Review
Gastroenterology & Hepatology
Benjamin Lebwohl, Alberto Rubio-Tapia
Summary: The incidence of celiac disease is increasing due to both improved recognition and a real increase of the disorder. The reasons for this true rise are unclear, but may be related to environmental factors. Early-life gluten exposure is a major focus of prevention efforts.
Article
Pediatrics
Jessica Whitburn, Srinivasa R. Rao, Siba Prosad Paul, Bhupinder Kaur Sandhu
Summary: This study aimed to investigate the differences in diagnosis rates of CD in children from different socioeconomic groups and found that while the diagnosed incidence of CD has increased over time, 83-91% remain undiagnosed. Children from socioeconomically deprived backgrounds are more likely to be underdiagnosed, and the gap between the least and most deprived has widened. To address the massive underdiagnosis, further strategies, including pilot studies using finger prick serological mass screening for CD in children entering primary schools, are needed.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Article
Chemistry, Analytical
Nicole M. Ralbovsky, Igor K. Lednev
Summary: This study utilized Raman hyperspectroscopy to identify celiac disease in red blood cells, aiming to develop a noninvasive, cost-effective, accurate, and reliable diagnostic method. Through partial least squares discriminant analysis (PLS-DA) and ROC curve analysis, the method achieved 100% successful external validation at the individual donor level.
Review
Radiology, Nuclear Medicine & Medical Imaging
Xin-yue Wang, Zhoulei Li, Si-yun Huang, Xiao-di Shen, Xue-hua Li
Summary: Celiac disease is an immune-mediated small bowel disease triggered by exposure to gluten. A strict gluten-free diet is the primary treatment, but some patients may not respond well. Cross-sectional imaging techniques, such as CT and MRI, play an important role in the diagnosis and management of CD.
EUROPEAN RADIOLOGY
(2023)
Review
Medicine, General & Internal
Aleksandra Medza, Agnieszka Szlagatys-Sidorkiewicz
Summary: This review summarizes the findings on the nutritional status of patients with celiac disease (CD). Malnutrition, including over- and undernutrition, is common in CD patients at diagnosis and during treatment. Clinical presentations of CD vary widely, and evaluating nutritional parameters is beneficial for defining dietary needs and developing a balanced diet. A gluten-free diet (GFD) is the cornerstone of CD therapy, improving nutritional status, but malnutrition and metabolic consequences may still occur.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Immunology
Andrea Costantino, Marco Michelon, Leda Roncoroni, Luisa Doneda, Vincenza Lombardo, Claudio Costantino, Maurizio Vecchi, Luca Elli
Summary: This study investigated vaccination coverage and attitudes among celiac disease (CD) patients. It found that most patients had a positive attitude towards vaccines, but a significant minority had a negative or partially negative attitude. Some patients were not vaccinated against certain diseases potentially harmful to CD due to hesitancy or lack of recommendation from physicians.
Article
Nutrition & Dietetics
Klaudia Urbaszek, Natalia Drabinska, Anna Szaflarska-Poplawska, Elzbieta Jarocka-Cyrta
Summary: Persistent iron-deficient anemia is uncommon in pediatric patients with celiac disease, and there is no significant association between the rs855791 genotype and persistent IDA.
Article
Green & Sustainable Science & Technology
Mohan Zhang, Yun Hu, Yuanna Hu
Summary: Previous studies have shown positive correlations between family socioeconomic status, parental educational expectations, and children's academic performance. However, further research is needed to confirm the mediating effects of teacher-parent communication on the relationship between socioeconomic status and parental educational expectations. This study employs multilevel path analysis to explore the mediating and moderating mechanisms between socioeconomic status and educational expectations, considering the factors of teacher-parent communication and coronavirus anxiety. The findings illustrate the positive influence of socioeconomic status on parental educational expectations, the mediating role of teacher-parent communication, and the moderating effect of coronavirus anxiety on the relationship between socioeconomic status and teacher-parent communication. The study emphasizes the significance of teacher-parent communication in reflecting the connection between socioeconomic status and educational expectations in Chinese families, particularly in the post-COVID-19 era. The practical implications of these findings for parents, teachers, and schools are discussed.
Article
Biochemistry & Molecular Biology
Andres Bodas, Oscar Perez, Paula Martin, Alejandro Junguito, Rafael Sanchez, Maria Victoria Blanco, Montserrat Gonzalez-Estecha
Summary: The aim of this study was to determine the levels of iron, vitamins, and minerals prior to the diagnosis of celiac disease and non-celiac gluten sensitivity, and to investigate the effect of a gluten-free diet on these parameters. The results showed that calcium levels increased in celiac patients after 3 months of gluten-free diet, and ferritin levels increased significantly in patients with non-celiac gluten sensitivity. No significant changes were observed in the rest of the parameters, possibly due to early diagnosis and minimal analytical alterations.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2023)
Article
Endocrinology & Metabolism
Pei-Lun Xiao, Cairen Fuerwa, Chi-Jen Hsu, Rong Peng, Ai-Yong Cui, Ning Jiang, Yong-Guang Ma, Xiang-He Xu, Hua-Ding Lu
Summary: The association between socioeconomic status and bone mineral density in American men was investigated in this study. The results showed a positive correlation between socioeconomic status and lumbar spine bone mineral density. This finding is clinically significant for the prevention and treatment strategies of osteoporosis.
OSTEOPOROSIS INTERNATIONAL
(2022)
Article
Computer Science, Cybernetics
Mustafa Kerem Kobul
Summary: The term 'digital native' has gained popularity in educational research, referring to the younger generation born after the 1980s who are presumed to be technologically savvy. However, this study found that not all young individuals possess the same level of technological skills, as their internet usage patterns are influenced by their parents' education level.
BEHAVIOUR & INFORMATION TECHNOLOGY
(2023)
Article
Gastroenterology & Hepatology
Mohammad El Mouzan, Asaad Assiri, Ahmed Al Sarkhy
Summary: This study evaluated the predictive power of the gut microbiota in the diagnosis of celiac disease (CeD) and identified important taxa that can help distinguish CeD patients from controls. The combination of fecal bacteria and viruses showed a stronger predictive power in the diagnosis of CeD. Two bacteria in fecal samples and one virus in mucosal samples were predicted to be important biomarkers for differentiating celiac from nonceliac disease groups.
WORLD JOURNAL OF GASTROENTEROLOGY
(2023)
Review
Food Science & Technology
Chao Lu, Weihua Zhou, Xinjue He, Xinxin Zhou, Chaohui Yu
Summary: The study found that patients with celiac disease have lower Vitamin D levels compared to controls, which improve after treatment, but there is no difference in Vitamin D Receptor genotypes between the two groups.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Nutrition & Dietetics
Catalina Ballestero-Fernandez, Gregorio Varela-Moreiras, Natalia Ubeda, Elena Alonso-Aperte
Summary: Individuals with celiac disease following a long-term gluten-free diet have deficiencies in several key nutrients, including folates, vitamin D, calcium, vitamin E, iodine, and iron. Some celiac patients may be more at risk for osteopenia and osteoporosis. However, the overall nutritional status and dietary patterns of celiac individuals did not significantly differ from those of healthy volunteers in the study population. Regular monitoring and assessment of nutrient levels should be conducted in the celiac population.
Article
Gastroenterology & Hepatology
Fabiana Zingone, Erica Secchettin, Ilaria Marsilio, Flavio Valiante, Valerio Zorzetto, Giovanni Cataudella, Anna D'Odorico, Cristina Canova
Summary: The study aimed to describe the profiles of adult patients with newly diagnosed celiac disease (CeD) and their association with quality of life and psychological symptoms. Results showed that symptomatic presentation, diagnostic delay, and gender may affect quality of life and psychological disorders in CeD patients.
DIGESTIVE AND LIVER DISEASE
(2021)