2022)
Article
Gastroenterology & Hepatology
Soichiro Matsuda, Mototsugu Kato, Yuko Sakakibara, Hiroshige Hamada, Yoshihiro Sasaki, Hideki Mori, Yuichiro Hirai, Shuji Inoue, Tatsuya Toyokawa, Takashi Kagaya, Toshio Kuwai, Naoki Esaka, Haruhiro Yamashita, Noriko Watanabe, Mio Matsumoto, Hiroyuki Fujii, Mamiko Demura, Kimitoshi Kubo, Katsuhiro Mabe, Naohiko Harada
Summary: This study demonstrates that administering vonoprazan once every second day is an effective alternative to proton pump inhibitors in the maintenance treatment of erosive GERD.
JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Surgery
Rebeca Dominguez-Profeta, Joslin N. Cheverie, Rachel R. Blitzer, Arielle M. Lee, Lauren McClain, Ryan C. Broderick, Bryan J. Sandler, Garth R. Jacobsen, Santiago Horgan, David C. Kunkel
Summary: Factors predicting dysphagia following Magnetic Sphincter Augmentation (MSA) include peristaltic reserve assessed by Multiple Rapid Swallows (MRS) during high-resolution esophageal manometry (HRM) and the size of the MSA implant. An adequate peristaltic reserve and a larger device size correlate with a decreased incidence of postoperative dysphagia, without compromising the anti-reflux barrier. Routine assessment of peristaltic reserve with preoperative HRM should be considered prior to MSA placement.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Biochemistry & Molecular Biology
Boram Cha, Hyejin Kim, Van Gia Truong, Sun-Ju Oh, Seok Jeong, Hyun Wook Kang
Summary: Gastroesophageal reflux disease (GERD) is a global health issue, and this study evaluated the feasibility of endoscopic balloon-assisted laser treatment (EBLT) in a porcine model. GERD was induced in three animals via botulinum toxin injection into the lower esophageal sphincter (LES), and a week later, EBLT was performed on the GERD models. The EBLT demonstrated thicker and shorter LES muscle layers compared to the controls, while still maintaining LES pressure. Histological analysis revealed that EBLT reinforced the muscularis layer with preserved mucosa and mild remodeling of intermuscular collagen in the LES. This study highlights the potential of EBLT as a new endoscopic approach for treating GERD, with further research needed to assess its efficacy and safety in a larger sample size.
Article
Biology
Bowen Ren, Zhenchuan Han, Wenyi Li, Jianheng Liu
Summary: Bone cement is important for treating bone metastasis defects, but its anti-tumor effect is limited. Magnetic bone cement can not only support bone defects but also achieve magnetic hyperthermia. By mixing magnetic nanoparticles with good biocompatibility and high heating efficiency, the physicochemical properties of the bone cement can be maintained while meeting the requirements of hyperthermia therapy.
Article
Gastroenterology & Hepatology
Emily M. Mackay, Brian E. Louie
Summary: The surgical management of GERD has evolved from focusing on hiatal hernias and crural closure to surgical augmentation of the lower esophageal sphincter. The role of crural closure has been rediscovered in re-establishing intra-abdominal esophageal length and contributing to normal LES pressures.
DISEASES OF THE ESOPHAGUS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ji Sook Kim, Hyun-Hae Cho, Ji-Yeon Shin, Sook-Hyun Park, Yu-Sun Min, Byunggeon Park, Jihoon Hong, Seo Young Park, Myong-Hun Hahm, Moon Jung Hwang, So Mi Lee
Summary: The study investigates the predictability of synthetic relaxometry for neurodevelopmental outcomes in premature infants and evaluates the performance of combining relaxation times with clinical variables or qualitative MRI abnormalities. The results show that prolonged T1-frontal/parietal and T2-parietal periventricular white matter, moderate-to-severe white matter abnormality, and bronchopulmonary dysplasia are significantly associated with moderate/severe disability. The combination of clinical variables and T1-parietal PVWM or MRI finding and T1-frontal PVWM improves prediction compared to individual models.
EUROPEAN RADIOLOGY
(2023)
Article
Clinical Neurology
Marissa Grande, Lucas Lattanzio, Isabelle Buard, Allison M. McKendrick, Yu Man Chan, Victoria S. Pelak
Summary: Visual Snow (VS) syndrome is believed to be caused by aberrant central visual processing, with studies suggesting excessive neuronal activity in the medial temporal lobe. A pilot study at the University of Colorado School of Medicine aims to investigate the use of rTMS intervention to improve symptoms and visual dysfunction associated with VS. The study protocol includes 10 rTMS sessions over a 2-week period for up to 10 participants meeting VS criteria, with assessments pre- and post-treatment to evaluate outcomes.
FRONTIERS IN NEUROLOGY
(2021)
Article
Gastroenterology & Hepatology
Jiaoyang Lu, Feixue Chen, Xiaofen Lv, Baoling Tian, Ruozi Pan, Rui Ji, Jianrong Bai, Xiuli Zuo, Yanqing Li, Xuefeng Lu
Summary: In this study, the novel endoscopic procedure called antireflux mucosal valvuloplasty (ARMV) showed to be a safe, feasible, and effective treatment for patients with gastroesophageal reflux disease (GERD). The procedure successfully reduced acid exposure and improved GERD symptoms and quality of life in the majority of patients. Further prospective and comparative trials are needed to confirm the role of ARMV among endoscopic antireflux therapies.
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Medicine, General & Internal
Christopher Dawoud, Leonhard Bender, Kerstin Melanie Widmann, Felix Harpain, Stefan Riss
Summary: Sphinkeeper implantation is a promising surgical technique for severe fecal incontinence, with low complication rates and short-term functional improvement. However, implant migration is commonly observed in patients undergoing this procedure.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Stefania Montemezzi, Giuseppe Cardano, Silvia Storer, Nicolo Cardobi, Carlo Cavedon, Lucia Camera
Summary: This study demonstrates the feasibility and efficacy of using DWI in MRI-guided breast biopsies for accurate lesion targeting and device positioning. DWI can effectively detect both mass and non-mass lesions with a minimum size of 5 mm.
EUROPEAN RADIOLOGY
(2021)
Article
Clinical Neurology
Hannelore L. N. Tandt, Nele van de Velde, Sara De Witte, Kurt Audenaert, Chris Baeken, Gilbert M. D. Lemmens
Summary: This study found that LF rTMS targeting the dmPFC may improve OCD, anxiety, and depressive symptoms in treatment-resistant OCD patients, and it is a safe and well-tolerated treatment.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2021)