Respiratory syncytial virus protein structure, function and implications for subunit vaccine development

Respiratory Syncytial Virus and Other Respiratory Viral Infections in Older Adults With Moderate to Severe Influenza-like Illness

(2014) Ann R. Falsey et al.   JOURNAL OF INFECTIOUS DISEASES

Proof of principle for epitope-focused vaccine design

(2014) Bruno E. Correia et al.   NATURE

Cell-mediated immune responses to respiratory syncytial virus infection

(2014) Bessey Geevarghese et al.   Human Vaccines & Immunotherapeutics

A Novel Investigational Fc-Modified Humanized Monoclonal Antibody, Motavizumab-YTE, Has an Extended Half-Life in Healthy Adults

(2013) Gabriel J. Robbie et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An update on safety and immunogenicity of vaccines containing emulsion-based adjuvants

(2013) Christopher B Fox et al.   Expert Review of Vaccines

Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region

(2013) Salim Abdulla et al.   MALARIA JOURNAL

Key roles of adjuvants in modern vaccines

(2013) Steven G Reed et al.   NATURE MEDICINE

Nanoparticle Vaccines Encompassing the Respiratory Syncytial Virus (RSV) G Protein CX3C Chemokine Motif Induce Robust Immunity Protecting from Challenge and Disease

(2013) Patricia A. Jorquera et al.   PLoS One

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

(2013) J. S. McLellan et al.   SCIENCE

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

(2013) J. S. McLellan et al.   SCIENCE

Strategic priorities for respiratory syncytial virus (RSV) vaccine development

(2013) L.J. Anderson et al.   VACCINE

Adults 65 Years Old and Older Have Reduced Numbers of Functional Memory T Cells to Respiratory Syncytial Virus Fusion Protein

(2012) Anu Cherukuri et al.   Clinical and Vaccine Immunology

Role of Neutralizing Antibodies in Adults With Community-Acquired Pneumonia by Respiratory Syncytial Virus

(2012) V. Luchsinger et al.   CLINICAL INFECTIOUS DISEASES

Hospitalizations Associated With Influenza and Respiratory Syncytial Virus in the United States, 1993–2008

(2012) Hong Zhou et al.   CLINICAL INFECTIOUS DISEASES

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention

(2012) M. Magro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety and immunogenicity of a Sf9 insect cell-derived respiratory syncytial virus fusion protein nanoparticle vaccine

(2012) Gregory M. Glenn et al.   VACCINE

An adjuvanted respiratory syncytial virus fusion protein induces protection in aged BALB/c mice

(2012) Anu Cherukuri et al.   Immunity & Ageing

Comparative immunogenicity and safety of human papillomavirus (HPV)-16/18 vaccine and HPV-6/11/16/18 vaccine

(2011) Mark H. Einstein et al.   Human vaccines & immunotherapeutics

Analysis of Respiratory Syncytial Virus Preclinical and Clinical Variants Resistant to Neutralization by Monoclonal Antibodies Palivizumab and/or Motavizumab

(2011) Qing Zhu et al.   JOURNAL OF INFECTIOUS DISEASES

Design and Characterization of Epitope-Scaffold Immunogens That Present the Motavizumab Epitope from Respiratory Syncytial Virus

(2011) Jason S. McLellan et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

(2011) J. S. McLellan et al.   JOURNAL OF VIROLOGY

Soluble Respiratory Syncytial Virus Fusion Protein in the Fully Cleaved, Pretriggered State Is Triggered by Exposure to Low-Molarity Buffer

(2011) S. Chaiwatpongsakorn et al.   JOURNAL OF VIROLOGY

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

(2011) K. A. Swanson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In-depth process understanding of RECOMBIVAX HB® maturation and potential epitope improvements with redox treatment: Multifaceted biochemical and immunochemical characterization

(2011) Qinjian Zhao et al.   VACCINE

Progress in understanding and controlling respiratory syncytial virus: Still crazy after all these years

(2011) Peter L. Collins et al.   VIRUS RESEARCH

New adjuvants for human vaccines

(2010) M Lamine Mbow et al.   CURRENT OPINION IN IMMUNOLOGY

Tetanus toxoid immunization to reduce mortality from neonatal tetanus

(2010) H. Blencowe et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

Age related changes in T cell mediated immune response and effector memory to Respiratory Syncytial Virus (RSV) in healthy subjects

(2010) Maria Grazia Cusi et al.   Immunity & Ageing

Humoral immunity to respiratory syncytial virus in young and elderly adults

(2009) C. TERROSI et al.   EPIDEMIOLOGY AND INFECTION

Vaccination To Induce Antibodies Blocking the CX3C-CX3CR1 Interaction of Respiratory Syncytial Virus G Protein Reduces Pulmonary Inflammation and Virus Replication in Mice

(2009) W. Zhang et al.   JOURNAL OF VIROLOGY

Generation of stable monoclonal antibody–producing B cell receptor–positive human memory B cells by genetic programming

(2009) Mark J Kwakkenbos et al.   NATURE MEDICINE

The Burden of Respiratory Syncytial Virus Infection in Young Children

(2009) Caroline Breese Hall et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Role of Neutralizing Antibodies in Protection of American Indian Infants Against Respiratory Syncytial Virus Disease

(2009) Angelia Eick et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Motavizumab for Prophylaxis of Respiratory Syncytial Virus in High-Risk Children: A Noninferiority Trial

(2009) X. Carbonell-Estrany et al.   PEDIATRICS

Relative Impact of Influenza and Respiratory Syncytial Virus in Young Children

(2009) F. T. Bourgeois et al.   PEDIATRICS

Respiratory syncytial virus neutralizing antibodies in cord blood, respiratory syncytial virus hospitalization, and recurrent wheeze

(2008) Lone Graff Stensballe et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Comparison of the Safety and Immunogenicity of 2 Respiratory Syncytial Virus (RSV) Vaccines— Nonadjuvanted Vaccine or Vaccine Adjuvanted with Alum—Given Concomitantly with Influenza Vaccine to High‐Risk Elderly Individuals

(2008) Ann R. Falsey et al.   JOURNAL OF INFECTIOUS DISEASES

The Secreted Form of Respiratory Syncytial Virus G Glycoprotein Helps the Virus Evade Antibody-Mediated Restriction of Replication by Acting as an Antigen Decoy and through Effects on Fc Receptor-Bearing Leukocytes

(2008) A. Bukreyev et al.   JOURNAL OF VIROLOGY

Effectiveness of Maternal Influenza Immunization in Mothers and Infants

(2008) K. Zaman et al.   NEW ENGLAND JOURNAL OF MEDICINE