Article
Gastroenterology & Hepatology
Chang Seok Ko, Nam Ryong Choi, Byung Sik Kim, Jeong Hwan Yook, Min-Ju Kim, Beom Su Kim
Summary: TLTG with the modified overlap method resulted in earlier discharge, faster bowel and diet recovery, and lower pain scores compared to OTG; similar complication rates and oncological outcomes were observed between groups; obesity, high ASA scores, and older age were independent risk factors for early complications.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Surgery
Hylke J. F. Brenkman, Linda Claassen, Gerjon Hannink, Leonie R. van der Werf, Jelle P. -H. Ruurda, Grard A. P. Nieuwenhuizen, Misha D. P. Luyer, Ewout A. Kouwenhoven, Marc J. van Det, Mark I. van Berge Henegouwen, Suzanne S. Gisbertz, Jan H. M. B. Stoot, Karel W. E. Hulsewe, Frans van Workum, Richard van Hillegersberg, Camiel Rosman
Summary: This study evaluated the learning curve of laparoscopic gastrectomy (LG) in the Netherlands and found that there was no significant learning curve effect for anastomotic leakage, but there was a learning curve effect for overall complications and conversion rate.
Article
Medicine, General & Internal
Philippa Seika, Matthias Biebl, Jonas Raakow, Dino Kroell, Candan Cetinkaya-Hosgoer, Peter Thuss-Patience, Max Magnus Maurer, Eva Maria Dobrindt, Johann Pratschke, Christian Denecke
Summary: Experienced laparoscopic surgeons require a minimum of 44 cases to achieve technical competence for performing total gastrectomy. After completing the learning curve, the operation time decreases, but quality criteria remains unchanged.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Surgery
Erica Sakamoto, Andre Roncon Dias, Marcus Fernando Kodama Pertille Ramos, Amir Zeide Charruf, Ulysses Ribeiro-Junior, Bruno Zilberstein, Ivan Cecconello
Summary: The increased incidence of Remnant Gastric Cancer (RGC) has raised the demand for Laparoscopic Completion Total Gastrectomy (LCTG). LCTG is technically challenging even for experienced surgeons. This study describes a standard technique and reports early experience with LCTG.
JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES
(2021)
Article
Surgery
Han-Kwang Yang, Woo Jin Hyung, Sang-Uk Han, Young-Jun Lee, Joong-Min Park, Gyu Seok Cho, Oh Kyoung Kwon, Seong-Ho Kong, Hyoung-Il Kim, Hyuk-Joon Lee, Wook Kim, Seung Wan Ryu, Sung-Ho Jin, Sung Jin Oh, Keun Won Ryu, Min-Chan Kim, Hye Seong Ahn, Young Kyu Park, Yong Ho Kim, Sun-Hwi Hwang, Jong Won Kim, Jin-Jo Kim
Summary: This single-arm multicenter phase II clinical trial in Korea evaluated the safety and feasibility of laparoscopic total gastrectomy for clinical stage I proximal gastric cancer, with a focus on different methods of esophagojejunostomy. The study found that extracorporeal circular stapling and intracorporeal linear stapling were safe and feasible in laparoscopic total gastrectomy, but intracorporeal circular stapling increased the risk of EJ stenosis.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Zheng-Yan Li, Jia-Jia Liu, Pei-Wu Yu, Yong-Liang Zhao, Yan Shi, Zi-Yan Luo, Bin Wu, Jun-Jie Wang, Feng Qian
Summary: In comparing the efficacy and safety of robotic total gastrectomy (RTG) with laparoscopic total gastrectomy (LTG) for carcinoma in the remnant stomach (CRS), it was found that the two procedures showed similar outcomes in terms of operation time, complications, and survival rates. However, RTG was associated with higher total costs and less estimated blood loss compared to LTG.
GASTROENTEROLOGY REPORT
(2021)
Article
Oncology
Chang Seok Ko, Jin Ho Jheong, In-Seob Lee, Beom Su Kim, Min-Ju Kim, Moon-Won Yoo
Summary: Patients in the LTG without MD group had shorter time to first flatus and soft diet postoperatively, with comparable EJ-related complication rates to the CLTG group.
JOURNAL OF GASTRIC CANCER
(2021)
Article
Surgery
Colston Edgerton, Keyvan Heshmati, Ashley Herman, Tanujit Dey, Robab Dehkharghani, Ramsis Ramsis, Malcolm Robinson, Ashley Vernon, Neil Ghushe, David Spector, Scott Shikora, Ali Tavakkoli, Eric G. Sheu
Summary: This study compared surgeons who had received fellowship training in LSG with those who had not, analyzing data on operating times and outcomes for the first 100 LSG cases of each surgeon. The results showed trained surgeons had faster and more consistent operating times, with no correlation between case number and weight loss outcomes or safety profiles for either group. This suggests that the learning curves for LSG are established during formal fellowship training.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Susie Yoon, Gyu Young Song, Jihye Lee, Ho-Jin Lee, Seong-Ho Kong, Won Ho Kim, Do Joong Park, Hyuk-Joon Lee, Han-Kwang Yang
Summary: Ultrasound-guided bilateral subcostal TAPB provides efficient postoperative analgesia with an opioid-sparing effect after laparoscopic gastrectomy, but does not significantly reduce opioid-related side effects.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Munseok Choi, Ho Kyoung Hwang, Woo Jung Lee, Chang Moo Kang
Summary: The study analyzed a total of 171 patients who underwent LPDs and found that the learning curve can be divided into three phases: initial learning period, technical competence period, and challenging period, requiring 40 and 100 cases respectively to achieve the corresponding levels of expertise.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Oncology
Chenchen Mao, Xiaodong Chen, Xiangwei Sun, Xiang Wang, Ce Zhu, Wenjing Chen, Xiangyang Xue, Xian Shen
Summary: This study compared the short- and long-term outcomes of gastric cancer patients with visceral obesity who underwent laparoscopic gastrectomy or open gastrectomy. The results showed that laparoscopic gastrectomy reduced overall complications and postoperative hospital stays, as well as improved long-term overall survival compared to open radical gastrectomy in patients with visceral obesity.
Article
Surgery
D. J. Park, Y-W Kim, H-K Yang, K. W. Ryu, S-U Han, H-H Kim, W-J Hyung, J. H. Park, Y-S Suh, O. K. Kwon, H. M. Yoon, W. Kim, Y-K Park, S-H Kong, S. H. Ahn, H-J Lee
Summary: The safety and functional benefit of laparoscopic pylorus-preserving gastrectomy (LPPG) compared with laparoscopic distal gastrectomy (LDG) remain a concern. This study evaluated short-term outcomes of a randomized clinical trial comparing LPPG with LDG for gastric cancer, showing that postoperative complications and mortality were comparable in both procedures.
BRITISH JOURNAL OF SURGERY
(2021)
Article
Oncology
Shunji Endo, Terumasa Yamada, Junji Kawada, Masaharu Higashida, Yoshinori Fujiwara, Tomio Ueno
Summary: This study demonstrates the use of intraoperative X-ray to identify tumor location and determine resection line in laparoscopic distal gastrectomy for gastric cancer, with successful outcomes in 71 patients.
ANTICANCER RESEARCH
(2023)
Article
Surgery
Koichi Suda, Miyoshi Sakai, Kazutaka Obama, Yukie Yoda, Susumu Shibasaki, Tsuyoshi Tanaka, Masaya Nakauchi, Shigeo Hisamori, Tatsuto Nishigori, Ataru Igarashi, Hirokazu Noshiro, Masanori Terashima, Ichiro Uyama
Summary: This study compares the 3-year outcomes of robotic gastrectomy (RG) and laparoscopic gastrectomy (LG) for gastric cancer treatment. The results show that RG has better 3-year overall survival rate (3yOS) compared to LG, especially for patients with pStage IA disease. Additionally, RG improves some adverse events and postoperative hospitalization.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Oncology
Chang Seok Ko, Jin Ho Jheong, Seong-A. Jeong, Byung Sik Kim, Jeong Hwan Yook, Beom Su Kim, In-Seob Lee, Chung Sik Gong, Na Young Kim, Moon-Won Yoo
Summary: This study compared the surgical and oncological outcomes between gastric cancer patients who underwent liver transplantation and curative gastrectomy, and those who only received curative gastrectomy. The results showed that there were no significant differences in overall complications between the two groups, but the liver transplantation group had longer operative time, higher transfusion frequency, and lower 5-year overall survival rate. This suggests that curative gastrectomy can be a safe treatment for gastric cancer, but further research is needed to identify the reasons for the lower survival rate in gastric cancer patients who underwent liver transplant surgery.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Surgery
So Hyun Kang, Mira Yoo, Duyeong Hwang, Eunju Lee, Sangjun Lee, Young Suk Park, Sang-Hoon Ahn, Yun-Suhk Suh, Hyung-Ho Kim
Summary: This study compared the postoperative outcomes and patient quality of life between single-incision distal gastrectomy (SIDG) and multiport laparoscopic distal gastrectomy (MLDG). The results showed no significant difference in postoperative pain scores, hospital stay, and postoperative QOL between the two groups.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Gastroenterology & Hepatology
Ho Soo Chun, Minjong Lee, Hye Ah Lee, Sejin Lee, Soyeon Kim, Ye Jun Jung, Chaewon Lee, Hyoeun Kim, Han Ah Lee, Hwi Young Kim, Kwon Yoo, Tae Hun Kim, Sang Hoon Ahn, Seung Up Kim
Summary: This study aimed to determine the relationship between sarcopenic obesity (SO) and the risk of significant liver fibrosis or cardiovascular disease (CVD) in nonalcoholic fatty liver disease (NAFLD). Through a multicenter retrospective study, it was found that high-risk subjects with SO had a higher risk of liver fibrosis and CVD development. The results demonstrated that high-risk subjects with SO had significantly increased risks of liver fibrosis and CVD development.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Medicine, General & Internal
Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin-Ha Yoon, Beom Kyung Kim
Summary: In this study, the association between long-term statin use and hepatocellular carcinoma (HCC) recurrence after surgery for hepatitis B virus (HBV)-related HCC was assessed. The study found that long-term statin use was significantly associated with reduced risk of HCC recurrence and liver-related mortality.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Gastroenterology & Hepatology
Yuna Kim, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Myung Ji Goh, Wonseok Kang, Seung Up Kim
Summary: This study compared the outcomes of sorafenib and nivolumab as second-line agents after failed lenvatinib treatment in patients with advanced HCC. The results showed that lenvatinib-sorafenib sequential treatment resulted in significantly better survival than lenvatinib-nivolumab sequential treatment.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2023)
Article
Medicine, General & Internal
Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin-Ha Yoon, Beom Kyung Kim
Summary: This study aimed to compare the postoperative recurrence of hepatocellular carcinoma (HCC) in patients with hepatitis B virus (HBV)-infected HCC who received antiviral therapy (AVT) compared to those who did not. The results showed that the recurrence rates of HCC were similar between AVT users and non-users with detectable serum HBV-DNA, regardless of the presence of liver cirrhosis. Therefore, initiating AVT based on detectable serum HBV-DNA can provide a similar risk of postoperative HCC recurrence.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Oncology
Yujun Park, Soo Kyung Nam, Soo Hyun Seo, Kyoung Un Park, Hyeon Jeong Oh, Young Suk Park, Yun-Suhk Suh, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim, Hye Seung Lee
Summary: In this study, PCR-based MSI testing and IHC for MMR protein expression were comprehensively analyzed and compared in gastric cancer patients. Among the 5,676 cases, the majority were microsatellite stable/MSI-low, while a small percentage showed MSI-high and loss of MLH1 expression. Re-evaluation of discordant/indeterminate cases revealed the need for complementary testing in order to improve accuracy.
JOURNAL OF GASTRIC CANCER
(2023)
Correction
Oncology
Yonghoon Choi, Nayoung Kim, Chang Yong Yun, Yoon Jin Choi, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Sang-Hoon Ahn, Do Joong Park, Hye Seung Lee, Ji-Won Kim, Jin Won Kim, Keun-Wook Lee, Won Chang, Ji Hoon Park, Yoon Jin Lee, Kyoung Ho Lee, Young Hoon Kim, Dong Ho Lee, Hyung-Ho Kim
Article
Gastroenterology & Hepatology
Du Hyun Song, Nayoung Kim, Hyeong Ho Jo, Sangbin Kim, Yonghoon Choi, Hyeon Jeong Oh, Hye Seung Lee, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Dong Ho Lee, So Hyun Kang, Young Suk Park, Sang-Hoon Ahn, Yun-Suhk Suh, Do Joong Park, Hyung Ho Kim, Ji-Won Kim, Keun-Wook Lee, Won Chang, Ji Hoon Park, Jin Won Kim, Yoon Jin Lee, Kyoung Ho Lee, Young Hoon Kim, Soyeon Ahn, Young-Joon Surh
Summary: This study aimed to identify risk factors for synchronous multiple gastric cancer (SMGC). Data from 14,603 patients with gastric cancer were analyzed, and the incidence of SMGC was found to be 4.04%, which was associated with male sex, age ≥65 years, and early gastric cancer. Unlike single gastric cancer, SMGC had a high survival rate.
Article
Gastroenterology & Hepatology
Hye Kyung Hyun, Hye Won Lee, Jihye Park, Soo Jung Park, Jae Jun Park, Tae Il Kim, Jae Seung Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Seung Up Kim, Jae Hee Cheon
Summary: This study investigated the effects of nonalcoholic fatty liver disease (NAFLD) on the outcome of inflammatory bowel disease (IBD) patients. The results showed that the presence of NAFLD may increase the risk of clinical relapse in patients with IBD. Additionally, the study found that hepatic steatosis was significantly associated with increased risks of clinical relapse in patients with ulcerative colitis and Crohn's disease, while fibrotic burden in the liver was not.
Article
Gastroenterology & Hepatology
Hye Yeon Chon, Han Ah Lee, Soo Young Park, Yeon Seok Seo, Sang Gyune Kim, Chang Hun Lee, Tae Hee Lee, Sang Hoon Ahn, Vincent Wai-Sun Wong, Terry Cheuk-Fung Yip, Lilian Yan Liang, In Hee Kim, Grace Lai-Hung Wong, Seung Up Kim
Summary: This study compared the predictive accuracy of three risk prediction models for hepatocellular carcinoma (HCC) development after 5 years of antiviral therapy in patients with chronic hepatitis B. The results showed that the SAGE-B and CAGE-B models might be better than the PAGE-B model in predicting HCC development after 5 years of treatment.
JOURNAL OF DIGESTIVE DISEASES
(2023)
Article
Gastroenterology & Hepatology
David Sooik Kim, Beom Kyung Kim, Jae Seung Lee, Hye Won Lee, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Nikolaos Pyrsopoulos, Seung Up Kim
Summary: This study validated the predictive performance of the CHESS-ALARM model in patients with HBV-related liver cirrhosis and compared it with other TE-based models. The results showed that CHESS-ALARM had similar predictive performance as LSPS, PH, varices risk scores, ALBI, and ALBI-FIB-4.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Eugene Han, Ho Soo Chun, Yong-ho Lee, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Sang Hoon Ahn, Seung Up Kim
Summary: The risks of sarcopenia and cardiovascular disease (CVD) are significantly higher in metabolic dysfunction-associated fatty liver disease (MAFLD) group compared to non-metabolic risk (MR) non-alcoholic fatty liver disease (NAFLD) group. However, the risk does not differ according to fibrotic burden in non-MR NAFLD group. The MAFLD criteria might be better for identifying high-risk fatty liver disease than the NAFLD criteria.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Surgery
Chami Im, Young Suk Park, Sa-Hong Min, So Hyun Kang, Sangjun Lee, Eunju Lee, Mira Yoo, Duyeong Hwang, Sang-Hoon Ahn, Yun Suhk Suh, Do Joong Park, Hyung-Ho Kim
Summary: This study investigated the association between antiplatelet and/or anticoagulant therapies and the risk of postoperative major bleeding in laparoscopic gastric cancer surgery. The study found that preoperative use of antiplatelets and/or anticoagulants did not significantly increase the risk of postoperative major bleeding.
ANNALS OF SURGICAL TREATMENT AND RESEARCH
(2023)
Article
Surgery
Sin Hye Park, Woo Jin Hyung, Han-Kwang Yang, Young-Kyu Park, Hyuk-Joon Lee, Ji Yeong An, Wook Kim, Hyoung-Il Kim, Hyung-Ho Kim, Seung Wan Ryu, Hoon Hur, Min-Chan Kim, Seong-Ho Kong, Gyu Seok Cho, Jin-Jo Kim, Do Joong Park, Young-Woo Kim, Jong Won Kim, Joo-Ho Lee, Sang-Uk Han, Keun Won Ryu
Summary: The study did not find any survival benefit from regular follow-up after radical gastrectomy for gastric cancer, and it suggests the need for a prospective randomized controlled trial to determine the survival benefit.
BRITISH JOURNAL OF SURGERY
(2023)