Regulatory T cells and Th17 cells in viral infections: implications for multiple sclerosis and myocarditis

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

Intratumoral Expression of IL-17 and Its Prognostic Role in Gastric Adenocarcinoma Patients

(2012) Ju-gao Chen et al.   International Journal of Biological Sciences

CD24 Gene Allele Variation Is Not Associated with Oligoclonal IgG Bands and IgG Index of Multiple Sclerosis Patients

(2012) Mohammad Saadatnia et al.   NEUROIMMUNOMODULATION

A Randomized Case–Control Study of Dynamic Changes in Peripheral Blood Th17/Treg Cell Balance and Interleukin-17 Levels in Highly Active Antiretroviral-Treated HIV Type 1/AIDS Patients

(2011) Yan He et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Cytomegalovirus-Specific Regulatory and Effector T Cells Share TCR Clonality-Possible Relation to Repetitive CMV Infections

(2011) S. Schwele et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Japanese macaque encephalomyelitis: A spontaneous multiple sclerosis-like disease in a nonhuman primate

(2011) Michael K. Axthelm et al.   ANNALS OF NEUROLOGY

Galectin-9 administration ameliorates CVB3 induced myocarditis by promoting the proliferation of regulatory T cells and alternatively activated Th2 cells

(2011) Kun Lv et al.   CLINICAL IMMUNOLOGY

CD4+CD25+Foxp3+ Regulatory T Cells Promote Th17 Cells In Vitro and Enhance Host Resistance in Mouse Candida albicans Th17 Cell Infection Model

(2011) Pushpa Pandiyan et al.   IMMUNITY

Low Level of Regulatory T Cells and Maintenance of Balance Between Regulatory T Cells and TH17 Cells in HIV-1–Infected Elite Controllers

(2011) Lea Brandt et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Virus expanded regulatory T cells control disease severity in the Theiler’s virus mouse model of MS

(2011) Maureen H. Richards et al.   JOURNAL OF AUTOIMMUNITY

Th17 cells are increased with severity of liver inflammation in patients with chronic hepatitis C

(2011) Qing Chang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

NK Cell Adoptive Transfer Combined with Ontak-Mediated Regulatory T Cell Elimination Induces Effective Adaptive Antitumor Immune Responses

(2011) M. Salagianni et al.   JOURNAL OF IMMUNOLOGY

IL-17 + Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer

(2011) Ilona Kryczek et al.   JOURNAL OF IMMUNOLOGY

IL-17 Boosts Proinflammatory Outcome of Antiviral Response in Human Cells

(2011) Grigory Ryzhakov et al.   JOURNAL OF IMMUNOLOGY

Control of Pathogenic CD4 T Cells and Lethal Immunopathology by Signaling Immunoadaptor DAP12 during Influenza Infection

(2011) Sarah McCormick et al.   JOURNAL OF IMMUNOLOGY

CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game

(2011) S. A. Long et al.   JOURNAL OF IMMUNOLOGY

Role of IL-17 and Th17 Cells in Herpes Simplex Virus-Induced Corneal Immunopathology

(2011) A. Suryawanshi et al.   JOURNAL OF IMMUNOLOGY

Th17 expansion in MS patients is counterbalanced by an expanded CD39+ regulatory T cell population during remission but not during relapse

(2011) Evelyn Peelen et al.   JOURNAL OF NEUROIMMUNOLOGY

Protective HIV-specific CD8+ T cells evade Treg cell suppression

(2011) Shokrollah Elahi et al.   NATURE MEDICINE

Direct Gene Transfer with IP-10 Mutant Ameliorates Mouse CVB3-Induced Myocarditis by Blunting Th1 Immune Responses

(2011) Yan Yue et al.   PLoS One

Destruction of Lymphoid Organ Architecture and Hepatitis Caused by CD4+ T Cells

(2011) Matthias S. Matter et al.   PLoS One

Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points

(2011) K. K. Dietze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

Evidence for Viral Etiology of Multiple Sclerosis

(2011) Alexandros Tselis   SEMINARS IN NEUROLOGY

The role of Th17 cells and regulatory T cells in Coxsackievirus B3-induced myocarditis

(2011) Yuquan Xie et al.   VIROLOGY

Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of coxsackievirus b3-induced viral myocarditis reduces myocardium inflammation

(2011) Yang Fan et al.   Virology Journal

Gut Microbiota, Immunity, and Disease: A Complex Relationship

(2011) Michele M. Kosiewicz et al.   Frontiers in Microbiology

CD4+CD25+ T Regulatory Cells Inhibit CD8+ IFN-γ Production During Acute and Chronic FIV Infection Utilizing a Membrane TGF-β-Dependent Mechanism

(2010) Jonathan E. Fogle et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Regulatory T Cells Protect Mice Against Coxsackievirus-Induced Myocarditis Through the Transforming Growth Factor β–Coxsackie-Adenovirus Receptor Pathway

(2010) Yu Shi et al.   CIRCULATION

Genetic control of the inflammatory T-cell response in regulatory T-cell deficient scurfy mice

(2010) Rahul Sharma et al.   CLINICAL IMMUNOLOGY

Th17 Cells Contribute to Viral Replication in Coxsackievirus B3-Induced Acute Viral Myocarditis

(2010) J. Yuan et al.   JOURNAL OF IMMUNOLOGY

Foxp3+ CD4 Regulatory T Cells Limit Pulmonary Immunopathology by Modulating the CD8 T Cell Response during Respiratory Syncytial Virus Infection

(2010) R. B. Fulton et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Inhibit T Cell Proliferation and Decrease Demyelination in Mice Chronically Infected with a Coronavirus

(2010) K. Trandem et al.   JOURNAL OF IMMUNOLOGY

Generation and Differentiation of IL-17-Producing CD4+ T Cells in Malignant Pleural Effusion

(2010) Z.-J. Ye et al.   JOURNAL OF IMMUNOLOGY

Susceptibility of Human Th17 Cells to Human Immunodeficiency Virus and Their Perturbation during Infection

(2010) Aimee El Hed et al.   JOURNAL OF INFECTIOUS DISEASES

Interferon-gamma negatively regulates Th17-mediated immunopathology during mouse hepatitis virus infection

(2010) Wei Yang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Preferential Induction of Protective T Cell Responses to Theiler's Virus in Resistant (C57BL/6 x SJL)F1 Mice

(2010) Y.-H. Jin et al.   JOURNAL OF VIROLOGY

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

(2010) Kamran Ghoreschi et al.   NATURE

Human ROR t+ TH17 cells preferentially differentiate from naive FOXP3+Treg in the presence of lineage-specific polarizing factors

(2010) D. Valmori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4+CD25+ T regulatory cells from FIV+ cats induce a unique anergic profile in CD8+ lymphocyte targets

(2010) Jonathan E Fogle et al.   Retrovirology

Disturbed regulatory T cell homeostasis in multiple sclerosis

(2010) Koen Venken et al.   TRENDS IN MOLECULAR MEDICINE

Th17 and regulatory T cells: implications for AIDS pathogenesis

(2010) Bittoo Kanwar et al.   Current Opinion in HIV and AIDS

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments

(2009) I. Kryczek et al.   BLOOD

The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response

(2009) G. Zelinskyy et al.   BLOOD

Treatment and Prevention of Experimental Autoimmune Myocarditis with CD28 Superagonists

(2009) Shu Wang et al.   CARDIOLOGY

Viral Myocarditis

(2009) Toshitaka Yajima et al.   CIRCULATION

RORC2: The master of human Th17 cell programming

(2009) Derya Unutmaz   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutralization of IL-17 inhibits the production of anti-ANT autoantibodies in CVB3-induced acute viral myocarditis

(2009) Jing Yuan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Hepatitis C Virus Non-structural NS5A Protein Impairs Both the Innate and Adaptive Hepatic Immune Responsein Vivo

(2009) Malte Kriegs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Th17 Cells Facilitate the Humoral Immune Response in Patients with Acute Viral Myocarditis

(2009) Jing Yuan et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection

(2009) Wanqiu Hou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-Specific Abundance of Regulatory T Cells Correlates with CD8+ T Cell Dysfunction and Chronic Retrovirus Loads

(2009) L. Myers et al.   JOURNAL OF IMMUNOLOGY

Critical Role of IL-17RA in Immunopathology of Influenza Infection

(2009) C. R. Crowe et al.   JOURNAL OF IMMUNOLOGY

Tc17, a Unique Subset of CD8 T Cells That Can Protect against Lethal Influenza Challenge

(2009) H. Hamada et al.   JOURNAL OF IMMUNOLOGY

Glatiramer acetate improves regulatory T-cell function by expansion of naive CD4+CD25+FOXP3+CD31+ T-cells in patients with multiple sclerosis

(2009) Juergen Haas et al.   JOURNAL OF NEUROIMMUNOLOGY

Epstein–Barr virus and multiple sclerosis

(2009) Daniela Pohl   JOURNAL OF THE NEUROLOGICAL SCIENCES

The history of multiple sclerosis: the changing frame of the disease over the centuries

(2009) T. Jock Murray   JOURNAL OF THE NEUROLOGICAL SCIENCES

Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus

(2009) Agnès Doreau et al.   NATURE IMMUNOLOGY

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE

Myocarditis

(2009) Leslie T. Cooper   NEW ENGLAND JOURNAL OF MEDICINE

HLA class I allele and haplotype diversity in Ugandans supports the presence of a major east African genetic cluster

(2009) G. H. Kijak et al.   TISSUE ANTIGENS

Role of regulatory T cells in coronavirus-induced acute encephalitis

(2009) Daniela Anghelina et al.   VIROLOGY

Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection

(2009) David Favre et al.   PLoS Pathogens

Regulatory T Cells Suppress Antiviral Immune Responses and Increase Viral Loads during Acute Infection with a Lymphotropic Retrovirus

(2009) Gennadiy Zelinskyy et al.   PLoS Pathogens

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

(2008) J. M. Brenchley et al.   BLOOD

Alteration of IL-17 Related Protein Expressions in Experimental Autoimmune Myocarditis and Inhibition of IL-17 by IL-10-Ig Fusion Gene Transfer

(2008) He Chang et al.   CIRCULATION JOURNAL

Phenotypic Analysis of Prostate-Infiltrating Lymphocytes Reveals TH17 and Treg Skewing

(2008) K. S. Sfanos et al.   CLINICAL CANCER RESEARCH

Acute viral myocarditis

(2008) R. Dennert et al.   EUROPEAN HEART JOURNAL

Foxp3 Inhibits RORγt-mediatedIL-17AmRNA Transcription through Direct Interaction with RORγt

(2008) Kenji Ichiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Downregulation of IL-17 and IL-6 in the central nervous system by glatiramer acetate in experimental autoimmune encephalomyelitis

(2008) S BEGUMHAQUE et al.   JOURNAL OF NEUROIMMUNOLOGY

Virus-Specific Interleukin-17-Producing CD4+ T Cells Are Detectable in Early Human Immunodeficiency Virus Type 1 Infection

(2008) F. Y. Yue et al.   JOURNAL OF VIROLOGY

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

(2008) Liang Zhou et al.   NATURE

IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

(2008) Elisabetta Volpe et al.   NATURE IMMUNOLOGY

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY

Anomalous Type 17 Response to Viral Infection by CD8+ T Cells Lacking T-bet and Eomesodermin

(2008) A. M. Intlekofer et al.   SCIENCE

Coordination of Early Protective Immunity to Viral Infection by Regulatory T Cells

(2008) J. M. Lund et al.   SCIENCE