Nutritional Support in the Severely Compromised Motility Patient: When and How?

The management of chronic intestinal pseudo-obstruction (CIPO) remains difficult and requires a multidisciplinary approach. In adult patients with CIPO on home parenteral nutrition (HPN), the 10-year survival rate was 68%. Long-term HPN dependence does not seem to be associated with a significant increase in mortality and morbidity. HPN could be a safe and efficient approach to the management of intestinal failure caused by CIPO, with restoring oral intake and lowering hospitalization frequency as major goals of treatment.