Article
Medicine, Research & Experimental
Seh Ling Kwong, Ester G. Hernandez, Katharina Winiker, Kristin Gozdzikowska, Phoebe Macrae, Maggie-Lee Huckabee
Summary: This study examined the effect of topical nasal anesthetic (TNA) on swallowing and tolerability during high-resolution impedance manometry (HRIM) with a 4.2-mm catheter. The results showed that TNA did not improve comfort or significantly affect swallowing behavior during the procedure.
Article
Gastroenterology & Hepatology
Marinde van Lennep, Marin L. Leijdekkers, Jac M. Oors, Marc A. Benninga, Michiel P. van Wijk, Maartje M. J. Singendonk
Summary: Pediatric esophageal function tests are interpretable in more than 90% of cases overall, with differences between age groups. In children under 4 years of age, all patients had imperfections in HRM and 3/8 tests were uninterpretable. HRM in older children and pH-MII+/-mano were interpretable in the vast majority.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2021)
Review
Gastroenterology & Hepatology
Michael Yodice, Alexandra Mignucci, Virali Shah, Christopher Ashley, Micheal Tadros
Summary: Surgical treatment with fundoplication is a viable option for GERD patients, but thorough pre-operative assessment is crucial. Newer technologies can help clinicians identify patients with true LES dysfunction, which is useful for assessing surgical outcomes.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Surgery
Theresa N. Wang, Jennifer Underhill, Robert Tamer, Kyle A. Perry, Kelly R. Haisley
Summary: This study aimed to investigate the correlation between IP and HRM in the pre-operative evaluation of GERD. The results showed that IP had a sensitivity of 65.8% and a specificity of 50% in detecting normal motility.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Gastroenterology & Hepatology
Mentore Ribolsi, Matteo Ghisa, Edoardo Savarino
Summary: The article discusses investigations conducted using conventional manometry and high-resolution manometry (HRM) to explore the field of esophageal motility and understand the potential link between motor features and gastroesophageal reflux disease (GERD) pathogenesis. HRM studies have provided insights into the esophageal motor function in patients with various esophageal disorders, as well as the correlation between reduced esophageal motility, disruption of the esophagogastric junction, and gastroesophageal reflux burden.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Asad Jehangir, Zubair Malik, Henry P. Parkman
Summary: This study aimed to examine the correlation between reflux observed on esophagogastric junction (EGJ) during high-resolution esophageal manometry with impedance (HREMI) and reflux on conventional esophageal reflux monitoring studies. The results showed that about 20.5% of patients undergoing HREMI had pathologic reflux at EGJ. Patients with reflux on HREMI more frequently had gastroesophageal reflux disease (GERD) on ambulatory pH monitoring. However, reflux on HREMI had low sensitivity for GERD.
BMC GASTROENTEROLOGY
(2022)
Article
Gastroenterology & Hepatology
Mentore Ribolsi, Edoardo Savarino, Marzio Frazzoni, Michele Cicala
Summary: This study used both conventional and new impedance-pH parameters as predictors of response to label-dose PPI in typical GERD. The mean nocturnal baseline impedance (MNBI) and PSPW index were found to be significantly associated with PPI responsiveness. It was concluded that the novel MII-pH variables together with pathological factors are highly predictive of response to label-dose PPI in typical GERD syndrome.
DIGESTIVE AND LIVER DISEASE
(2023)
Article
Critical Care Medicine
Karel Balihar, Jan Kotyza, Lucie Zdrhova, Jana Kozeluhova, Michal Krcma, Martin Matejovic
Summary: Motility disorders of upper gastrointestinal tract are common in critical illness and vary according to gastric emptying status. Metoclopramide reduced esophageal activities but did not affect reflux episodes in critically ill patients.
Article
Acoustics
Kelly N. Jahn
Summary: Hyperacusis is a perceptual consequence of acoustic overexposure that can have debilitating effects on quality of life. However, there is a lack of objective biomarkers and standardized assessment protocols for hyperacusis. Current conventional audiologic tests are unable to adequately capture the multifaceted nature of the condition. This review discusses clinical and investigational tools for diagnosing and monitoring hyperacusis, as well as potential tools for future trials.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2022)
Article
Medicine, Research & Experimental
Ilan Palte, Sarah Stewart, Hal Rives, James A. Curtis, Necati Enver, Andrew Tritter, Katerina Andreadis, Valentina Mocchetti, Felice Schnoll-Sussman, Amir Soumekh, Rasa Zarnegar, Philip Katz, Anais Rameau
Summary: The study aimed to investigate the effects of using virtual reality (VR) on pain and anxiety in patients with dysphagia undergoing high-resolution esophageal manometry (HRM). The results showed that the use of VR significantly reduced anxiety and physiological pain responses, suggesting that VR can be used as a distraction tool to improve patient comfort during HRM.
Article
Surgery
D. M. Felsenreich, M. L. Zach, N. Vock, J. Jedamzik, J. Eichelter, M. Mairinger, L. Gensthaler, L. Nixdorf, P. Richwien, C. Bichler, I. Kristo, F. B. Langer, G. Prager
Summary: This study aims to objectively evaluate reflux and esophagus motility in primary OAGB patients by comparing preoperative and postoperative mid-term outcomes. The results showed a decrease in acid reflux and an increase in non-acid reflux. Gastroscopy also revealed signs of chronic irritation. Follow-up gastroscopies after 5 years may be considered for OAGB patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Gastroenterology & Hepatology
Taher Omari, Charles Cock, Peter Wu, Michal Marcin Szczesniak, Mistyka Schar, Jan Tack, Nathalie Rommel
Summary: This study aimed to establish a methodology for diagnosing oropharyngeal disorders using P-HRM-I. The results showed that UES relaxation pressure was the best indicator for differentiating patients from controls and diagnosing UES disorders. A diagnostic scheme was also devised to identify patients with UES disorder or propulsive disorder. Additionally, the study found that patients with pharyngeal pressurizations and evidence of reduced UES relaxation and/or distensibility had higher aspiration scores.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Boram Cha, Kyungmin Choi, Kee Wook Jung, Hwa Jung Kim, Ga Hee Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Don Choi, Do Hoon Kim, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Segyeong Joo
Summary: This study compared two diagnostic tools for non-obstructive dysphagia (NOD) and found that the volume of inverted impedance (VII) ratio is more reliable than the esophageal impedance integral (EII) ratio.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Jan Tack, Ans Pauwels, Sabine Roman, Edoardo Savarino, Andre Smout
Summary: A European consensus was developed on the clinical application of esophageal high-resolution manometry (HRM), providing guidance on when to consider HRM, how to perform it, and how to interpret the results. Areas of uncertainty and lack of consensus were identified, particularly in terms of treatment implications, highlighting the need for future research in this area.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Health Care Sciences & Services
Gang-Hua Lin, Kuan-Hsun Lin, Szu-Yu Lin, Tsai-Wang Huang, Hung Chang, Hsu-Kai Huang
Summary: Esophageal motility disorders are a significant cause of nonobstructive dysphagia. Our study investigated the clinical characteristics of patients in Taiwan who underwent HRIM and analyzed the therapeutic outcomes of those who received surgical interventions.
JOURNAL OF PERSONALIZED MEDICINE
(2022)