Article
Dermatology
Xiaoyun Liu, Xia Wu, Wenjun Fan
Summary: This study evaluated the effectiveness and safety of endoscopic submucosa dissection (ESD) compared with endoscopic mucosal resection (EMR) in treating early-stage stomach cancer. The meta-analysis results showed that there was no significant difference between EMR and ESD in terms of postoperative hemorrhage, but EMR had a lower rate of postoperative perforation.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Gastroenterology & Hepatology
Hiroyuki Ono, Kenshi Yao, Mitsuhiro Fujishiro, Ichiro Oda, Noriya Uedo, Satoshi Nimura, Naohisa Yahagi, Hiroyasu Iishi, Masashi Oka, Yoichi Ajioka, Kazuma Fujimoto
Summary: In response to the rapid development in endoscopic treatments for early gastric cancer, the Japan Gastroenterological Endoscopy Society collaborated with the Japanese Gastric Cancer Association to produce guidelines in 2014. The revised second edition covers seven categories to provide a comprehensive overview of knowledge in the field.
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Yoshito Hayashi, Waku Hatta, Yosuke Tsuji, Toshiyuki Yoshio, Yohei Yabuuchi, Shu Hoteya, Shigetsugu Tsuji, Yasuaki Nagami, Takuto Hikichi, Masakuni Kobayashi, Yoshinori Morita, Tetsuya Sumiyoshi, Mikitaka Iguchi, Hideomi Tomida, Takuya Inoue, Tatsuya Mikami, Kenkei Hasatani, Jun Nishikawa, Tomoaki Matsumura, Hiroko Nebiki, Dai Nakamatsu, Ken Ohnita, Haruhisa Suzuki, Hiroya Ueyama, Mitsushige Sugimoto, Shinjiro Yamaguchi, Tomoki Michida, Tomoyuki Yada, Yoshiro Asahina, Toshiaki Narasaka, Shiko Kuribayashi, Shu Kiyotoki, Katsuhiro Mabe, Akimitsu Miyake, Mitsuhiro Fujishiro, Atsushi Masamune, Tetsuo Takehara
Summary: Nonsevere gastric mucosal atrophy was identified as a risk factor for post-ESD bleeding in H. pylori-negative patients, but not in H. pylori-positive patients. In H. pylori-negative patients, the rate of post-ESD bleeding increased in a stepwise manner for patients continuing antithrombotic drug use, patients who withdrew antithrombotic drug use, and antithrombotic drug nonusers.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Surgery
Chang Kyo Oh, Bo-In Lee, Sung Hak Lee, Seung-Jun Kim, Han Hee Lee, Chul-Hyun Lim, Jin Su Kim, Yu Kyung Cho, Jae Myung Park, Young-Seok Cho, In Seok Lee, Myung-Gyu Choi
Summary: The study found that the use of CSI-EMR does not increase the complete or en bloc resection rate of colorectal lesions with SSL endoscopic features, but does increase the R0 resection rate. Although the procedure time is longer for CSI-EMR, there is no significant difference in adverse events or recurrence rate compared to EMR. Further evaluation is needed to assess the association of CSI-EMR with R0 resection and non-recurrence.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Gastroenterology & Hepatology
Zhao Wu Meng, Kirles Bishay, Marcus Vaska, Yibing Ruan, Mohammad A. Al-Haddad, Sherif E. Elhanafi, Bashar J. Qumseya, Paul J. Belletrutti, Richdeep Gill, Estifanos Debru, Steven J. Heitman, Darren R. Brenner, Nauzer Forbes
Summary: For metachronous EGC, ESD or surgery is preferred over EMR depending on local expertise and patient preferences, largely due to a higher risk of incomplete resection with EMR.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Surgery
Richard F. Knoop, Ahmad Amanzada, Golo Petzold, Volker Ellenrieder, Michael Engelhardt, Albrecht Neesse, Sebastian C. B. Bremer, Steffen Kunsch
Summary: With an external additional working channel (AWC), endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) can be extended to EMR+ and ESD+ techniques. These novel techniques were systematically compared to EMR and ESD under the use of a double-channel endoscope (DC). The results showed that AWC can easily transform a standard endoscope to double-channel functionality, and EMR+ and ESD+ are non-inferior to EMR and ESD when using a double-channel endoscope.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Oncology
Alexandre Moraes Bestetti, Diogo Turiani Hourneaux de Moura, Igor Mendonca Proenca, Epifanio Silvino do Monte Junior, Igor Braga Ribeiro, Joao Guilherme Ribeiro Jordao Sasso, Angelo So Taa Kum, Sergio A. Sanchez-Luna, Wanderley Marques Bernardo, Eduardo Guimaraes Hourneaux de Moura
Summary: Endoscopic resection (ER) and surgery are both safe and effective treatments for early gastric cancer patients, with ER associated with lower rates of adverse events and shorter hospital stay. However, ER has lower complete resection rates and higher recurrence rates compared to surgery, although overall survival and cancer-specific survival are similar between the two approaches.
FRONTIERS IN ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Saowanee Ngamruengphong, Lorenzo Ferri, Hiroyuki Aihara, Peter V. Draganov, Dennis J. Yang, Yaseen B. Perbtani, Terry L. Jue, Craig A. Munroe, Eshandeep S. Boparai, Neal A. Mehta, Amit Bhatt, Nikhil A. Kumta, Mohamed O. Othman, Michael Mercado, Huma Javaid, Abdul Aziz Aadam, Amanda Siegel, Theodore W. James, Ian S. Grimm, John M. DeWitt, Aleksey Novikov, Alexander Schlachterman, Thomas Kowalski, Jason Samarasena, Rintaro Hashimoto, Nabil El Hage Chehade, John Lee, Kenneth Chang, Bailey Su, Michael B. Ujiki, Amit Mehta, Reem Z. Sharaiha, David L. Carr-Locke, Alex Chen, Michael Chen, Yen-I. Chen, MirMilad Pourmousavi Khoshknab, Rui Wang, Tossapol Kerdsirichairat, Yutaka Tomizawa, Daniel von Renteln, Vivek Kumbhari, Mouen A. Khashab, Robert Bechara, Michael Karasik, Neej J. Patel, Norio Fukami, Makoto Nishimura, Yuri Hanada, Louis M. Wong Kee Song, Monika Laszkowska, Andrew Y. Wang, Joo Ha Hwang, Shai Friedland, Amrita Sethi, Antony N. Kalloo
Summary: Endoscopic submucosal dissection (ESD) is a highly effective treatment for superficial gastric neoplasia in North America, with low risk of local recurrence. Close endoscopic surveillance post-ESD is crucial for identifying and treating metachronous lesions.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Medicine, General & Internal
Yinuo Zhao, Huogen Wang, Yanyan Fan, Chaohui Jin, Qinwei Xu, Jiyong Jing, Tianqiao Zhang, Xuedong Zhang, Wanyuan Chen
Summary: In this study, we developed a software pipeline named "Pathology Helper" to assist in the construction of high-quality mucosal recovery maps, reducing the workload of endoscopists and pathologists, while accelerating their ability to diagnose EGC.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Xiaoqian Ma, Qian Zhang, Shengtao Zhu, Shutian Zhang, Xiujing Sun
Summary: This study aimed to identify factors leading to non-curative resection for EGC and develop a predictive model. Patient were grouped into curative and non-curative resection groups, with older age, large tumor size, submucosal lesion identified as risk factors for non-curative resection. The risk nomogram showed good discrimination performance in predicting non-curative resection.
FRONTIERS IN MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Paul Doumbe-Mandengue, Anna Pellat, Arthur Belle, Einas Abou Ali, Rachel Hallit, Frederic Beuvon, Benoit Terris, Stanislas Chaussade, Romain Coriat, Maximilien Barret
Summary: This study compared the efficacy of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) in the treatment of early esophageal adenocarcinoma. The results showed that ESD was superior to EMR in terms of surgical characteristics and treatment outcomes. ESD should be more widely adopted for the resection of esophageal lesions suspected of harboring early esophageal adenocarcinoma.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
(2023)
Article
Gastroenterology & Hepatology
Kenichiro Okimoto, Tomoaki Matsumura, Keisuke Matsusaka, Yosuke Inaba, Tsubasa Ishikawa, Naoki Akizue, Tatsuya Kaneko, Masayuki Ota, Yuki Ohta, Takashi Taida, Keiko Saito, Sadahisa Ogasawara, Daisuke Maruoka, Jun Kato, Jun-ichiro Ikeda, Naoya Kato
Summary: This randomized controlled trial aimed to evaluate the short-term outcomes of underwater endoscopic mucosal resection (UEMR) and endoscopic submucosal dissection (ESD) for 21-30 mm colonic polyps. The results showed that ESD had a significantly higher R0 resection rate compared to UEMR, while the en bloc resection rate was similar between the two techniques. The UEMR group had a significantly shorter treatment time than the ESD group.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Gastroenterology & Hepatology
Hiroyuki Aihara, Vladimir Kushnir, Gobind S. Anand, Lisa Cassani, Prabhleen Chahal, Sunil Dacha, Anna Duloy, Sahar Ghassemi, Christopher Huang, Thomas E. Kowalski, Emad Qayed, Sunil G. Sheth, C. Roberto Simons-Linares, Jason R. Taylor, Sarah B. Umar, Stacie A. F. Vela, Catharine M. Walsh, Renee L. Williams, Mihir S. Wagh
Summary: This document is part of a series prepared by the American Society for Gastrointestinal Endoscopy Training Committee, offering recommendations for a training curriculum focusing on endoscopic mucosal resection (EMR). It serves as an overview of favored techniques and a guide to resources for training directors, endoscopists, and trainees.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Oncology
Yong Liu, Shun He, Yueming Zhang, Lizhou Dou, Xiao Liu, Xinying Yu, Ning Lu, Liyan Xue, Guiqi Wang
Summary: ESD is an acceptable first-line endoscopic treatment for type II EGJ neoplasm, but it is time-consuming and has a higher rate of adverse events. EMR is a safe and alternative technique, particularly when en bloc resection can be achieved.
ANNALS OF TRANSLATIONAL MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Lady Katherine Mejia Perez, Dennis Yang, Peter Draganov, Salmaan Jawaid, Amitabh Chak, John Dumot, Omar Alaber, John J. Vargo, Sunguk Jang, Neal Mehta, Norio Fukami, Tiffany Chua, Moamen Gabr, Praneeth Kudaravalli, Hiroyuki Aihara, Fauze Maluf-Filho, Saowanee Ngamruengphong, Milad Pourmousavi Khoshknab, Amit Bhatt
Summary: The study compared the outcomes of endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) for early Barrett's esophagus neoplasia, finding that ESD had higher en bloc and R0 resection rates, lower recurrence/residual disease rates, and less need for repeat endoscopic treatments compared to EMR.