Article
Nutrition & Dietetics
Caterina Strisciuglio, Sabrina Cenni, Maria Rosaria Serra, Pasquale Dolce, Sanja Kolacek, Sara Sila, Ivana Trivic, Michal Rozenfeld Bar Lev, Raanan Shamir, Aco Kostovski, Alexandra Papadopoulou, Eleftheria Roma, Christina Katsagoni, Danijela Jojkic-Pavkov, Angelo Campanozzi, Elena Scarpato, Erasmo Miele, Annamaria Staiano
Summary: 《Mediterranean diet has a protective effect on functional gastrointestinal disorders》
Review
Medicine, General & Internal
Angharad Vernon-Roberts, India Alexander, Andrew S. Day
Summary: Functional gastrointestinal disorders (FGID) are common in children, with varying prevalence rates across different age groups. The most common types of FGID differ among infants, toddlers, and older children, serving as benchmark and comparative data for the general population and those with comorbid conditions.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Nutrition & Dietetics
Hsun-Chin Chao
Summary: The benefits of zinc in treating pediatric gastrointestinal diseases, particularly inflammatory bowel disease and celiac disease, are significant. Zinc supplementation has been shown to reduce the duration of diarrhea and may also be beneficial for peptic ulcer disease and gastroesophageal reflux disease. However, specific guidelines for zinc supplementation in children are lacking.
Article
Gastroenterology & Hepatology
Miriam B. Vos, Mark L. Van Natta, Niviann M. Blondet, Srinivasan Dasarathy, Mark Fishbein, Paula Hertel, Ajay K. Jain, Saul J. Karpen, Joel E. Lavine, Saeed Mohammad, Laura A. Miriel, Jean P. Molleston, Marialena Mouzaki, Arun Sanyal, Emily P. Sharkey, Jeffrey B. Schwimmer, James Tonascia, Laura A. Wilson, Stavra A. Xanthakos
Summary: This study aimed to evaluate the effect of losartan on ALT levels in children with NAFLD. The results showed that losartan did not significantly reduce ALT levels, but it did significantly decrease alkaline phosphatase and systolic blood pressure.
Review
Pediatrics
Manuela Capozza, Nicola Laforgia, Valentina Rizzo, Silvia Salvatore, Stefano Guandalini, Mariella Baldassarre
Summary: Assessment and management of pain are important in pediatric care. Probiotics have been proposed as a potential treatment for functional gastrointestinal disorders in children, but the current evidence is inadequate to support their clinical use.
FRONTIERS IN PEDIATRICS
(2022)
Article
Gastroenterology & Hepatology
Jayendra Seetharaman, Ujjal Poddar, Surender Kumar Yachha, Anshu Srivastava, Moinak Sen Sarma
Summary: This open-label trial evaluated the efficacy of amitriptyline in pediatric functional abdominal pain disorder (FAPD). The results showed that amitriptyline significantly improved pain and quality of life compared to placebo. Amitriptyline was the only factor predictive of treatment response. This study suggests that more frequent use of amitriptyline in clinical settings is warranted due to its safety and efficacy.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Toxicology
B. Hu, Y. Kuang, Y. Jing, Y. Li, H. Zhao, H. Ouyang
Summary: Children with allergic rhinitis and functional gastrointestinal disease have imbalanced intestinal microbiota and gastrointestinal peptide levels, which can be improved by treatment with glutamine and probiotics, leading to restored intestinal barrier function.
HUMAN & EXPERIMENTAL TOXICOLOGY
(2021)
Review
Nutrition & Dietetics
Silvia Salvatore, Maria Serena Battigaglia, Elena Murone, Eugenia Dozio, Licia Pensabene, Massimo Agosti
Summary: Dietary fibers have immune, cardiovascular, metabolic, and intestinal beneficial effects. They can be found naturally in fruits, vegetables, legumes, and cereals or be used as supplements. Soluble fibers are digested by gut bacteria and have prebiotic effects, while non-soluble fibers improve intestinal transit. The amount and characteristics of fiber requirement in infants and children need further investigation, and the use of fibers in children with gastrointestinal disorders is still limited.
Review
Nutrition & Dietetics
Teresa Di Chio, Christiane Sokollik, Diego G. Peroni, Lara Hart, Giacomo Simonetti, Franziska Righini-Grunder, Osvaldo Borrelli
Summary: Nutritional management in pediatric gastrointestinal diseases is increasingly popular, with disease-specific diets as conventional treatments. Nutritional support is crucial for maintaining growth and improving outcomes, but dietary modifications may have negative consequences. Expert supervision is advised to prevent misconceptions and potential adverse effects from diet modification.
Article
Gastroenterology & Hepatology
Claudio Romano, Socrate Pallio, Ugo Cucinotta, Paola Accorsi, Valeria Dipasquale
Summary: This article discusses the use of PHGG fiber in the treatment of pediatric FGIDs, especially for malnourished children. It is considered to be an effective complementary therapy and can be used as a component of nutritionally complete formulas.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Guglielmo Gallone, Luca Baldetti, Filippo Angelini, Andrea Saglietto, Matteo Bellettini, Alessandro Beneduce, Viola Ranotti, Mauro Chiarito, Pier Pasquale Leone, Matteo Pagnesi, Ovidio De Filippo, Federico Landra, Francesco Bruno, Giorgio Marengo, Massimo Collino, Giuseppe Ferrante, Giulio G. Stefanini, Antonio Colombo, Rasha Al-Lamee, Darrel P. Francis, Marc E. Jolicoeur, Timothy D. Henry, Francesco Giannini, Fabrizio D'Ascenzo, Gaetano Maria De Ferrari
Summary: This study conducted a systematic review and meta-analysis to quantify the effect of placebo on symptoms, life quality, and functional outcomes in randomized placebo-controlled trials of symptomatic stable coronary artery disease. The results showed that placebo had a substantial effect on various metrics, but the size of the placebo effect varied significantly.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Food Science & Technology
Wolfgang J. Schnedl, Dietmar Enko
Summary: In western countries, a significant portion of the population may experience adverse reactions to certain food components, leading to various gastrointestinal issues. Thus, a thorough diagnostic workup is necessary for managing patients with functional gastrointestinal complaints, including consideration of individual tolerance to different food components.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Gastroenterology & Hepatology
Sophie Parker, Olafur Palsson, David S. Sanders, Magnus Simren, Ami D. Sperber, Hans Tornblom, Heidi Urwin, William Whitehead, Imran Aziz
Summary: Individuals with celiac disease can experience gastrointestinal symptoms despite adhering to a gluten-free diet. This study found that half of the individuals with celiac disease who adhered to a gluten-free diet had functional gastrointestinal disorders, which was twice the rate compared to a matched control group. Furthermore, these individuals were more likely to have anxiety, depression, somatization, and reduced quality of life. Addressing gut-brain interaction disorders may improve outcomes in this specific group of patients.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Pediatrics
Valeria Dipasquale, Stefano Passanisi, Ugo Cucinotta, Antonio Cascio, Claudio Romano
Summary: During the COVID-19 pandemic, the diagnosis and management of gastrointestinal diseases in pediatric population may need adjustments, including the recommendation of telemedicine services and postponement of non-urgent endoscopic procedures.
ITALIAN JOURNAL OF PEDIATRICS
(2021)
Review
Oncology
Marta Andrzejewska, Jakub Czarny, Katarzyna Derwich
Summary: This article reviews the latest updates on the management of pediatric gastrointestinal tumors, focusing on the advances in molecular biology of the disease and discussing emerging treatment with kinase inhibitors as targeted therapy.
